Prinz, Marco

Analyzing microglial phenotypes across neuropathologies: a practical guide

Schwabenland, M., Brück, W., Priller, J., Stadelmann, C., Lassmann, H., & Prinz, M. (2021) · Acta Neuropathologica

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 149

Type I Interferon Receptor Signaling of Neurons and Astrocytes Regulates Microglia Activation during Viral Encephalitis

Chhatbar, C., Detje, C. N., Grabski, E., Borst, K., Spanier, J., Ghita, L., Elliott, D. A., Jordão, M. J. C., Mueller, N., Sutton, J., et al. (2018) · Cell Reports

Neuroinflammation and Neurodegeneration Mechanismsinterferon and immune responses

Cited by 141

Microglia: unique and common features with other tissue macrophages

Prinz, M., Tay, T. L., Wolf, Y., & Jung, S. (2014) · Acta Neuropathologica

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 126

Different effects of constitutive and induced microbiota modulation on microglia in a mouse model of Alzheimer’s disease

Mezö, C., Dokalis, N., Mossad, O., Staszewski, O., Neuber, J., Yilmaz, B., Schnepf, D., de Agüero, M. G., Ganal-Vonarburg, S. C., Macpherson, A. J., et al. (2020) · Acta Neuropathologica Communications

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 120

IκB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-κB in the central nervous system

Raasch, J., Zeller, N., van Loo, G., Merkler, D., Mildner, A., Erny, D., Knobeloch, K.-P., Bethea, J. R., Waisman, A., Knust, M., et al. (2011) · Brain

Multiple Sclerosis Research StudiesNF-κB Signaling Pathways

Cited by 106

CD 14 is a key organizer of microglial responses to CNS infection and injury

Janova, H., Böttcher, C., Holtman, I. R., Regen, T., van Rossum, D., Götz, A., Ernst, A., Fritsche, C., Gertig, U., Saiepour, N., et al. (2016) · Glia

Neuroinflammation and Neurodegeneration MechanismsImmune Response and Inflammation

Cited by 105

A comparative analysis of microglial inducible Cre lines

Faust, T. E., Feinberg, P. A., O’Connor, C., Kawaguchi, R., Chan, A., Strasburger, H., Frosch, M., Boyle, M. A., Masuda, T., Amann, L., et al. (2023) · Cell Reports

Neuroinflammation and Neurodegeneration MechanismsCRISPR and Genetic Engineering

Cited by 103

Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease

Schäffner, E., Bosch-Queralt, M., Edgar, J. M., Lehning, M., Strauß, J., Fleischer, N., Kungl, T., Wieghofer, P., Berghoff, S. A., Reinert, T., et al. (2023) · Nature Neuroscience

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 101

Microglia metabolism in health and disease

Borst, K., Schwabenland, M., & Prinz, M. (2019) · Neurochemistry International

Neuroinflammation and Neurodegeneration MechanismsImmune cells in cancer

Cited by 95

Diet-dependent regulation of TGFβ impairs reparative innate immune responses after demyelination

Bosch-Queralt, M., Cantuti-Castelvetri, L., Damkou, A., Schifferer, M., Schlepckow, K., Alexopoulos, I., Lütjohann, D., Klose, C., Vaculčiaková, L., Masuda, T., et al. (2021) · Nature Metabolism

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 88

Prion pathogenesis in the absence of Toll-like receptor signalling

Prinz, M., Heikenwalder, M., Schwarz, P., Takeda, K., Akira, S., & Aguzzi, A. (2003) · The EMBO Reports

Prion Diseases and Protein MisfoldingNeuroinflammation and Neurodegeneration Mechanisms

Cited by 85

Truncated Prion Protein and Doppel Are Myelinotoxic in the Absence of Oligodendrocytic PrPC

Radovanovic, I., Braun, N., Giger, O. T., Mertz, K., Miele, G., Prinz, M., Navarro, B., & Aguzzi, A. (2005) · The Journal of Neuroscience

Prion Diseases and Protein MisfoldingAlzheimer's disease research and treatments

Cited by 82

Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology

Aguado, J., Amarilla, A. A., Taherian Fard, A., Albornoz, E. A., Tyshkovskiy, A., Schwabenland, M., Chaggar, H. K., Modhiran, N., Gómez-Inclán, C., Javed, I., et al. (2023) · Nature Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 80

Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology

Aguado, J., Amarilla, A. A., Taherian Fard, A., Albornoz, E. A., Tyshkovskiy, A., Schwabenland, M., Chaggar, H. K., Modhiran, N., Gómez-Inclán, C., Javed, I., et al. (2023) · Nature Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 80

Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology

Aguado, J., Amarilla, A., Fard, A. T., Albornoz, E., Tyshkovskiy, A., Schwabenland, M., Chaggar, H., Modhiran, N., Gómez-Inclán, C., Javed, I., et al. (2023) · Nature Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 80

Comparative analysis of CreER transgenic mice for the study of brain macrophages: A case study

Chappell‐Maor, L., Kolesnikov, M., Kim, J., Shemer, A., Haimon, Z., Grozovski, J., Boura‐Halfon, S., Masuda, T., Prinz, M., & Jung, S. (2020) · European Journal of Immunology

Neuroinflammation and Neurodegeneration MechanismsAnimal Genetics and Reproduction

Cited by 70

Paracaspase MALT1 deficiency protects mice from autoimmune-mediated demyelination

Mc Guire, C., Wieghofer, P., Elton, L., Muylaert, D., Prinz, M., Beyaert, R., & van Loo, G. (2013) · The Journal of Immunology

Multiple Sclerosis Research StudiesNF-κB Signaling Pathways

Cited by 67

A pain-mediated neural signal induces relapse in murine autoimmune encephalomyelitis, a multiple sclerosis model

Arima, Y., Kamimura, D., Atsumi, T., Harada, M., Kawamoto, T., Nishikawa, N., Stofkova, A., Ohki, T., Higuchi, K., Morimoto, Y., et al. (2015) · eLife

Multiple Sclerosis Research StudiesPain Mechanisms and Treatments

Cited by 66

The niche matters: Origin, function and fate of CNS-associated macrophages during health and disease

Dalmau Gasull, A., Glavan, M., Samawar, S. K. R., Kapupara, K., Kelk, J., Rubio, M., Fumagalli, S., Sorokin, L., Vivien, D., & Prinz, M. (2024) · Acta Neuropathologica

Neuroinflammation and Neurodegeneration MechanismsBarrier Structure and Function Studies

Cited by 60

GPCRomics of homeostatic and disease-associated human microglia

Hsiao, C.-C., Sankowski, R., Prinz, M., Smolders, J., Huitinga, I., & Hamann, J. (2021) · Frontiers in Immunology

Neuroinflammation and Neurodegeneration MechanismsReceptor Mechanisms and Signaling

Cited by 59

Safeguard function of PU.1 shapes the inflammatory epigenome of neutrophils

Fischer, J., Walter, C., Tönges, A., Aleth, H., Jordão, M. J. C., Leddin, M., Gröning, V., Erdmann, T., Lenz, G., Roth, J., et al. (2019) · Nature Immunology

Neutrophil, Myeloperoxidase and Oxidative MechanismsGenomics and Chromatin Dynamics

Cited by 56

Mechanisms of myeloid cell entry to the healthy and diseased central nervous system

Amann, L., Masuda, T., & Prinz, M. (2023) · Nature Immunology

Neuroinflammation and Neurodegeneration MechanismsBarrier Structure and Function Studies

Cited by 50

Regulation of microglial physiology by the microbiota

Cook, J., & Prinz, M. (2022) · Gut Microbes

Gut microbiota and healthNeuroinflammation and Neurodegeneration Mechanisms

Cited by 49

Infiltration of circulating myeloid cells through CD95L contributes to neurodegeneration in mice

Gao, L., Brenner, D., Llorens-Bobadilla, E., Saiz-Castro, G., Frank, T., Wieghofer, P., Hill, O., Thiemann, M., Karray, S., Prinz, M., et al. (2015) · Journal of Experimental Medicine

Neuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and Treatments

Cited by 42