Shepherd, Jason D.

Triple-Transgenic Model of Alzheimer’s Disease with Plaques and Tangles

Oddo, S., Caccamo, A., Shepherd, J. D., Murphy, M. P., Golde, T. E., Kayed, R., Metherate, R., Mattson, M. P., Akbari, Y., & LaFerla, F. M. (2003) · Neuron

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 4,126

The cell biology of synaptic plasticity: AMPA receptor trafficking

Shepherd, J. D., & Huganir, R. L. (2007) · Annual Review of Cell and Developmental Biology

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 978

Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking

Chowdhury, S., Shepherd, J. D., Okuno, H., Lyford, G., Petralia, R. S., Plath, N., Kuhl, D., Huganir, R. L., & Worley, P. F. (2006) · Neuron

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 792

Arc/Arg3.1 Mediates Homeostatic Synaptic Scaling of AMPA Receptors

Shepherd, J. D., Rumbaugh, G., Wu, J., Chowdhury, S., Plath, N., Kuhl, D., Huganir, R. L., & Worley, P. F. (2006) · Neuron

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 779

Elongation Factor 2 and Fragile X Mental Retardation Protein Control the Dynamic Translation of Arc/Arg3.1 Essential for mGluR-LTD

Park, S., Park, J. M., Kim, S., Kim, J.-A., Shepherd, J. D., Smith-Hicks, C. L., Chowdhury, S., Kaufmann, W., Kuhl, D., Ryazanov, A. G., et al. (2008) · Neuron

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 516

New views of Arc, a master regulator of synaptic plasticity

Shepherd, J. D., & Bear, M. F. (2011) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 481

The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer

Pastuzyn, E. D., Day, C. E., Kearns, R. B., Kyrke-Smith, M., Taibi, A. V., McCormick, J., Yoder, N., Belnap, D. M., Erlendsson, S., Morado, D. R., et al. (2018) · Cell

RNA Research and SplicingChromosomal and Genetic Variations

Cited by 213

Loss of Arc renders the visual cortex impervious to the effects of sensory experience or deprivation

McCurry, C. L., Shepherd, J. D., Tropea, D., Wang, K. H., Bear, M. F., & Sur, M. (2010) · Nature Neuroscience

Visual perception and processing mechanismsNeuroscience and Neuropharmacology Research

Cited by 159

Three-dimensional genome restructuring across timescales of activity-induced neuronal gene expression

Beagan, J. A., Pastuzyn, E. D., Fernandez, L. R., Guo, M. H., Feng, K., Titus, K. R., Chandrashekar, H., Shepherd, J. D., & Phillips-Cremins, J. E. (2020) · Nature Neuroscience

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 143

The microbiota protects from viral-induced neurologic damage through microglia-intrinsic TLR signaling

Brown, D. G., Soto, R., Yandamuri, S., Stone, C., Dickey, L., Gomes-Neto, J. C., Pastuzyn, E. D., Bell, R., Petersen, C., Buhrke, K., et al. (2019) · eLife

Neuroinflammation and Neurodegeneration MechanismsImmune Response and Inflammation

Cited by 60

Memory, plasticity and sleep - A role for calcium permeable AMPA receptors?

Shepherd, J. D. (2012) · Frontiers in Molecular Neuroscience

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 49