Kirkland, James L.

Epigenetic and senescence markers indicate an accelerated ageing-like state in women with preeclamptic pregnancies

Suvakov, S., Ghamrawi, R., Cubro, H., Tu, H., White, W. M., Tobah, Y. S. B., Milic, N. M., Grande, J. P., Cunningham, J. M., Chebib, F. T., et al. (2021) · EBioMedicine

Pregnancy and preeclampsia studiesTelomeres, Telomerase, and Senescence

Cited by 38

Markers of cellular senescence are elevated in murine blastocysts cultured in vitro: molecular consequences of culture in atmospheric oxygen

Meuter, A., Rogmann, L.-M., Winterhoff, B. J., Tchkonia, T., Kirkland, J. L., & Morbeck, D. E. (2014) · Journal of Assisted Reproduction and Genetics

Reproductive Biology and FertilityTelomeres, Telomerase, and Senescence

Cited by 36

In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers

Samakkarnthai, P., Saul, D., Zhang, L., Aversa, Z., Doolittle, M. L., Sfeir, J. G., Kaur, J., Atkinson, E. J., Edwards, J. R., Russell, G. G., et al. (2023) · Aging

Telomeres, Telomerase, and SenescenceBone health and treatments

Cited by 34

Barriers to the Preclinical Development of Therapeutics that Target Aging Mechanisms: Table 1.

Burd, C. E., Gill, M. S., Niedernhofer, L. J., Robbins, P. D., Austad, S. N., Barzilai, N., & Kirkland, J. L. (2016) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 28

Evaluation of exploratory fluid biomarkers from a phase 1 senolytic trial in mild Alzheimer's disease

Garbarino, V. R., Palavicini, J. P., Melendez, J., Barthelemy, N. R., He, Y., Kautz, T. F., Lopez-Cruzan, M., Mathews, J. J., Xu, P., Zhang, B., et al. (2025) · Neurotherapeutics

Alzheimer's disease research and treatmentsTelomeres, Telomerase, and Senescence

Cited by 26

Obesity, Senescence, and Senolytics

Chaib, S., Tchkonia, T., & Kirkland, J. L. (2021) · Handbook of Experimental Pharmacology

Telomeres, Telomerase, and SenescenceSirtuins and Resveratrol in Medicine

Cited by 22

p21-senescent cells drive pancreatic islet dysfunction through targetable paracrine signaling in type 2 diabetes

Iwasaki, K., Carapeto, P., Abarca, C., Hela, F., Sanjines, S., Pena, S., Le, S., Pan, H., Jackson, M., Cahill, C., et al. (2026) · JCI Insight

Pancreatic function and diabetesTelomeres, Telomerase, and Senescence

Cited by 4