Weller, Roy O.

Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: a case report

Nicoll, J. A. R., Wilkinson, D., Holmes, C., Steart, P., Markham, H., & Weller, R. O. (2003) · Nature Medicine

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 1,397

The movers and shapers in immune privilege of the CNS

Engelhardt, B., Vajkoczy, P., & Weller, R. O. (2017) · Nature Immunology

Barrier Structure and Function StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 893

Cerebral Amyloid Angiopathy

Weller, R. O., Massey, A., Newman, T. A., Hutchings, M., Kuo, Y.-M., & Roher, A. E. (1998) · The American Journal of Pathology

Alzheimer's disease research and treatmentsIntracerebral and Subarachnoid Hemorrhage Research

Cited by 679

Solutes, but not cells, drain from the brain parenchyma along basement membranes of capillaries and arteries: significance for cerebral amyloid angiopathy and neuroimmunology

Carare, R. O., Bernardes‐Silva, M., Newman, T. A., Page, A. M., Nicoll, J. A. R., Perry, V. H., & Weller, R. O. (2008) · Neuropathology and Applied Neurobiology

Cerebrospinal fluid and hydrocephalusBarrier Structure and Function Studies

Cited by 665

CSF drains directly from the subarachnoid space into nasal lymphatics in the rat. Anatomy, histology and immunological significance

Kida, S., Pantazis, A., & Weller, R. O. (1993) · Neuropathology and Applied Neurobiology

Cerebrospinal fluid and hydrocephalusLymphatic System and Diseases

Cited by 520

Lymphatic drainage of the brain and the pathophysiology of neurological disease

Weller, R. O., Djuanda, E., Yow, H.-Y., & Carare, R. O. (2009) · Acta Neuropathologica

Cerebrospinal fluid and hydrocephalusLymphatic System and Diseases

Cited by 488

Vascular, glial, and lymphatic immune gateways of the central nervous system

Engelhardt, B., Carare, R. O., Bechmann, I., Flügel, A., Laman, J. D., & Weller, R. O. (2016) · Acta Neuropathologica

Barrier Structure and Function StudiesCerebrospinal fluid and hydrocephalus

Cited by 362

Lymphatic Clearance of the Brain: Perivascular, Paravascular and Significance for Neurodegenerative Diseases

Bakker, E. N. T. P., Bacskai, B. J., Arbel-Ornath, M., Aldea, R., Bedussi, B., Morris, A. W. J., Weller, R. O., & Carare, R. O. (2016) · Cellular and Molecular Neurobiology

Cerebrospinal fluid and hydrocephalusBarrier Structure and Function Studies

Cited by 353

Convective influx/glymphatic system: tracers injected into the CSF enter and leave the brain along separate periarterial basement membrane pathways

Albargothy, N. J., Johnston, D. A., MacGregor-Sharp, M., Weller, R. O., Verma, A., Hawkes, C. A., & Carare, R. O. (2018) · Acta Neuropathologica

Cerebrospinal fluid and hydrocephalusBarrier Structure and Function Studies

Cited by 311

Microvasculature changes and cerebral amyloid angiopathy in Alzheimer’s disease and their potential impact on therapy

Weller, R. O., Boche, D., & Nicoll, J. A. R. (2009) · Acta Neuropathologica

Alzheimer's disease research and treatmentsCerebrospinal fluid and hydrocephalus

Cited by 297

Mechanisms to explain the reverse perivascular transport of solutes out of the brain

Schley, D., Carare-Nnadi, R., Please, C. P., Perry, V. H., & Weller, R. O. (2006) · Journal of Theoretical Biology

Cerebrospinal fluid and hydrocephalusBarrier Structure and Function Studies

Cited by 293

Vascular basement membranes as pathways for the passage of fluid into and out of the brain

Morris, A. W. J., Sharp, M. M., Albargothy, N. J., Fernandes, R., Hawkes, C. A., Verma, A., Weller, R. O., & Carare, R. O. (2016) · Acta Neuropathologica

Cerebrospinal fluid and hydrocephalusBarrier Structure and Function Studies

Cited by 289

Anatomical relationships of the pia mater to cerebral blood vessels in man

Hutchings, M., & Weller, R. O. (1986) · Journal of Neurosurgery

Cerebrospinal fluid and hydrocephalusBarrier Structure and Function Studies

Cited by 233

Pathology of Cerebrospinal Fluid and Interstitial Fluid of the CNS: Significance for Alzheimer Disease, Prion Disorders and Multiple Sclerosis

Weller, R. O. (1998) · Journal of Neuropathology and Experimental Neurology

Cerebrospinal fluid and hydrocephalusAlzheimer's disease research and treatments

Cited by 224

The meninges as barriers and facilitators for the movement of fluid, cells and pathogens related to the rodent and human CNS.

Weller, R. O., Sharp, M. M., Christodoulides, M., Carare, R. O., & Møllgård, K. (2018) · Acta Neuropathologica

Cerebrospinal fluid and hydrocephalusBarrier Structure and Function Studies

Cited by 222

Perivascular spaces in the basal ganglia of the human brain: their relationship to lacunes

POLLOCK, H., HUTCHINGS, M., WELLER, R. O., & ZHANG, E. (1997) · Journal of Anatomy

Cerebrospinal fluid and hydrocephalusBarrier Structure and Function Studies

Cited by 220

Review: Cerebral amyloid angiopathy, prion angiopathy, CADASIL and the spectrum of protein elimination failure angiopathies (PEFA) in neurodegenerative disease with a focus on therapy

Carare, R. O., Hawkes, C. A., Jeffrey, M., Kalaria, R. N., & Weller, R. O. (2013) · Neuropathology and Applied Neurobiology

Barrier Structure and Function StudiesIntracerebral and Subarachnoid Hemorrhage Research

Cited by 207

Perivascular cells act as scavengers in the cerebral perivascular spaces and remain distinct from pericytes, microglia and macrophages

Kida, S., Steart, P. V., Zhang, E.-T., & Weller, R. O. (1993) · Acta Neuropathologica

Cerebrospinal fluid and hydrocephalusNeuroinflammation and Neurodegeneration Mechanisms

Cited by 189

The Evolution of Aβ Peptide Burden in the APP23 Transgenic Mice: Implications for Aβ Deposition in Alzheimer Disease

Kuo, Y.-M., Beach, T. G., Sue, L. I., Scott, S., Layne, K. J., Kokjohn, T. A., Kalback, W. M., Luehrs, D. C., Vishnivetskaya, T. A., Abramowski, D., et al. (2001) · Molecular Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 90

Interactions of Neisseria meningitidis with cells of the human meninges

Hardy, S. J., Christodoulides, M., Weller, R. O., & Heckels, J. E. (2000) · Molecular Microbiology

Bacterial Infections and VaccinesEscherichia coli research studies

Cited by 78

A new role for astrocytes: β-amyloid homeostasis and degradation

Nicoll, J. A. R., & Weller, R. O. (2003) · Trends in Molecular Medicine

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 51

The perivascular pathways for influx of cerebrospinal fluid are most efficient in the midbrain

Dobson, H., Sharp, M. M., Cumpsty, R., Criswell, T. P., Wellman, T., Finucane, C., Sullivan, J. M., Weller, R. O., Verma, A., & Carare, R. O. (2017) · Clinical Science

Cerebrospinal fluid and hydrocephalusBarrier Structure and Function Studies

Cited by 27

ApoE4 Astrocytes Secrete Basement Membranes Rich in Fibronectin and Poor in Laminin Compared to ApoE3 Astrocytes

Keable, A., O’Neill, R., MacGregor Sharp, M., Gatherer, M., Yuen, H. M., Johnston, D. A., Weller, R. O., & Carare, R. O. (2020) · International Journal of Molecular Sciences

Alzheimer's disease research and treatmentsBarrier Structure and Function Studies

Cited by 15