Boothman, David A.

Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems

Nasongkla, N., Bey, E., Ren, J., Ai, H., Khemtong, C., Guthi, J. S., Chin, S.-F., Sherry, A. D., Boothman, D. A., & Gao, J. (2006) · Nano Letters

Nanoparticle-Based Drug DeliveryNanoplatforms for cancer theranostics

Cited by 1,238

NAD(P)H:Quinone Oxidoreductase Activity Is the Principal Determinant of β-Lapachone Cytotoxicity

Pink, J. J., Planchon, S. M., Tagliarino, C., Varnes, M. E., Siegel, D., & Boothman, D. A. (2000) · Journal of Biological Chemistry

Bioactive Compounds and Antitumor AgentsGenomics, phytochemicals, and oxidative stress

Cited by 376

β-Lapachone-containing PEG–PLA polymer micelles as novel nanotherapeutics against NQO1-overexpressing tumor cells

Blanco, E., Bey, E. A., Dong, Y., Weinberg, B. D., Sutton, D. M., Boothman, D. A., & Gao, J. (2007) · Journal of Controlled Release

Nanoparticle-Based Drug DeliveryBioactive Compounds and Antitumor Agents

Cited by 165

Intracellular Clusterin Inhibits Mitochondrial Apoptosis by Suppressing p53-Activating Stress Signals and Stabilizing the Cytosolic Ku70-Bax Protein Complex

Trougakos, I. P., Lourda, M., Antonelou, M. H., Kletsas, D., Gorgoulis, V. G., Papassideri, I. S., Zou, Y., Margaritis, L. H., Boothman, D. A., & Gonos, E. S. (2009) · Clinical Cancer Research

Clusterin in disease pathologyCell death mechanisms and regulation

Cited by 160

Galactic cosmic ray simulation at the NASA Space Radiation Laboratory

Norbury, J. W., Schimmerling, W., Slaba, T. C., Azzam, E. I., Badavi, F. F., Baiocco, G., Benton, E., Bindi, V., Blakely, E. A., Blattnig, S. R., et al. (2016) · Life Sciences in Space Research

Radiation Therapy and DosimetryEffects of Radiation Exposure

Cited by 155

Dual Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Blockade Is an Effective Radiosensitizing Strategy for the Treatment of Non–Small Cell Lung Cancer Harboring K-RAS Mutations

Konstantinidou, G., Bey, E. A., Rabellino, A., Schuster, K., Maira, M. S., Gazdar, A. F., Amici, A., Boothman, D. A., & Scaglioni, P. P. (2009) · Cancer Research

PI3K/AKT/mTOR signaling in cancerLung Cancer Treatments and Mutations

Cited by 142

TGF-β1–induced expression of human Mdm2 correlates with late-stage metastatic breast cancer

Araki, S., Eitel, J. A., Batuello, C. N., Bijangi-Vishehsaraei, K., Xie, X.-J., Danielpour, D., Pollok, K. E., Boothman, D. A., & Mayo, L. D. (2010) · Journal of Clinical Investigation

TGF-β signaling in diseasesCancer-related Molecular Pathways

Cited by 133

Bax-inhibiting peptides derived from Ku70 and cell-penetrating pentapeptides

Gomez, J. A., Gama, V., Yoshida, T., Sun, W., Hayes, P., Leskov, K., Boothman, D., & Matsuyama, S. (2007) · Biochemical Society Transactions

Cell death mechanisms and regulationRNA Interference and Gene Delivery

Cited by 97

Focal Adhesion Kinase Regulates the DNA Damage Response and Its Inhibition Radiosensitizes Mutant KRAS Lung Cancer

Tang, K.-J., Constanzo, J. D., Venkateswaran, N., Melegari, M., Ilcheva, M., Morales, J. C., Skoulidis, F., Heymach, J. V., Boothman, D. A., & Scaglioni, P. P. (2016) · Clinical Cancer Research

DNA Repair MechanismsProtein Kinase Regulation and GTPase Signaling

Cited by 91

Personalized Genome-Scale Metabolic Models Identify Targets of Redox Metabolism in Radiation-Resistant Tumors

Lewis, J. E., Forshaw, T. E., Boothman, D. A., Furdui, C. M., & Kemp, M. L. (2021) · Cell Systems

Cancer, Hypoxia, and MetabolismMicrobial Metabolic Engineering and Bioproduction

Cited by 61

Interleukin-6 affects cell death escaping mechanisms acting on Bax-Ku70-Clusterin interactions in human colon cancer progression

Pucci, S., Mazzarelli, P., Sesti, F., Boothman, D. A., & Spagnoli, L. G. (2009) · Cell Cycle

Cell death mechanisms and regulationClusterin in disease pathology

Cited by 46