Henikoff, Steven

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

Kumar, P., Henikoff, S., & Ng, P. C. (2009) · Nature Protocols

Genomics and Rare DiseasesGenomics and Phylogenetic Studies

Cited by 6,521

Amino acid substitution matrices from protein blocks.

Henikoff, S., & Henikoff, J. G. (1992) · Proceedings of the National Academy of Sciences

Genomics and Phylogenetic StudiesFractal and DNA sequence analysis

Cited by 6,218

CUT&Tag for efficient epigenomic profiling of small samples and single cells

Kaya-Okur, H. S., Wu, S. J., Codomo, C. A., Pledger, E. S., Bryson, T. D., Henikoff, J. G., Ahmad, K., & Henikoff, S. (2019) · Nature Communications

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 2,187

Comparative Genomics of the Eukaryotes

Rubin, G. M., Yandell, M. D., Wortman, J. R., Gabor, G. L., Miklos, Nelson, C. R., Hariharan, I. K., Fortini, M. E., Li, P. W., Apweiler, R., et al. (2000) · Science

Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks

Cited by 1,698

Regulation of nucleosome dynamics by histone modifications

Zentner, G. E., & Henikoff, S. (2013) · Nature Structural & Molecular Biology

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 923

Targeted in situ genome-wide profiling with high efficiency for low cell numbers

Skene, P. J., Henikoff, J. G., & Henikoff, S. (2018) · Nature Protocols

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 803

Histone H2A.Z and DNA methylation are mutually antagonistic chromatin marks

Zilberman, D., Coleman-Derr, D., Ballinger, T., & Henikoff, S. (2008) · Nature

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 593

Peak calling by Sparse Enrichment Analysis for CUT&RUN chromatin profiling

Meers, M. P., Tenenbaum, D., & Henikoff, S. (2019) · Epigenetics & Chromatin

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 556

Histone H3.3 is enriched in covalent modifications associated with active chromatin

McKittrick, E., Gafken, P. R., Ahmad, K., & Henikoff, S. (2004) · Proceedings of the National Academy of Sciences

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 520

Histone modification: cause or cog?

Henikoff, S., & Shilatifard, A. (2011) · Trends in Genetics

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 482

Spreading of silent chromatin: inaction at a distance

Talbert, P. B., & Henikoff, S. (2006) · Nature Reviews Genetics

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 300

Position-effect variegation after 60 years

Henikoff, S. (1990) · Trends in Genetics

Genomics and Chromatin DynamicsChromosomal and Genetic Variations

Cited by 280

Single-cell CUT&Tag analysis of chromatin modifications in differentiation and tumor progression

Wu, S. J., Furlan, S. N., Mihalas, A. B., Kaya-Okur, H. S., Feroze, A. H., Emerson, S. N., Zheng, Y., Carson, K., Cimino, P. J., Keene, C. D., et al. (2021) · Nature Biotechnology

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 201

Cell-type-specific nuclei purification from whole animals for genome-wide expression and chromatin profiling

Steiner, F. A., Talbert, P. B., Kasinathan, S., Deal, R. B., & Henikoff, S. (2012) · Genome Research

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 123

Automated in situ chromatin profiling efficiently resolves cell types and gene regulatory programs

Janssens, D. H., Wu, S. J., Sarthy, J. F., Meers, M. P., Myers, C. H., Olson, J. M., Ahmad, K., & Henikoff, S. (2018) · Epigenetics & Chromatin

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 73

Affinity Selection from Biological Libraries

Smothers, J. F., Henikoff, S., & Carter, P. (2002) · Science

Monoclonal and Polyclonal Antibodies ResearchChemical Synthesis and Analysis

Cited by 67

Max deletion destabilizes MYC protein and abrogates Eµ- Myc lymphomagenesis

Mathsyaraja, H., Freie, B., Cheng, P.-F., Babaeva, E., Catchpole, J. T., Janssens, D., Henikoff, S., & Eisenman, R. N. (2019) · Genes & Development

Cancer-related Molecular PathwaysLymphoma Diagnosis and Treatment

Cited by 54