Levine, Beth

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

He, C., Bassik, M. C., Moresi, V., Sun, K., Wei, Y., Zou, Z., An, Z., Loh, J., Fisher, J., Sun, Q., et al. (2012) · Nature

Autophagy in Disease and TherapyMetabolism, Diabetes, and Cancer

Cited by 1,136

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

Galluzzi, L., Bravo-San Pedro, J. M., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Alnemri, E. S., Altucci, L., Andrews, D., Annicchiarico-Petruzzelli, M., et al. (2015) · Cell Death & Differentiation

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 1,002

HSV-1 ICP34.5 Confers Neurovirulence by Targeting the Beclin 1 Autophagy Protein

Orvedahl, A., Alexander, D., Tallóczy, Z., Sun, Q., Wei, Y., Zhang, W., Burns, D., Leib, D. A., & Levine, B. (2007) · Cell Host & Microbe

Herpesvirus Infections and TreatmentsAutophagy in Disease and Therapy

Cited by 857

Metabolic control of autophagy

Galluzzi, L., Pietrocola, F., Levine, B., & Kroemer, G. (2014) · Cell

Autophagy in Disease and TherapyMetabolism, Diabetes, and Cancer

Cited by 855

Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles

Galluzzi, L., Bravo-San Pedro, J. M., Levine, B., Green, D. R., & Kroemer, G. (2017) · Nature Reviews Drug Discovery

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 842

Identification of a candidate therapeutic autophagy-inducing peptide

Shoji-Kawata, S., Sumpter, R., Leveno, M., Campbell, G. R., Zou, Z., Kinch, L., Wilkins, A. D., Sun, Q., Pallauf, K., MacDuff, D., et al. (2013) · Nature

Autophagy in Disease and TherapyRNA Interference and Gene Delivery

Cited by 760

Akt-Mediated Regulation of Autophagy and Tumorigenesis Through Beclin 1 Phosphorylation

Wang, R. C., Wei, Y., An, Z., Zou, Z., Xiao, G., Bhagat, G., White, M., Reichelt, J., & Levine, B. (2012) · Science

Autophagy in Disease and TherapyPI3K/AKT/mTOR signaling in cancer

Cited by 728

Disruption of the beclin 1–BCL2 autophagy regulatory complex promotes longevity in mice

Fernández, Á. F., Sebti, S., Wei, Y., Zou, Z., Shi, M., McMillan, K. L., He, C., Ting, T., Liu, Y., Chiang, W.-C., et al. (2018) · Nature

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

Cited by 630

Autosis is a Na + ,K + -ATPase–regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia–ischemia

Liu, Y., Shoji-Kawata, S., Sumpter, R. M., Wei, Y., Ginet, V., Zhang, L., Posner, B., Tran, K. A., Green, D. R., Xavier, R. J., et al. (2013) · Proceedings of the National Academy of Sciences

Autophagy in Disease and TherapyCell death mechanisms and regulation

Cited by 607

Autophagy balances inflammation in innate immunity

Deretic, V., & Levine, B. (2018) · Autophagy

Autophagy in Disease and TherapyInflammasome and immune disorders

Cited by 563

Autophagy Protects against Sindbis Virus Infection of the Central Nervous System

Orvedahl, A., MacPherson, S., Sumpter, R., Tallóczy, Z., Zou, Z., & Levine, B. (2010) · Cell Host & Microbe

Autophagy in Disease and TherapyMosquito-borne diseases and control

Cited by 558

Caloric restriction mimetics enhance anticancer immunosurveillance

Pietrocola, F., Pol, J., Vacchelli, E., Rao, S., Enot, D. P., Baracco, E. E., Levesque, S., Castoldi, F., Jacquelot, N., Yamazaki, T., et al. (2016) · Cancer Cell

Autophagy in Disease and TherapyDietary Effects on Health

Cited by 542

Dual Role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation

Wei, Y., Sinha, S. C., & Levine, B. (2008) · Autophagy

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 424

Autophagy and the cell biology of age-related disease

Leidal, A. M., Levine, B., & Debnath, J. (2018) · Nature Cell Biology

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 424

Autophagy is Required for Dietary Restriction-Mediated Life Span Extension in C. elegans

Jia, K., & Levine, B. (2007) · Autophagy

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

Cited by 341

Fanconi Anemia Proteins Function in Mitophagy and Immunity

Sumpter, R., Sirasanagandla, S., Fernández, Á. F., Wei, Y., Dong, X., Franco, L., Zou, Z., Marchal, C., Lee, M. Y., Clapp, D. W., et al. (2016) · Cell

Autophagy in Disease and TherapyDNA Repair Mechanisms

Cited by 250

A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease

Rocchi, A., Yamamoto, S., Ting, T., Fan, Y., Sadleir, K., Wang, Y., Zhang, W., Huang, S., Levine, B., Vassar, R., et al. (2017) · PLOS Genetics

Alzheimer's disease research and treatmentsAutophagy in Disease and Therapy

Cited by 166

Upregulation of Rubicon promotes autosis during myocardial ischemia/reperfusion injury

Nah, J., Zhai, P., Huang, C.-Y., Fernández, Á. F., Mareedu, S., Levine, B., & Sadoshima, J. (2020) · Journal of Clinical Investigation

Autophagy in Disease and TherapyCardiac Ischemia and Reperfusion

Cited by 150

An increase in LRRK2 suppresses autophagy and enhances Dectin-1–induced immunity in a mouse model of colitis

Takagawa, T., Kitani, A., Fuss, I., Levine, B., Brant, S. R., Peter, I., Tajima, M., Nakamura, S., & Strober, W. (2018) · Science Translational Medicine

Inflammatory Bowel DiseaseAutophagy in Disease and Therapy

Cited by 145

Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis

Nassif, M., Valenzuela, V., Rojas-Rivera, D., Vidal, R., Matus, S., Castillo, K., Fuentealba, Y., Kroemer, G., Levine, B., & Hetz, C. (2014) · Autophagy

Amyotrophic Lateral Sclerosis ResearchAutophagy in Disease and Therapy

Cited by 100