Kosik, Kenneth S.

MicroRNA-21 Is an Antiapoptotic Factor in Human Glioblastoma Cells

Chan, J. A., Krichevsky, A. M., & Kosik, K. S. (2005) · Cancer Research

MicroRNA in disease regulationCancer-related molecular mechanisms research

Cited by 2,557

Ubiquitination of a new form of α-synuclein by parkin from human brain: implications for Parkinson's disease

Shimura, H., Schlossmacher, M. G., Hattori, N., Frosch, M. P., Trockenbacher, A., Schneider, R., Mizuno, Y., Kosik, K. S., & Selkoe, D. J. (2001) · Science

Parkinson's Disease Mechanisms and TreatmentsUbiquitin and proteasome pathways

Cited by 1,053

A microRNA array reveals extensive regulation of microRNAs during brain development

KRICHEVSKY, A. M., KING, K. S., DONAHUE, C. P., KHRAPKO, K., & KOSIK, K. S. (2003) · RNA

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 1,040

MicroRNA-21 Targets a Network of Key Tumor-Suppressive Pathways in Glioblastoma Cells

Papagiannakopoulos, T., Shapiro, A., & Kosik, K. S. (2008) · Cancer Research

MicroRNA in disease regulationCancer-related molecular mechanisms research

Cited by 705

Specific microRNAs modulate embryonic stem cell-derived neurogenesis.

Krichevsky, A. M., Sonntag, K.-C., Isacson, O., & Kosik, K. S. (2006) · Stem Cells

Neurogenesis and neuroplasticity mechanismsMicroRNA in disease regulation

Cited by 692

Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer’s Disease

Wesseling, H., Mair, W., Kumar, M., Schlaffner, C. N., Tang, S., Beerepoot, P., Fatou, B., Guise, A. J., Cheng, L., Takeda, S., et al. (2020) · Cell

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 688

Resistance to autosomal dominant Alzheimer’s disease in an APOE3 Christchurch homozygote: a case report

Arboleda-Velasquez, J. F., Lopera, F., O’Hare, M., Delgado-Tirado, S., Marino, C., Chmielewska, N., Saez-Torres, K. L., Amarnani, D., Schultz, A. P., Sperling, R. A., et al. (2019) · Nature Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 598

Synaptic dysregulation in a human iPS cell model of mental disorders

Wen, Z., Nguyen, H. N., Guo, Z., Lalli, M. A., Wang, X., Su, Y., Kim, N.-S., Yoon, K.-J., Shin, J., Zhang, C., et al. (2014) · Nature

Pluripotent Stem Cells ResearchSchizophrenia research and treatment

Cited by 549

Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study

Reiman, E. M., Quiroz, Y. T., Fleisher, A. S., Chen, K., Velez-Pardo, C., Jimenez-Del-Rio, M., Fagan, A. M., Shah, A. R., Alvarez, S., Arbelaez, A., et al. (2012) · The Lancet Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 541

LRP1 is a master regulator of tau uptake and spread

Rauch, J. N., Luna, G., Guzman, E., Audouard, M., Challis, C., Sibih, Y. E., Leshuk, C., Hernandez, I., Wegmann, S., Hyman, B. T., et al. (2020) · Nature

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 541

The microtubule binding domain of tau protein

Lee, G., Neve, R. L., & Kosik, K. S. (1989) · Neuron

Alzheimer's disease research and treatmentsMicrotubule and mitosis dynamics

Cited by 500

MicroRNA profiling of the murine hematopoietic system

Monticelli, S., Ansel, K. M., Xiao, C., Socci, N. D., Krichevsky, A. M., Thai, T.-H., Rajewsky, N., Marks, D. S., Sander, C., Rajewsky, K., et al. (2005) · Genome Biology

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 436

Neuritic pathology and dementia in alzheimer's disease

McKee, A. C., Kosik, K. S., & Kowall, N. W. (1991) · Annals of Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 358

The outer subventricular zone and primate-specific cortical complexification

Dehay, C., Kennedy, H., & Kosik, K. S. (2015) · Neuron

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 314

A Post-Synaptic Scaffold at the Origin of the Animal Kingdom

Sakarya, O., Armstrong, K. A., Adamska, M., Adamski, M., Wang, I.-F., Tidor, B., Degnan, B. M., Oakley, T. H., & Kosik, K. S. (2007) · PLoS ONE

Marine Invertebrate Physiology and EcologyNeuroscience and Neuropharmacology Research

Cited by 291

Identification of piRNAs in the central nervous system

Lee, E. J., Banerjee, S., Zhou, H., Jammalamadaka, A., Arcila, M., Manjunath, B. S., & Kosik, K. S. (2011) · RNA

Chromosomal and Genetic VariationsRNA Interference and Gene Delivery

Cited by 289

Overexpression of tau in a nonneuronal cell induces long cellular processes.

Knops, J., Kosik, K. S., Lee, G., Pardee, J. D., Cohen-Gould, L., & McConlogue, L. (1991) · The Journal of cell biology

Alzheimer's disease research and treatmentsMicrotubule and mitosis dynamics

Cited by 286

Heterogeneous dysregulation of microRNAs across the autism spectrum

Abu-Elneel, K., Liu, T., Gazzaniga, F. S., Nishimura, Y., Wall, D. P., Geschwind, D. H., Lao, K., & Kosik, K. S. (2008) · neurogenetics

Autism Spectrum Disorder ResearchMicroRNA in disease regulation

Cited by 271

Human neural tube morphogenesis in vitro by geometric constraints

Karzbrun, E., Khankhel, A. H., Megale, H. C., Glasauer, S. M. K., Wyle, Y., Britton, G., Warmflash, A., Kosik, K. S., Siggia, E. D., Shraiman, B. I., et al. (2021) · Nature

Developmental Biology and Gene RegulationCellular Mechanics and Interactions

Cited by 246

In vivo phosphorylation sites in fetal and adult rat tau

Watanabe, A., Hasegawa, M., Suzuki, M., Takio, K., Morishima-Kawashima, M., Titani, K., Arai, T., Kosik, K. S., & Ihara, Y. (1993) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsAdvanced Proteomics Techniques and Applications

Cited by 231

Tau Internalization is Regulated by 6-O Sulfation on Heparan Sulfate Proteoglycans (HSPGs)

Rauch, J. N., Chen, J. J., Sorum, A. W., Miller, G. M., Sharf, T., See, S. K., Hsieh-Wilson, L. C., Kampmann, M., & Kosik, K. S. (2018) · Scientific Reports

Alzheimer's disease research and treatmentsProteoglycans and glycosaminoglycans research

Cited by 211

A Quantitative Framework to Evaluate Modeling of Cortical Development by Neural Stem Cells

Stein, J. L., de la Torre-Ubieta, L., Tian, Y., Parikshak, N. N., Hernández, I. A., Marchetto, M. C., Baker, D. K., Lu, D., Hinman, C. R., Lowe, J. K., et al. (2014) · Neuron

Neurogenesis and neuroplasticity mechanismsPluripotent Stem Cells Research

Cited by 201

Apolipoprotein Eε4 modifies Alzheimer's disease onset in an E280A PS1 kindred

Pastor, P., Roe, C. M., Villegas, A., Bedoya, G., Chakraverty, S., García, G., Tirado, V., Norton, J., Ríos, S., Martínez, M., et al. (2003) · Annals of Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 194

Resilience to autosomal dominant Alzheimer’s disease in a Reelin-COLBOS heterozygous man

Lopera, F., Marino, C., Chandrahas, A. S., O’Hare, M., Villalba-Moreno, N. D., Aguillon, D., Baena, A., Sanchez, J. S., Vila-Castelar, C., Ramirez Gomez, L., et al. (2023) · Nature Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 192