Hube, Bernhard

Candida albicans pathogenicity mechanisms

Mayer, F. L., Wilson, D., & Hube, B. (2013) · Virulence

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 1,848

Candida albicans Secreted Aspartyl Proteinases in Virulence and Pathogenesis

Naglik, J. R., Challacombe, S. J., & Hube, B. (2003) · Microbiology and Molecular Biology Reviews

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 1,179

Evolution of pathogenicity and sexual reproduction in eight Candida genomes

Butler, G., Rasmussen, M. D., Lin, M. F., Santos, M. A. S., Sakthikumar, S., Munro, C. A., Rheinbay, E., Grabherr, M., Forche, A., Reedy, J. L., et al. (2009) · Nature

Fungal and yeast genetics researchYeasts and Rust Fungi Studies

Cited by 1,065

Hydrolytic enzymes as virulence factors of Candida albicans

Schaller, M., Borelli, C., Korting, H. C., & Hube, B. (2005) · Mycoses

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 506

Human Anti-fungal Th17 Immunity and Pathology Rely on Cross-Reactivity against Candida albicans

Bacher, P., Hohnstein, T., Beerbaum, E., Röcker, M., Blango, M. G., Kaufmann, S., Röhmel, J., Eschenhagen, P., Grehn, C., Seidel, K., et al. (2019) · Cell

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

Cited by 473

Granulocytes govern the transcriptional response, morphology and proliferation of Candida albicans in human blood

Fradin, C., De Groot, P., MacCallum, D., Schaller, M., Klis, F., Odds, F. C., & Hube, B. (2005) · Molecular Microbiology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 455

Candida albicans dimorphism as a therapeutic target

Jacobsen, I. D., Wilson, D., Wächtler, B., Brunke, S., Naglik, J. R., & Hube, B. (2012) · Expert Review of Anti-infective Therapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 363

Importance of the Candida albicans cell wall during commensalism and infection

Gow, N. A., & Hube, B. (2012) · Current Opinion in Microbiology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 347

The Hyphal-Associated Adhesin and Invasin Als3 of Candida albicans Mediates Iron Acquisition from Host Ferritin

Almeida, R. S., Brunke, S., Albrecht, A., Thewes, S., Laue, M., Edwards, J. E., Filler, S. G., & Hube, B. (2008) · PLoS Pathogens

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 330

The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes

Kasper, L., König, A., Koenig, P.-A., Gresnigt, M. S., Westman, J., Drummond, R. A., Lionakis, M. S., Groß, O., Ruland, J., Naglik, J. R., et al. (2018) · Nature Communications

Inflammasome and immune disordersAntifungal resistance and susceptibility

Cited by 297

In vivo transcript profiling of Candida albicans identifies a gene essential for interepithelial dissemination: C. albicans genes associated with oral candidiasis

Zakikhany, K., Naglik, J. R., Schmidt-Westhausen, A., Holland, G., Schaller, M., & Hube, B. (2007) · Cellular Microbiology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 288

Candida albicans interactions with epithelial cells and mucosal immunity

Naglik, J. R., Moyes, D. L., Wächtler, B., & Hube, B. (2011) · Microbes and Infection

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 277

Glycosylphosphatidylinositol-anchored Proteases of Candida albicans Target Proteins Necessary for Both Cellular Processes and Host-Pathogen Interactions

Albrecht, A., Felk, A., Pichova, I., Naglik, J. R., Schaller, M., de Groot, P., MacCallum, D., Odds, F. C., Schäfer, W., Klis, F., et al. (2006) · Journal of Biological Chemistry

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 270

Quantitative expression of the Candida albicans secreted aspartyl proteinase gene family in human oral and vaginal candidiasis

Naglik, J. R., Moyes, D., Makwana, J., Kanzaria, P., Tsichlaki, E., Weindl, G., Tappuni, A. R., Rodgers, C. A., Woodman, A. J., Challacombe, S. J., et al. (2008) · Microbiology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 253

Systemic Fungal Infections Caused by Candida Species: Epidemiology, Infection Process and Virulence Attributes

Mavor, A., Thewes, S., & Hube, B. (2005) · Current Drug Targets

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 252

Candida albicans-Epithelial Interactions: Dissecting the Roles of Active Penetration, Induced Endocytosis and Host Factors on the Infection Process

Wächtler, B., Citiulo, F., Jablonowski, N., Förster, S., Dalle, F., Schaller, M., Wilson, D., & Hube, B. (2012) · PLoS ONE

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 250

Candida albicans Scavenges Host Zinc via Pra1 during Endothelial Invasion

Citiulo, F., Jacobsen, I. D., Miramón, P., Schild, L., Brunke, S., Zipfel, P., Brock, M., Hube, B., & Wilson, D. (2012) · PLoS Pathogens

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 242

Two unlike cousins: Candida albicans and C . glabrata infection strategies

Brunke, S., & Hube, B. (2013) · Cellular Microbiology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 239

Stage‐specific gene expression of Candida albicans in human blood

Fradin, C., Kretschmar, M., Nichterlein, T., Gaillardin, C., D’Enfert, C., & Hube, B. (2003) · Molecular Microbiology

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 226

The Facultative Intracellular Pathogen Candida glabrata Subverts Macrophage Cytokine Production and Phagolysosome Maturation

Seider, K., Brunke, S., Schild, L., Jablonowski, N., Wilson, D., Majer, O., Barz, D., Haas, A., Kuchler, K., Schaller, M., et al. (2011) · The Journal of Immunology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 220

Secreted lipases of Candida albicans : cloning, characterisation and expression analysis of a new gene family with at least ten members

Hube, B., Stehr, F., Bossenz, M., Mazur, A., Kretschmar, M., & Schäfer, W. (2000) · Archives of Microbiology

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 212

Candida albicans-Induced Epithelial Damage Mediates Translocation through Intestinal Barriers

Allert, S., Förster, T. M., Svensson, C.-M., Richardson, J. P., Pawlik, T., Hebecker, B., Rudolphi, S., Juraschitz, M., Schaller, M., Blagojevic, M., et al. (2018) · mBio

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 208

Candida albicans iron acquisition within the host

Almeida, R. S., Wilson, D., & Hube, B. (2009) · FEMS Yeast Research

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 199

Systematic Phenotyping of a Large-Scale Candida glabrata Deletion Collection Reveals Novel Antifungal Tolerance Genes

Schwarzmüller, T., Ma, B., Hiller, E., Istel, F., Tscherner, M., Brunke, S., Ames, L., Firon, A., Green, B., Cabral, V., et al. (2014) · PLoS Pathogens

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 191