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SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

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PGC-1α, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

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The Sir2 Family of Protein Deacetylases

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Substrate and Functional Diversity of Lysine Acetylation Revealed by a Proteomics Survey

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Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins

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Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC‐1α

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Mitochondria and reactive oxygen species

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SIRT4 Inhibits Glutamate Dehydrogenase and Opposes the Effects of Calorie Restriction in Pancreatic β Cells

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SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

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Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice

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Nutrient-Sensitive Mitochondrial NAD+ Levels Dictate Cell Survival

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Mitochondrial Signaling

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Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases

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SIRT5 deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle

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SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress

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Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2

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The mitochondrial energy transduction system and the aging process

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Nuclear activators and coactivators in mammalian mitochondrial biogenesis

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The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide–dependent deacetylase

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Mitochondrial-nuclear communications

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SIRT3, a human SIR2 homologue, is an NAD- dependent deacetylase localized to mitochondria

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Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1α in skeletal muscle

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Regulation of Succinate Dehydrogenase Activity by SIRT3 in Mammalian Mitochondria

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Regulation of Insulin Secretion by SIRT4, a Mitochondrial ADP-ribosyltransferase

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Exogenous NAD Blocks Cardiac Hypertrophic Response via Activation of the SIRT3-LKB1-AMP-activated Kinase Pathway

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Conserved Metabolic Regulatory Functions of Sirtuins

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Structural Basis of Inhibition of the Human NAD+-Dependent Deacetylase SIRT5 by Suramin

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Tissue heterogeneity of the mammalian mitochondrial proteome

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Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes

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SIRT3 reduces lipid accumulation via AMPK activation in human hepatic cells

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Bioenergetics of aging and calorie restriction

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Sirtuins as regulators of metabolism and healthspan

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NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

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SIRT1 and other sirtuins in metabolism

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CD36-mediated ferroptosis dampens intratumoral CD8+ T cell effector function and impairs their antitumor ability

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Mitochondrial and metabolic dysfunction in ageing and age-related diseases

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Untitled work

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Influence of Metabolism on Epigenetics and Disease

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Lysine glutarylation is a protein posttranslational modification regulated by SIRT5

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The sirtuin family in health and disease

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The Role of Sirtuins in Antioxidant and Redox Signaling

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Transcriptional integration of mitochondrial biogenesis

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The world of protein acetylation

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SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1α Destabilization

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Alternative Oxidase: A Mitochondrial Respiratory Pathway to Maintain Metabolic and Signaling Homeostasis during Abiotic and Biotic Stress in Plants

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Isoflavones

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Mitochondria-Ros Crosstalk in the Control of Cell Death and Aging

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Succinate, an intermediate in metabolism, signal transduction, ROS, hypoxia, and tumorigenesis.

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Mitochondrial Dysfunction and Biogenesis in Neurodegenerative diseases: Pathogenesis and Treatment

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A two-way street: reciprocal regulation of metabolism and signalling

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Mitochondrial Dysfunction in Cancer

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Mitochondrial Sirtuin 3: New emerging biological function and therapeutic target

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Sirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activity

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Therapeutic Targeting of the Pyruvate Dehydrogenase Complex/Pyruvate Dehydrogenase Kinase (PDC/PDK) Axis in Cancer

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Are sirtuins viable targets for improving healthspan and lifespan?

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Succinate Dehydrogenase Is a Direct Target of Sirtuin 3 Deacetylase Activity

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Targeting the Warburg effect: A revisited perspective from molecular mechanisms to traditional and innovative therapeutic strategies in cancer

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SIRT4 regulates ATP homeostasis and mediates a retrograde signaling via AMPK

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Mitochondrial Sirtuins and Their Relationships with Metabolic Disease and Cancer

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Pre-diabetes alters testicular PGC1-α/SIRT3 axis modulating mitochondrial bioenergetics and oxidative stress

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SIRT3 is crucial for maintaining skeletal muscle insulin action and protects against severe insulin resistance in high-fat-fed mice

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Adaptive Cellular Stress Pathways as Therapeutic Targets of Dietary Phytochemicals: Focus on the Nervous System

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Neuronal mitochondria-targeted delivery of curcumin by biomimetic engineered nanosystems in Alzheimer's disease mice

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Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells

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G×G×E for Lifespan in Drosophila: Mitochondrial, Nuclear, and Dietary Interactions that Modify Longevity

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Turn up the power - pharmacological activation of mitochondrial biogenesis in mouse models

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Fueling the flame: bioenergy couples metabolism and inflammation

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Hepatic FoxOs Regulate Lipid Metabolism via Modulation of Expression of the Nicotinamide Phosphoribosyltransferase Gene

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SIRT3: Oncogene and Tumor Suppressor in Cancer

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STAT3 Undergoes Acetylation-dependent Mitochondrial Translocation to Regulate Pyruvate Metabolism

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Gene regulation by melatonin linked to epigenetic phenomena

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Sirt3 Protects Cortical Neurons against Oxidative Stress via Regulating Mitochondrial Ca2+ and Mitochondrial Biogenesis

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Programmed death ligand 1 promotes lymph node metastasis and glucose metabolism in cervical cancer by activating integrin β4/SNAI1/SIRT3 signaling pathway

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Compartmentation of NAD+‐dependent signalling

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Molecular basis for hierarchical histone de-β-hydroxybutyrylation by SIRT3

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Mitochondrial sirtuins: Emerging roles in metabolic regulations, energy homeostasis and diseases

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Fine Tuning Our Cellular Factories: Sirtuins in Mitochondrial Biology

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Function and regulation of the mitochondrial Sirtuin isoform Sirt5 in Mammalia

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SIRTUINS AS DRUG TARGETS AFFECTING MITOCHONDRIAL FUNCTIONS

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