Howard, Rebecca J.

Seeking structural specificity: direct modulation of pentameric ligand-gated ion channels by alcohols and general anesthetics

Howard, R. J., Trudell, J. R., & Harris, R. A. (2014) · Pharmacological Reviews

Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology Research

Cited by 56

Structure and dynamics of differential ligand binding in the human ρ-type GABAA receptor

Cowgill, J., Fan, C., Haloi, N., Tobiasson, V., Zhuang, Y., Howard, R. J., & Lindahl, E. (2023) · Neuron

Neuroscience and Neuropharmacology ResearchReceptor Mechanisms and Signaling

Cited by 25

Allosteric potentiation of a ligand-gated ion channel is mediated by access to a deep membrane-facing cavity

Heusser, S. A., Lycksell, M., Wang, X., McComas, S. E., Howard, R. J., & Lindahl, E. (2018) · Proceedings of the National Academy of Sciences

Nicotinic Acetylcholine Receptors StudyAnesthesia and Sedative Agents

Cited by 23

Resolving the conformational ensemble of a membrane protein by integrating small-angle scattering with AlphaFold

Lidbrink, S. E., Howard, R. J., Haloi, N., & Lindahl, E. (2025) · PLOS Computational Biology

Protein Structure and DynamicsReceptor Mechanisms and Signaling

Cited by 9

Resolving the conformational ensemble of a membrane protein by integrating small-angle scattering with AlphaFold

Lidbrink, S. E., Howard, R., Haloi, N., & Lindahl, E. (2024) · PLoS Computational Biology

Protein Structure and DynamicsReceptor Mechanisms and Signaling

Cited by 9

Automated simulation-based membrane protein refinement into cryo-EM data

Yvonnesdotter, L., Rovšnik, U., Blau, C., Lycksell, M., Howard, R. J., & Lindahl, E. (2023) · Biophysical Journal

Advanced Electron Microscopy Techniques and ApplicationsProtein Structure and Dynamics

Cited by 6

Engineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization

Abramsson, M. L., Corey, R. A., Škerle, J., Persson, L. J., Andén, O., Oluwole, A. O., Howard, R. J., Lindahl, E., Robinson, C. V., Strisovsky, K., et al. (2024) · eLife

Lipid Membrane Structure and BehaviorProtein Structure and Dynamics

Cited by 4

Engineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization

Abramsson, M. L., Corey, R. A., Skerle, J. L., Persson, L. J., Anden, O., Oluwole, A. O., Howard, R. J., Lindahl, E., Robinson, C. V., Strisovsky, K., et al. (2025) · eLife

Lipid Membrane Structure and BehaviorProtein Structure and Dynamics

Cited by 4

Lipid-facilitated opening of the ADAM10 sheddase revealed by enhanced sampling simulations

Schahl, A., Haloi, N., Carroni, M., Zhang, S., Sattentau, Q. J., Sezgin, E., Delemotte, L., & Howard, R. J. (2025) · Advanced Science

Protease and Inhibitor MechanismsProtein Structure and Dynamics

Cited by 3