Rubin, Eric J.

Genes required for mycobacterial growth defined by high density mutagenesis

Sassetti, C. M., Boyd, D. H., & Rubin, E. J. (2003) · Molecular Microbiology

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 2,544

Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform

Rock, J. M., Hopkins, F. F., Chavez, A., Diallo, M., Chase, M. R., Gerrick, E. R., Pritchard, J. R., Church, G. M., Rubin, E. J., Sassetti, C. M., et al. (2017) · Nature Microbiology

CRISPR and Genetic EngineeringBacterial Genetics and Biotechnology

Cited by 538

Anti-tuberculosis treatment strategies and drug development: challenges and priorities

Dartois, V. A., & Rubin, E. J. (2022) · Nature Reviews Microbiology

Tuberculosis Research and EpidemiologyInfectious Diseases and Tuberculosis

Cited by 490

Bacterial Growth and Cell Division: a Mycobacterial Perspective

Hett, E. C., & Rubin, E. J. (2008) · Microbiology and Molecular Biology Reviews

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 408

Mutually dependent secretion of proteins required for mycobacterial virulence.

Fortune, S. M., Jaeger, A., Sarracino, D. A., Chase, M. R., Sassetti, C. M., Sherman, D. R., Bloom, B. R., & Rubin, E. J. (2005) · Proceedings of the National Academy of Sciences

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 396

The mycobacterial cell envelope — a moving target

Dulberger, C. L., Rubin, E. J., & Boutte, C. C. (2020) · Nature Reviews Microbiology

Tuberculosis Research and EpidemiologyMycobacterium research and diagnosis

Cited by 365

Tryptophan Biosynthesis Protects Mycobacteria from CD4 T-Cell-Mediated Killing

Zhang, Y. J., Reddy, M. C., Ioerger, T. R., Rothchild, A. C., Dartois, V., Schuster, B. M., Trauner, A., Wallis, D., Galaviz, S., Huttenhower, C., et al. (2013) · Cell

Tuberculosis Research and EpidemiologyImmune responses and vaccinations

Cited by 351

Systematic Genetic Nomenclature for Type VII Secretion Systems

Bitter, W., Houben, E. N. G., Bottai, D., Brodin, P., Brown, E. J., Cox, J. S., Derbyshire, K., Fortune, S. M., Gao, L.-Y., Liu, J., et al. (2009) · PLoS Pathogens

Bacterial Genetics and BiotechnologyEscherichia coli research studies

Cited by 307

Artificial Intelligence in Medicine

Beam, A. L., Drazen, J. M., Kohane, I. S., Leong, T.-Y., Manrai, A. K., & Rubin, E. J. (2023) · New England Journal of Medicine

Artificial Intelligence in Healthcare and EducationArtificial Intelligence in Healthcare

Cited by 303

Identification of Host-Targeted Small Molecules That Restrict Intracellular Mycobacterium tuberculosis Growth

Stanley, S. A., Barczak, A. K., Silvis, M. R., Luo, S. S., Sogi, K., Vokes, M., Bray, M.-A., Carpenter, A. E., Moore, C. B., Siddiqi, N., et al. (2014) · PLoS Pathogens

Tuberculosis Research and EpidemiologyInfectious Diseases and Tuberculosis

Cited by 251

Deletion of a mycobacterial divisome factor collapses single-cell phenotypic heterogeneity

Rego, E. H., Audette, R. E., & Rubin, E. J. (2017) · Nature

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 186

Zika Virus and Microcephaly

Rubin, E. J., Greene, M. F., & Baden, L. R. (2016) · New England Journal of Medicine

Mosquito-borne diseases and controlVirology and Viral Diseases

Cited by 150

Identification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus

Laencina, L., Dubois, V., Le Moigne, V., Viljoen, A., Majlessi, L., Pritchard, J., Bernut, A., Piel, L., Roux, A.-L., Gaillard, J.-L., et al. (2018) · Proceedings of the National Academy of Sciences

Mycobacterium research and diagnosisTuberculosis Research and Epidemiology

Cited by 147

Differential Antibiotic Susceptibilities of Starved Mycobacterium tuberculosis Isolates

Xie, Z., Siddiqi, N., & Rubin, E. J. (2005) · Antimicrobial Agents and Chemotherapy

Tuberculosis Research and EpidemiologyMycobacterium research and diagnosis

Cited by 136

Maturing Mycobacterium smegmatis peptidoglycan requires non-canonical crosslinks to maintain shape

Baranowski, C., Welsh, M. A., Sham, L.-T., Eskandarian, H. A., Lim, H. C., Kieser, K. J., Wagner, J. C., McKinney, J. D., Fantner, G. E., Ioerger, T. R., et al. (2018) · eLife

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 132

Feast or famine: the host-pathogen battle over amino acids

Zhang, Y. J., & Rubin, E. J. (2013) · Cellular Microbiology

Bacterial Genetics and BiotechnologyImmune Response and Inflammation

Cited by 117

Mycobacterial Esx-3 Requires Multiple Components for Iron Acquisition

Siegrist, M. S., Steigedal, M., Ahmad, R., Mehra, A., Dragset, M. S., Schuster, B. M., Philips, J. A., Carr, S. A., & Rubin, E. J. (2014) · mBio

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 87

Lipidomic discovery of deoxysiderophores reveals a revised mycobactin biosynthesis pathway in Mycobacterium tuberculosis

Madigan, C. A., Cheng, T.-Y., Layre, E., Young, D. C., McConnell, M. J., Debono, C. A., Murry, J. P., Wei, J.-R., Barry, C. E., Rodriguez, G. M., et al. (2012) · Proceedings of the National Academy of Sciences

Tuberculosis Research and EpidemiologyMicrobial Natural Products and Biosynthesis

Cited by 65

Genome-wide Phenotypic Profiling Identifies and Categorizes Genes Required for Mycobacterial Low Iron Fitness

Dragset, M. S., Ioerger, T. R., Zhang, Y. J., Mærk, M., Ginbot, Z., Sacchettini, J. C., Flo, T. H., Rubin, E. J., & Steigedal, M. (2019) · Scientific Reports

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 49

Transposon mutagenesis in Mycobacterium abscessus identifies an essential penicillin-binding protein involved in septal peptidoglycan synthesis and antibiotic sensitivity

Akusobi, C., Benghomari, B. S., Zhu, J., Wolf, I. D., Singhvi, S., Dulberger, C. L., Ioerger, T. R., & Rubin, E. J. (2022) · eLife

Mycobacterium research and diagnosisBacterial Genetics and Biotechnology

Cited by 45

Spatiotemporal localization of proteins in mycobacteria

Zhu, J., Wolf, I. D., Dulberger, C. L., Won, H. I., Kester, J. C., Judd, J. A., Wirth, S. E., Clark, R. R., Li, Y., Luo, Y., et al. (2021) · Cell Reports

Bacterial Genetics and BiotechnologyCell Image Analysis Techniques

Cited by 32

Reducing the Risks of Nuclear War.

Abbasi, K., Ali, P., Barbour, V., Bibbins-Domingo, K., Olde Rikkert, M. G. M., Haines, A., Helfand, I., Horton, R., Mash, B., Mitra, A., et al. (2023) · Public Health Reviews

Nuclear Issues and DefenseEuropean and Russian Geopolitical Military Strategies

Cited by 2

Ribosomal protection as a linezolid resistance mechanism in Mycobacterium abscessus

Funck, T., McGowen, K., Sullivan, M. R., Zinga, S., Wolf, I. D., Nurjadi, D., Denkinger, C. M., & Rubin, E. J. (2025) · Antimicrobial Agents and Chemotherapy

Mycobacterium research and diagnosisTuberculosis Research and Epidemiology

Cited by 1

Ribosomal protection as a linezolid resistance mechanism in Mycobacterium abscessus

Funck, T., McGowen, K., Sullivan, M. R., Zinga, S., Wolf, I. D., Nurjadi, D., Denkinger, C. M., & Rubin, E. J. (2026) · Antimicrobial Agents and Chemotherapy

Mycobacterium research and diagnosisTuberculosis Research and Epidemiology

Cited by 1