Capra, John A.

DNA Replication through G-Quadruplex Motifs Is Promoted by the Saccharomyces cerevisiae Pif1 DNA Helicase

Paeschke, K., Capra, J. A., & Zakian, V. A. (2011) · Cell

DNA and Nucleic Acid ChemistryDNA Repair Mechanisms

Cited by 566

The phenotypic legacy of admixture between modern humans and Neandertals

Simonti, C. N., Vernot, B., Bastarache, L., Bottinger, E., Carrell, D. S., Chisholm, R. L., Crosslin, D. R., Hebbring, S. J., Jarvik, G. P., Kullo, I. J., et al. (2016) · Science

Pleistocene-Era Hominins and ArchaeologyGenetic Associations and Epidemiology

Cited by 330

SIRT4 is a lysine deacylase that controls leucine metabolism and insulin secretion

Anderson, K. A., Huynh, F. K., Fisher-Wellman, K., Stuart, J. D., Peterson, B. S., Douros, J. D., Wagner, G. R., Thompson, J. W., Madsen, A. S., Green, M. F., et al. (2017) · Cell Metabolism

Sirtuins and Resveratrol in MedicineAutophagy in Disease and Therapy

Cited by 326

The influence of evolutionary history on human health and disease

Benton, M. L., Abraham, A., LaBella, A. L., Abbot, P., Rokas, A., & Capra, J. A. (2021) · Nature Reviews Genetics

Genetic Associations and EpidemiologyEvolution and Genetic Dynamics

Cited by 291

Many human accelerated regions are developmental enhancers

Capra, J. A., Erwin, G. D., McKinsey, G., Rubenstein, J. L. R., & Pollard, K. S. (2013) · Philosophical Transactions of the Royal Society B Biological Sciences

Genomics and Chromatin DynamicsChromosomal and Genetic Variations

Cited by 235

XPA: A key scaffold for human nucleotide excision repair

Sugitani, N., Sivley, R. M., Perry, K. E., Capra, J. A., & Chazin, W. J. (2016) · DNA Repair

DNA Repair MechanismsNuclear Structure and Function

Cited by 116

A model-based analysis of GC-biased gene conversion in the human and chimpanzee genomes

Capra, J. A., Hubisz, M. J., Kostka, D., Pollard, K. S., & Siepel, A. (2013) · PLoS Genetics

Evolution and Genetic DynamicsChromosomal and Genetic Variations

Cited by 77

Quantifying the contribution of Neanderthal introgression to the heritability of complex traits

McArthur, E., Rinker, D. C., & Capra, J. A. (2021) · Nature Communications

Pleistocene-Era Hominins and ArchaeologyGenetic Associations and Epidemiology

Cited by 71

Inferred divergent gene regulation in archaic hominins reveals potential phenotypic differences

Colbran, L. L., Gamazon, E. R., Zhou, D., Evans, P., Cox, N. J., & Capra, J. A. (2019) · Nature Ecology & Evolution

Pleistocene-Era Hominins and ArchaeologyGenetic Associations and Epidemiology

Cited by 50

Neanderthal introgression reintroduced functional ancestral alleles lost in Eurasian populations

Rinker, D. C., Simonti, C. N., McArthur, E., Shaw, D., Hodges, E., & Capra, J. A. (2020) · Nature Ecology & Evolution

Pleistocene-Era Hominins and ArchaeologyGenetic Associations and Epidemiology

Cited by 44

Signatures of Recent Positive Selection in Enhancers Across 41 Human Tissues

Moon, J. M., Capra, J. A., Abbot, P., & Rokas, A. (2019) · G3 Genes|Genomes|Genetics

Evolution and Genetic DynamicsGenetic Associations and Epidemiology

Cited by 24

Archaic Introgression Shaped Human Circadian Traits

Velazquez-Arcelay, K., Colbran, L. L., McArthur, E., Brand, C. M., Rinker, D. C., Siemann, J. K., McMahon, D. G., & Capra, J. A. (2023) · Genome Biology and Evolution

Circadian rhythm and melatoninPleistocene-Era Hominins and Archaeology

Cited by 18

Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning

Estevam, G. O., Linossi, E., Rao, J., Macdonald, C. B., Ravikumar, A., Chrispens, K. M., Capra, J. A., Coyote-Maestas, W., Pimentel, H., Collisson, E. A., et al. (2025) · eLife

Lung Cancer Treatments and MutationsCancer Genomics and Diagnostics

Cited by 17

An active learning framework improves tumor variant interpretation

Blee, A. M., Li, B., Pecen, T., Meiler, J., Nagel, Z. D., Capra, J. A., & Chazin, W. J. (2021) · Cancer Research

Genomics and Rare DiseasesCancer Genomics and Diagnostics

Cited by 7

An Active Learning Framework Improves Tumor Variant Interpretation

Blee, A. M., Li, B., Pecen, T., Meiler, J., Nagel, Z. D., Capra, J. A., & Chazin, W. J. (2022) · Cancer Research

Genomics and Rare DiseasesCancer Genomics and Diagnostics

Cited by 7

Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning

Estevam, G. O., Linossi, E., Rao, J., Macdonald, C. B., Ravikumar, A., Chrispens, K. M., Capra, J. A., Coyote-Maestas, W., Pimentel, H., Collisson, E. A., et al. (2025) · eLife

Lung Cancer Treatments and MutationsCancer Genomics and Diagnostics

Cited by 6

Illuminating the function of the orphan transporter, SLC22A10, in humans and other primates

Yee, S. W., Ferrández-Peral, L., Alentorn-Moron, P., Fontsere, C., Ceylan, M., Koleske, M. L., Handin, N., Artegoitia, V. M., Lara, G., Chien, H.-C., et al. (2024) · Nature Communications

Drug Transport and Resistance MechanismsPharmacogenetics and Drug Metabolism

Cited by 4

Illuminating the Function of the Orphan Transporter, SLC22A10 in Humans and Other Primates

Giacomini, K., Yee, S. W., Ferrández-Peral, L., Alentorn, P., Fontsere, C., Ceylan, M., Koleske, M., Handin, N., Artegoitia, V., Lara, G., et al. (2023) · Research Square

Drug Transport and Resistance MechanismsPharmacogenetics and Drug Metabolism

Cited by 1

Data from An Active Learning Framework Improves Tumor Variant Interpretation

Blee, A. M., Li, B., Pecen, T., Meiler, J., Nagel, Z. D., Capra, J. A., & Chazin, W. J. (2023)

Genomics and Rare DiseasesCancer Genomics and Diagnostics

Cited by 0