Hube, Bernhard

Metabolism in fungal pathogenesis

Ene, I. V., Brunke, S., Brown, A. J. P., & Hube, B. (2014) · Cold Spring Harbor Perspectives in Medicine

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 169

Interaction of pathogenic yeasts with phagocytes: survival, persistence and escape.

Seider, K., Heyken, A., Lüttich, A., Miramón, P., & Hube, B. (2010) · Current Opinion in Microbiology

Fungal Infections and StudiesAntifungal resistance and susceptibility

Cited by 167

Molecular analysis of CaMnt1p, a mannosyl transferase important for adhesion and virulence of Candida albicans

Buurman, E. T., Westwater, C., Hube, B., Brown, A. J. P., Odds, F. C., & Gow, N. A. R. (1998) · Proceedings of the National Academy of Sciences

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 146

In vivo and ex vivo comparative transcriptional profiling of invasive and non‐invasive Candida albicans isolates identifies genes associated with tissue invasion

Thewes, S., Kretschmar, M., Park, H., Schaller, M., Filler, S. G., & Hube, B. (2007) · Molecular Microbiology

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 140

Identifying infection-associated genes of Candida albicans in the postgenomic era

Wilson, D., Thewes, S., Zakikhany, K., Fradin, C., Albrecht, A., Almeida, R., Brunke, S., Grosse, K., Martin, R., Mayer, F., et al. (2009) · FEMS Yeast Research

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 115

Exposure of Candida albicans to antifungal agents affects expression of SAP2 and SAP9 secreted proteinase genes

Copping, V. M. S., Barelle, C. J., Hube, B., Gow, N. A. R., Brown, A. J. P., & Odds, F. C. (2005) · Journal of Antimicrobial Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 113

Expression analysis of the lipase gene family during experimental infections and in patient samples

STEHR, F., FELK, A., GACSER, A., KRETSCHMAR, M., MAHNS, B., NEUBER, K., HUBE, B., & SCHAFER, W. (2004) · FEMS Yeast Research

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 105

Proteolytic Cleavage of Covalently Linked Cell Wall Proteins by Candida albicans Sap9 and Sap10

Schild, L., Heyken, A., de Groot, P. W. J., Hiller, E., Mock, M., de Koster, C., Horn, U., Rupp, S., & Hube, B. (2011) · Eukaryotic Cell

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 104

Candida pathogens induce protective mitochondria-associated type I interferon signalling and a damage-driven response in vaginal epithelial cells

Pekmezovic, M., Hovhannisyan, H., Gresnigt, M. S., Iracane, E., Oliveira-Pacheco, J., Siscar-Lewin, S., Seemann, E., Qualmann, B., Kalkreuter, T., Müller, S., et al. (2021) · Nature Microbiology

Antifungal resistance and susceptibilityinterferon and immune responses

Cited by 96

Immune evasion, stress resistance, and efficient nutrient acquisition are crucial for intracellular survival of Candida glabrata within macrophages

Seider, K., Gerwien, F., Kasper, L., Allert, S., Brunke, S., Jablonowski, N., Schwarzmüller, T., Barz, D., Rupp, S., Kuchler, K., et al. (2014) · Eukaryotic Cell

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 91

The Candida albicans-Specific Gene EED1 Encodes a Key Regulator of Hyphal Extension

Martin, R., Moran, G. P., Jacobsen, I. D., Heyken, A., Domey, J., Sullivan, D. J., Kurzai, O., & Hube, B. (2011) · PLoS ONE

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 85

Keeping Candida commensal: how lactobacilli antagonize pathogenicity of Candida albicans in an in vitro gut model

Graf, K., Last, A., Gratz, R., Allert, S., Linde, S., Westermann, M., Gröger, M., Mosig, A. S., Gresnigt, M. S., & Hube, B. (2019) · Disease Models & Mechanisms

Antifungal resistance and susceptibilityProbiotics and Fermented Foods

Cited by 83

In vivo imaging of disseminated murine Candida albicans infection reveals unexpected host sites of fungal persistence during antifungal therapy

Jacobsen, I. D., Lüttich, A., Kurzai, O., Hube, B., & Brock, M. (2014) · Journal of Antimicrobial Chemotherapy

Antifungal resistance and susceptibilityFungal Infections and Studies

Cited by 73

Zinc Limitation Induces a Hyper-Adherent Goliath Phenotype in Candida albicans

Malavia, D., Lehtovirta-Morley, L. E., Alamir, O., Weiß, E., Gow, N. A. R., Hube, B., & Wilson, D. (2017) · Frontiers in Microbiology

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 66

From environmental adaptation to host survival: Attributes that mediate pathogenicity of Candida auris

Allert, S., Schulz, D., Kämmer, P., Großmann, P., Wolf, T., Schäuble, S., Panagiotou, G., Brunke, S., & Hube, B. (2022) · Virulence

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 66

Secreted Aspartyl Proteinases and Interactions of Candida albicans with Human Endothelial Cells

Ibrahim, A. S., Filler, S. G., Sanglard, D., Edwards, J. E., & Hube, B. (1998) · Infection and Immunity

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 62

Antifungal defense of probiotic Lactobacillus rhamnosus GG is mediated by blocking adhesion and nutrient depletion

Mailänder-Sánchez, D., Braunsdorf, C., Grumaz, C., Müller, C., Lorenz, S., Stevens, P., Wagener, J., Hebecker, B., Hube, B., Bracher, F., et al. (2017) · PLoS ONE

Probiotics and Fermented FoodsAntifungal resistance and susceptibility

Cited by 59

Identification of Candida glabrata Genes Involved in pH Modulation and Modification of the Phagosomal Environment in Macrophages

Kasper, L., Seider, K., Gerwien, F., Allert, S., Brunke, S., Schwarzmüller, T., Ames, L., Zubiria-Barrera, C., Mansour, M. K., Becken, U., et al. (2014) · PLoS ONE

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 59

A novel hybrid iron regulation network combines features from pathogenic and nonpathogenic yeasts

Gerwien, F., Safyan, A., Wisgott, S., Hille, F., Kaemmer, P., Linde, J., Brunke, S., Kasper, L., & Hube, B. (2016) · mBio

Fungal and yeast genetics researchFungal Infections and Studies

Cited by 47

The Glycosylphosphatidylinositol-Anchored Protease Sap9 Modulates the Interaction of Candida albicans with Human Neutrophils

Hornbach, A., Heyken, A., Schild, L., Hube, B., Löffler, J., & Kurzai, O. (2009) · Infection and Immunity

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 47

Candida glabrata tryptophan‐based pigment production via the Ehrlich pathway

Brunke, S., Seider, K., Almeida, R. S., Heyken, A., Fleck, C. B., Brock, M., Barz, D., Rupp, S., & Hube, B. (2010) · Molecular Microbiology

Fungal and yeast genetics researchMicrobial Metabolism and Applications

Cited by 37

Transient mitochondria dysfunction confers fungal cross-resistance against phagocytic killing and fluconazole

Siscar-Lewin, S., Gabaldón, T., Aldejohann, A. M., Kurzai, O., Hube, B., & Brunke, S. (2021) · mBio

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 36

The fungal pathogen Candida glabrata does not depend on surface ferric reductases for iron acquisition

Gerwien, F., Safyan, A., Wisgott, S., Brunke, S., Kasper, L., & Hube, B. (2017) · Frontiers in Microbiology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 33

B Cell Recognition of Candida albicans Hyphae via TLR 2 Promotes IgG1 and IL-6 Secretion for TH17 Differentiation

Ferreira-Gomes, M., Wich, M., Böde, S., Hube, B., Jacobsen, I. D., & Jungnickel, B. (2021) · Frontiers in Immunology

Immune Response and InflammationAntifungal resistance and susceptibility

Cited by 29