Schuman, Erin M.

Long-Lasting Neurotrophin-Induced Enhancement of Synaptic Transmission in the Adult Hippocampus

Kang, H., & Schuman, E. M. (1995) · Science

Nerve injury and regenerationNeuroscience and Neuropharmacology Research

Cited by 1,354

Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity

You, X., Vlatkovic, I., Babic, A., Will, T., Epstein, I., Tushev, G., Akbalik, G., Wang, M., Glock, C., Quedenau, C., et al. (2015) · Nature Neuroscience

Circular RNAs in diseasesRNA Research and Splicing

Cited by 1,149

Selective identification of newly synthesized proteins in mammalian cells using bioorthogonal noncanonical amino acid tagging (BONCAT)

Dieterich, D. C., Link, A. J., Graumann, J., Tirrell, D. A., & Schuman, E. M. (2006) · Proceedings of the National Academy of Sciences

Advanced Proteomics Techniques and ApplicationsClick Chemistry and Applications

Cited by 874

A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus

Tang, S. J., Reis, G., Kang, H., Gingras, A.-C., Sonenberg, N., & Schuman, E. M. (2002) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchPI3K/AKT/mTOR signaling in cancer

Cited by 734

The local transcriptome in the synaptic neuropil revealed by deep sequencing and high-resolution imaging

Cajigas, I. J., Tushev, G., Will, T. J., tom Dieck, S., Fuerst, N., & Schuman, E. M. (2012) · Neuron

Neuroscience and Neuropharmacology ResearchRNA Research and Splicing

Cited by 709

Miniature Neurotransmission Stabilizes Synaptic Function via Tonic Suppression of Local Dendritic Protein Synthesis

Sutton, M. A., Ito, H. T., Cressy, P., Kempf, C., Woo, J. C., & Schuman, E. M. (2006) · Cell

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 633

Human memory strength is predicted by theta-frequency phase-locking of single neurons

Rutishauser, U., Ross, I. B., Mamelak, A. N., & Schuman, E. M. (2010) · Nature

Memory and Neural MechanismsNeural dynamics and brain function

Cited by 622

Dynamic visualization of local protein synthesis in hippocampal neurons

Aakalu, G., Smith, W. B., Nguyen, N., Jiang, C., & Schuman, E. M. (2001) · Neuron

Neuroscience and Neuropharmacology ResearchRNA and protein synthesis mechanisms

Cited by 611

Ubiquitin, the proteasome and protein degradation in neuronal function and dysfunction

Tai, H.-C., & Schuman, E. M. (2008) · Nature Reviews Neuroscience

Ubiquitin and proteasome pathwaysAutophagy in Disease and Therapy

Cited by 532

The Central Dogma Decentralized: New Perspectives on RNA Function and Local Translation in Neurons

Holt, C. E., & Schuman, E. M. (2013) · Neuron

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 525

Neurotrophins and Time: Different Roles for TrkB Signaling in Hippocampal Long-Term Potentiation

Kang, H., Welcher, A. A., Shelton, D., & Schuman, E. M. (1997) · Neuron

Neuroscience and Neuropharmacology ResearchNerve injury and regeneration

Cited by 481

Local protein synthesis is a ubiquitous feature of neuronal pre- and postsynaptic compartments

Hafner, A.-S., Donlin-Asp, P. G., Leitch, B., Herzog, E., & Schuman, E. M. (2019) · Science

Neuroscience and Neuropharmacology ResearchRNA and protein synthesis mechanisms

Cited by 431

Alternative 3′ UTRs modify the localization, regulatory potential, stability, and plasticity of mRNAs in neuronal compartments

Tushev, G., Glock, C., Heumüller, M., Biever, A., Jovanovic, M., & Schuman, E. M. (2018) · Neuron

RNA Research and SplicingNeuroscience and Neuropharmacology Research

Cited by 377

Activity-dependent dynamics and sequestration of proteasomes in dendritic spines

Bingol, B., & Schuman, E. M. (2006) · Nature

Ubiquitin and proteasome pathwaysNeuroscience and Neuropharmacology Research

Cited by 347

Postsynaptic Decoding of Neural Activity: eEF2 as a Biochemical Sensor Coupling Miniature Synaptic Transmission to Local Protein Synthesis

Sutton, M. A., Taylor, A. M., Ito, H. T., Pham, A., & Schuman, E. M. (2007) · Neuron

Neuroscience and Neuropharmacology ResearchRNA and protein synthesis mechanisms

Cited by 274

Monosomes actively translate synaptic mRNAs in neuronal processes

Biever, A., Glock, C., Tushev, G., Ciirdaeva, E., Langer, J. D., & Schuman, E. M. (2019) · Science

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 271

Dopaminergic stimulation of local protein synthesis enhances surface expression of GluR1 and synaptic transmission in hippocampal neurons

Smith, W. B., Starck, S. R., Roberts, R. W., & Schuman, E. M. (2005) · Neuron

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 252

Local and global influences on protein turnover in neurons and glia

Dörrbaum, A. R., Kochen, L., Langer, J. D., & Schuman, E. M. (2018) · eLife

Ubiquitin and proteasome pathwaysAdvanced Proteomics Techniques and Applications

Cited by 249

Synaptic regulation of translation of dendritic mRNAs

Schuman, E. M., Dynes, J. L., & Steward, O. (2006) · The Journal of Neuroscience

RNA and protein synthesis mechanismsNeuroscience and Neuropharmacology Research

Cited by 230

Cell-type-specific metabolic labeling of nascent proteomes in vivo

Alvarez-Castelao, B., Schanzenbächer, C. T., Hanus, C., Glock, C., tom Dieck, S., Dörrbaum, A. R., Bartnik, I., Nassim-Assir, B., Ciirdaeva, E., Mueller, A., et al. (2017) · Nature Biotechnology

Advanced Proteomics Techniques and ApplicationsClick Chemistry and Applications

Cited by 219

Calcium-dependent dynamics of cadherin interactions at cell–cell junctions

Kim, S. A., Tai, C.-Y., Mok, L.-P., Mosser, E. A., & Schuman, E. M. (2011) · Proceedings of the National Academy of Sciences

Cell Adhesion Molecules ResearchCellular Mechanics and Interactions

Cited by 170

Neuronal ribosomes exhibit dynamic and context-dependent exchange of ribosomal proteins

Fusco, C. M., Desch, K., Dörrbaum, A. R., Wang, M., Staab, A., Chan, I. C. W., Vail, E., Villeri, V., Langer, J. D., & Schuman, E. M. (2021) · Nature Communications

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 157

The proteomic landscape of synaptic diversity across brain regions and cell types

van Oostrum, M., Blok, T. M., Giandomenico, S. L., tom Dieck, S., Tushev, G., Fürst, N., Langer, J. D., & Schuman, E. M. (2023) · Cell

Neuroscience and Neuropharmacology ResearchAdvanced Proteomics Techniques and Applications

Cited by 135

The Regulation of Synaptic Protein Turnover

Alvarez-Castelao, B., & Schuman, E. M. (2015) · Journal of Biological Chemistry

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 110