Zerial, Marino

Rab proteins as membrane organizers

Zerial, M., & McBride, H. (2001) · Nature Reviews Molecular Cell Biology

Cellular transport and secretionExtracellular vesicles in disease

Cited by 3,381

Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape

Gilleron, J., Querbes, W., Zeigerer, A., Borodovsky, A., Marsico, G., Schubert, U., Manygoats, K., Seifert, S., Andree, C., Stöter, M., et al. (2013) · Nature Biotechnology

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 1,681

Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms

Akinc, A., Querbes, W., De, S., Qin, J., Frank-Kamenetsky, M., Jayaprakash, K. N., Jayaraman, M., Rajeev, K. G., Cantley, W. L., Dorkin, J. R., et al. (2010) · Molecular Therapy

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 1,261

Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments

Chavrier, P., Parton, R. G., Hauri, H. P., Simons, K., & Zerial, M. (1990) · Cell

Cellular transport and secretionCalcium signaling and nucleotide metabolism

Cited by 1,166

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

Simonsen, A., Lippe, R., Christoforidis, S., Gaullier, J.-M., Brech, A., Callaghan, J., Toh, B.-H., Murphy, C., Zerial, M., & Stenmark, H. (1998) · Nature

Cellular transport and secretionCalcium signaling and nucleotide metabolism

Cited by 1,133

Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis.

Stenmark, H., Parton, R. G., Steele‐Mortimer, O., Lütcke, A., Gruenberg, J., & Zerial, M. (1994) · The EMBO Journal

Cellular transport and secretionProtein Kinase Regulation and GTPase Signaling

Cited by 968

The mosaic genome of warm-blooded vertebrates

Bernardi, G., Olofsson, B., Filipski, J., Zerial, M., Salinas, J., Cuny, G., Meunier-Rotival, M., & Rodier, F. (1985) · Science

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 875

The Rab5 effector EEA1 is a core component of endosome docking

Christoforidis, S., McBride, H. M., Burgoyne, R. D., & Zerial, M. (1999) · Nature

Cellular transport and secretionAutophagy in Disease and Therapy

Cited by 854

Identification of the Switch in Early-to-Late Endosome Transition

Poteryaev, D., Datta, S., Ackema, K., Zerial, M., & Spang, A. (2010) · Cell

Cellular transport and secretionAutophagy in Disease and Therapy

Cited by 752

Rab Proteins and the Compartmentalization of the Endosomal System

Wandinger-Ness, A., & Zerial, M. (2014) · Cold Spring Harbor Perspectives in Biology

Cellular transport and secretionCalcium signaling and nucleotide metabolism

Cited by 586

Oligomeric Complexes Link Rab5 Effectors with NSF and Drive Membrane Fusion via Interactions between EEA1 and Syntaxin 13

McBride, H. M., Rybin, V., Murphy, C., Giner, A., Teasdale, R., & Zerial, M. (1999) · Cell

Cellular transport and secretionAutophagy in Disease and Therapy

Cited by 520

A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity

Bramsen, J. B., Laursen, M. B., Nielsen, A. F., Hansen, T. B., Bus, C., Langkjær, N., Babu, B. R., Højland, T., Abramov, M., Van Aerschot, A., et al. (2009) · Nucleic Acids Research

RNA Interference and Gene DeliveryDNA and Nucleic Acid Chemistry

Cited by 369

Rab5 is necessary for the biogenesis of the endolysosomal system in vivo

Zeigerer, A., Gilleron, J., Bogorad, R. L., Marsico, G., Nonaka, H., Seifert, S., Epstein-Barash, H., Kuchimanchi, S., Peng, C. G., Ruda, V. M., et al. (2012) · Nature

Cellular transport and secretionAutophagy in Disease and Therapy

Cited by 362

Three-Dimensional spatially resolved geometrical and functional models of human liver tissue reveal new aspects of NAFLD progression

Segovia-Miranda, F., Morales-Navarrete, H., Kücken, M., Moser, V., Seifert, S., Repnik, U., Rost, F., Brosch, M., Hendricks, A., Hinz, S., et al. (2019) · Nature Medicine

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 109

A versatile pipeline for the multi-scale digital reconstruction and quantitative analysis of 3D tissue architecture

Morales-Navarrete, H., Segovia-Miranda, F., Klukowski, P., Meyer, K., Nonaka, H., Marsico, G., Chernykh, M., Kalaidzidis, A., Zerial, M., & Kalaidzidis, Y. (2015) · eLife

Cell Image Analysis TechniquesMedical Image Segmentation Techniques

Cited by 98

A Predictive 3D Multi-Scale Model of Biliary Fluid Dynamics in the Liver Lobule

Meyer, K., Ostrenko, O., Bourantas, G., Morales-Navarrete, H., Porat-Shliom, N., Segovia-Miranda, F., Nonaka, H., Ghaemi, A., Verbavatz, J.-M., Brusch, L., et al. (2017) · Cell Systems

Liver physiology and pathologyDrug Transport and Resistance Mechanisms

Cited by 91

SnapShot: Mammalian Rab Proteins in Endocytic Trafficking

Galvez, T., Gilleron, J., Zerial, M., & O'Sullivan, G. A. (2012) · Cell

Cellular transport and secretionCalcium signaling and nucleotide metabolism

Cited by 71

Mouse liver assembloids model periportal architecture and biliary fibrosis

Dowbaj, A. M., Sljukic, A., Niksic, A., Landerer, C., Delpierre, J., Yang, H., Lahree, A., Kühn, A. C., Beers, D., Byrne, H. M., et al. (2025) · Nature

Liver physiology and pathologyLiver Diseases and Immunity

Cited by 40

Bile canaliculi remodeling activates YAP via the actin cytoskeleton during liver regeneration

Meyer, K., Morales‐Navarrete, H., Seifert, S., Wilsch‐Braeuninger, M., Dahmen, U., Tanaka, E. M., Brusch, L., Kalaidzidis, Y., & Zerial, M. (2020) · Molecular Systems Biology

Hippo pathway signaling and YAP/TAZLiver physiology and pathology

Cited by 39