Breslow, Jan L.

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

Plump, A. S., Smith, J. D., Hayek, T., Aalto-Setälä, K., Walsh, A., Verstuyft, J. G., Rubin, E. M., & Breslow, J. L. (1992) · Cell

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 2,263

ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree.

Nakashima, Y., Plump, A. S., Raines, E. W., Breslow, J. L., & Ross, R. (1994) · Arteriosclerosis and Thrombosis: A Journal of Vascular Biology

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 1,693

Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance

Kim, J. K., Fillmore, J. J., Chen, Y., Yu, C., Moore, I. K., Pypaert, M., Lutz, E. P., Kako, Y., Velez-Carrasco, W., Goldberg, I. J., et al. (2001) · Proceedings of the National Academy of Sciences

Lipid metabolism and disordersMetabolism, Diabetes, and Cancer

Cited by 753

Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotype

Maxwell, K. N., & Breslow, J. L. (2004) · Proceedings of the National Academy of Sciences

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 613

Human very low density lipoprotein apolipoprotein E isoprotein polymorphism is explained by genetic variation and posttranslational modification

Zannis, V. I., & Breslow, J. L. (1981) · Biochemistry

Lipoproteins and Cardiovascular HealthLipid metabolism and disorders

Cited by 563

Hypertriglyceridemia as a Result of Human apo CII Gene Expression in Transgenic Mice

Ito, Y., Azrolan, N., O'Connell, A., Walsh, A., & Breslow, J. L. (1990) · Science

Lipid metabolism and disordersCholesterol and Lipid Metabolism

Cited by 539

Whole population, genome-wide mapping of hidden relatedness

Gusev, A., Lowe, J. K., Stoffel, M., Daly, M. J., Altshuler, D., Breslow, J. L., Friedman, J. M., & Pe'er, I. (2009) · Genome Research

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 450

Proposed nomenclature of apoE isoproteins, apoE genotypes, and phenotypes

Zannis, V. I., Breslow, J. L., Utermann, G., Mahley, R. W., Weisgraber, K. H., Havel, R. J., Goldstein, J. L., Brown, M. S., Schonfeld, G., Hazzard, W. R., et al. (1982) · Journal of Lipid Research

Lipoproteins and Cardiovascular HealthAlzheimer's disease research and treatments

Cited by 436

Overexpression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment

Maxwell, K. N., Fisher, E. A., & Breslow, J. L. (2005) · Proceedings of the National Academy of Sciences

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 415

Dietary polyunsaturated fats of the W-6 and W-3 series reduce postprandial lipoprotein levels. Chronic and acute effects of fat saturation on postprandial lipoprotein metabolism.

Weintraub, M. S., Zechner, R., Brown, A., Eisenberg, S., & Breslow, J. L. (1988) · Journal of Clinical Investigation

Fatty Acid Research and HealthLipid metabolism and disorders

Cited by 331

StAR-related lipid transfer (START) proteins: mediators of intracellular lipid metabolism

Soccio, R. E., & Breslow, J. L. (2003) · Journal of Biological Chemistry

Lipid metabolism and biosynthesisCholesterol and Lipid Metabolism

Cited by 308

Intracellular cholesterol transport

Soccio, R. E., & Breslow, J. L. (2004) · Arteriosclerosis, Thrombosis, and Vascular Biology

Cholesterol and Lipid MetabolismCancer, Lipids, and Metabolism

Cited by 297

Common genetic variation in the promoter of the human apo CIII gene abolishes regulation by insulin and may contribute to hypertriglyceridemia.

Li, W. W., Dammerman, M. M., Smith, J. D., Metzger, S., Breslow, J. L., & Leff, T. (1995) · Journal of Clinical Investigation

Lipid metabolism and disordersGenetic Associations and Epidemiology

Cited by 278

Human HDL cholesterol levels are determined by apoA-I fractional catabolic rate, which correlates inversely with estimates of HDL particle size. Effects of gender, hepatic and lipoprotein lipases, triglyceride and insulin levels, and body fat distribution.

Brinton, E. A., Eisenberg, S., & Breslow, J. L. (1994) · Arteriosclerosis and Thrombosis: A Journal of Vascular Biology

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 265

Different patterns of postprandial lipoprotein metabolism in normal, type IIa, type III, and type IV hyperlipoproteinemic individuals. Effects of treatment with cholestyramine and gemfibrozil.

Weintraub, M. S., Eisenberg, S., & Breslow, J. L. (1987) · Journal of Clinical Investigation

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 261

How do we improve patient compliance and adherence to long-term statin therapy?

Maningat, P., Gordon, B. R., & Breslow, J. L. (2013) · Current Atherosclerosis Reports

Medication Adherence and ComplianceLipoproteins and Cardiovascular Health

Cited by 208

Scavenger Receptor BI (SR-BI) Is Up-regulated in Adrenal Gland in Apolipoprotein A-I and Hepatic Lipase Knock-out Mice as a Response to Depletion of Cholesterol Stores

Wang, N., Wang, W., Breslow, J. L., & Tall, A. R. (1996) · Journal of Biological Chemistry

Cholesterol and Lipid MetabolismLipid metabolism and disorders

Cited by 205

The cholesterol-regulated StarD4 gene encodes a StAR-related lipid transfer protein with two closely related homologues, StarD5 and StarD6

Soccio, R. E., Adams, R. M., Romanowski, M. J., Sehayek, E., Burley, S. K., & Breslow, J. L. (2002) · Proceedings of the National Academy of Sciences

Cholesterol and Lipid MetabolismLipid metabolism and biosynthesis

Cited by 188

Studies of familial type III hyperlipoproteinemia using as a genetic marker the apoE phenotype E2/2

Breslow, J. L., Zannis, V. I., SanGiacomo, T. R., Third, J. L., Tracy, T., & Glueck, C. J. (1982) · Journal of Lipid Research

Lipoproteins and Cardiovascular HealthLipid metabolism and disorders

Cited by 174

Crystal structure of the Mus musculus cholesterol-regulated START protein 4 (StarD4) containing a StAR-related lipid transfer domain

Romanowski, M. J., Soccio, R. E., Breslow, J. L., & Burley, S. K. (2002) · Proceedings of the National Academy of Sciences

Cholesterol and Lipid MetabolismProtein Structure and Dynamics

Cited by 162

Intestinal absorption of dietary cholesteryl ester is decreased but retinyl ester absorption is normal in carboxyl ester lipase knockout mice

Weng, W., Li, L., van Bennekum, A. M., Potter, S. H., Harrison, E. H., Blaner, W. S., Breslow, J. L., & Fisher, E. A. (1999) · Biochemistry

Lipid metabolism and disordersCholesterol and Lipid Metabolism

Cited by 135

Algal Docosahexaenoic Acid Affects Plasma Lipoprotein Particle Size Distribution in Overweight and Obese Adults

Neff, L. M., Culiner, J., Cunningham-Rundles, S., Seidman, C., Meehan, D., Maturi, J., Wittkowski, K. M., Levine, B., & Breslow, J. L. (2011) · The Journal of Nutrition

Fatty Acid Research and HealthLipoproteins and Cardiovascular Health

Cited by 121

Differential gene regulation of StarD4 and StarD5 cholesterol transfer proteins

Soccio, R. E., Adams, R. M., Maxwell, K. N., & Breslow, J. L. (2005) · Journal of Biological Chemistry

Cholesterol and Lipid MetabolismCancer, Lipids, and Metabolism

Cited by 118

Proprotein convertase subtilisin kexin 9: The third locus implicated in autosomal dominant hypercholesterolemia

Maxwell, K. N., & Breslow, J. L. (2005) · Current Opinion in Lipidology

Lipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

Cited by 82