Briscoe, James

The mechanisms of Hedgehog signalling and its roles in development and disease

Briscoe, J., & Thérond, P. P. (2013) · Nature Reviews Molecular Cell Biology

Hedgehog Signaling Pathway StudiesGenetic and Kidney Cyst Diseases

Cited by 1,751

Neural crest development is regulated by the transcription factor Sox9

Cheung, M., & Briscoe, J. (2003) · Development

Developmental Biology and Gene RegulationNeurogenesis and neuroplasticity mechanisms

Cited by 482

The transcriptional control of trunk neural crest induction, survival, and delamination

Cheung, M., Chaboissier, M.-C., Mynett, A., Hirst, E., Schedl, A., & Briscoe, J. (2005) · Developmental Cell

Developmental Biology and Gene RegulationNeurogenesis and neuroplasticity mechanisms

Cited by 427

Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon‐alpha and ‐gamma signal transduction pathways.

Müller, M., Laxton, C., Briscoe, J., Schindler, C., Improta, T., Darnell, J. E., Stark, G. R., & Kerr, I. M. (1993) · The EMBO Journal

interferon and immune responsesCytokine Signaling Pathways and Interactions

Cited by 411

Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord

Delile, J., Rayon, T., Melchionda, M., Edwards, A., Briscoe, J., & Sagner, A. (2019) · Development

Single-cell and spatial transcriptomicsDevelopmental Biology and Gene Regulation

Cited by 356

Establishing and Interpreting Graded Sonic Hedgehog Signaling during Vertebrate Neural Tube Patterning: The Role of Negative Feedback

Ribes, V., & Briscoe, J. (2009) · Cold Spring Harbor Perspectives in Biology

Hedgehog Signaling Pathway StudiesDevelopmental Biology and Gene Regulation

Cited by 232

Sonic Hedgehog Dependent Phosphorylation by CK1α and GRK2 Is Required for Ciliary Accumulation and Activation of Smoothened

Chen, Y., Sasai, N., Ma, G., Yue, T., Jia, J., Briscoe, J., & Jiang, J. (2011) · PLoS Biology

Hedgehog Signaling Pathway StudiesGenetic and Kidney Cyst Diseases

Cited by 225

Dynamic Assignment and Maintenance of Positional Identity in the Ventral Neural Tube by the Morphogen Sonic Hedgehog

Dessaud, E., Ribes, V., Balaskas, N., Yang, L. L., Pierani, A., Kicheva, A., Novitch, B. G., Briscoe, J., & Sasai, N. (2010) · PLoS Biology

Hedgehog Signaling Pathway StudiesDevelopmental Biology and Gene Regulation

Cited by 203

Coordination of progenitor specification and growth in mouse and chick spinal cord

Kicheva, A., Bollenbach, T., Ribeiro, A., Valle, H. P., Lovell-Badge, R., Episkopou, V., & Briscoe, J. (2014) · Science

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 180

Development-on-chip: in vitro neural tube patterning with a microfluidic device

Demers, C. J., Soundararajan, P., Chennampally, P., Cox, G. A., Briscoe, J., Collins, S. D., & Smith, R. L. (2016) · Development

Developmental Biology and Gene RegulationMicrofluidic and Capillary Electrophoresis Applications

Cited by 149

Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics

Sagner, A., Gaber, Z. B., Delile, J., Kong, J. H., Rousso, D. L., Pearson, C. A., Weicksel, S. E., Melchionda, M., Mousavy Gharavy, S. N., Briscoe, J., et al. (2018) · PLoS Biology

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 96

G protein–coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog

Pusapati, G. V., Kong, J. H., Patel, B. B., Gouti, M., Sagner, A., Sircar, R., Luchetti, G., Ingham, P. W., Briscoe, J., & Rohatgi, R. (2018) · Science Signaling

Hedgehog Signaling Pathway StudiesReceptor Mechanisms and Signaling

Cited by 91

Neural progenitors adopt specific identities by directly repressing all alternative progenitor transcriptional programs

Kutejova, E., Sasai, N., Shah, A., Gouti, M., & Briscoe, J. (2016) · Developmental Cell

Developmental Biology and Gene RegulationNeurogenesis and neuroplasticity mechanisms

Cited by 87

Optimal control of gene regulatory networks for morphogen-driven tissue patterning

Pezzotta, A., & Briscoe, J. (2023) · Cell Systems

Gene Regulatory Network AnalysisDevelopmental Biology and Gene Regulation

Cited by 34