Wright, Woodring E.

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

Kim, N. W., Piatyszek, M. A., Prowse, K. R., Harley, C. B., West, M. D., Ho, P. L. C., Coviello, G. M., Wright, W. E., Weinrich, S. L., & Shay, J. W. (1994) · Science

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 7,091

Extension of Life-Span by Introduction of Telomerase into Normal Human Cells

Bodnar, A. G., Ouellette, M., Frolkis, M., Holt, S. E., Chiu, C.-P., Morin, G. B., Harley, C. B., Shay, J. W., Lichtsteiner, S., & Wright, W. E. (1998) · Science

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 4,975

Telomeres and telomerase: three decades of progress

Shay, J. W., & Wright, W. E. (2019) · Nature Reviews Genetics

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 924

Human Telomerase and Its Regulation

Cong, Y.-S., Wright, W. E., & Shay, J. W. (2002) · Microbiology and Molecular Biology Reviews

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 898

Hayflick, his limit, and cellular ageing

Shay, J. W., & Wright, W. E. (2000) · Nature Reviews Molecular Cell Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 764

Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death

Herbert, B.-S., Pitts, A. E., Baker, S. I., Hamilton, S. E., Wright, W. E., Shay, J. W., & Corey, D. R. (1999) · Proceedings of the National Academy of Sciences

Telomeres, Telomerase, and SenescenceDNA and Nucleic Acid Chemistry

Cited by 539

Role of telomeres and telomerase in cancer

Shay, J. W., & Wright, W. E. (2011) · Seminars in Cancer Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 523

Comparative biology of mammalian telomeres: hypotheses on ancestral states and the roles of telomeres in longevity determination

Gomes, N. M. V., Ryder, O. A., Houck, M. L., Charter, S. J., Walker, W., Forsyth, N. R., Austad, S. N., Venditti, C., Pagel, M., Shay, J. W., et al. (2011) · Aging Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 464

Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions

Ramirez, R. D., Morales, C. P., Herbert, B.-S., Rohde, J. M., Passons, C., Shay, J. W., & Wright, W. E. (2001) · Genes & Development

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 444

Telomere dynamics in cancer progression and prevention: fundamental differences in human and mouse telomere biology

Wright, W. E., & Shay, J. W. (2000) · Nature Medicine

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 398

Telomerase, Cell Immortality, and Cancer

Harley, C. B., Kim, N. W., Prowse, K. R., Weinrich, S. L., Hirsch, K. S., West, M. D., Bacchetti, S., Hirte, H. W., Counter, C. M., Greider, C. W., et al. (1994) · Cold Spring Harbor Symposia on Quantitative Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 396

The two-stage mechanism controlling cellular senescence and immortalization

Wright, W. E., & Shay, J. W. (1992) · Experimental Gerontology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 383

Telomerase and differentiation in multicellular organisms: Turn it off, turn it on, and turn it off again

Forsyth, N. R., Wright, W. E., & Shay, J. W. (2002) · Differentiation

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 345

POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end

Hockemeyer, D., Sfeir, A. J., Shay, J. W., Wright, W. E., & de Lange, T. (2005) · The EMBO Journal

Telomeres, Telomerase, and SenescenceDNA and Nucleic Acid Chemistry

Cited by 314

Identification of skeletal muscle precursor cells in vivo by use of MyoD1 and myogenin probes

Grounds, M. D., Garrett, K. L., Lai, M. C., Wright, W. E., & Beilharz, M. W. (1992) · Cell & Tissue Research

Muscle Physiology and DisordersCongenital heart defects research

Cited by 313

Cellular senescence as a tumor-protection mechanism: the essential role of counting

Wright, W. E., & Shay, J. W. (2001) · Current Opinion in Genetics & Development

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 306

Does a Sentinel or a Subset of Short Telomeres Determine Replicative Senescence?

Zou, Y., Sfeir, A., Gryaznov, S. M., Shay, J. W., & Wright, W. E. (2004) · Molecular Biology of the Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 293

In vivo Inhibition of Lung Cancer by GRN163L: A Novel Human Telomerase Inhibitor

Dikmen, Z. G., Gellert, G. C., Jackson, S., Gryaznov, S., Tressler, R., Dogan, P., Wright, W. E., & Shay, J. W. (2005) · Cancer Research

Telomeres, Telomerase, and SenescenceDNA and Nucleic Acid Chemistry

Cited by 271

Telomeropathies: An emerging spectrum disorder

Holohan, B., Wright, W. E., & Shay, J. W. (2014) · Journal of Cell Biology

Telomeres, Telomerase, and SenescenceNuclear Structure and Function

Cited by 175

Telomerase Activity Concentrates in the Mitotically Active Segments of Human Hair Follicles

Ramirez, R. D., Wright, W. E., Shay, J. W., & Taylor, R. S. (1997) · Journal of Investigative Dermatology

Hair Growth and DisordersTelomeres, Telomerase, and Senescence

Cited by 174

The Frequency of Immortalization of Human Fibroblasts and Mammary Epithelial Cells Transfected with SV40 Large T-Antigen

Shay, J. W., van der Haegen, B. A., Ying, Y., & Wright, W. E. (1993) · Experimental Cell Research

Telomeres, Telomerase, and SenescencePolyomavirus and related diseases

Cited by 164

Comparison of the telomeric repeat amplification protocol (TRAP) to the new TRAP-eze telomerase detection kit

Holt, S. E., Norton, J. C., Wright, W. E., & Shay, J. W. (1996) · Methods in Cell Science

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 131

Function of AP-1 in Transcription of the Telomerase Reverse Transcriptase Gene (TERT) in Human and Mouse Cells

Takakura, M., Kyo, S., Inoue, M., Wright, W. E., & Shay, J. W. (2005) · Molecular and Cellular Biology

Telomeres, Telomerase, and SenescenceGenomics and Chromatin Dynamics

Cited by 107

Characterization of ataxia telangiectasia fibroblasts with extended life-span through telomerase expression

Wood, L. D., Halvorsen, T. L., Dhar, S., Baur, J. A., Pandita, R. K., Wright, W. E., Hande, M. P., Calaf, G., Hei, T. K., Levine, F., et al. (2001) · Oncogene

Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms

Cited by 91