Prinz, Marco

The enteric nervous system relays psychological stress to intestinal inflammation

Schneider, K. M., Blank, N., Alvarez, Y., Thum, K., Lundgren, P., Litichevskiy, L., Sleeman, M., Bahnsen, K., Kim, J., Kardo, S., et al. (2023) · Cell

Inflammatory Bowel DiseaseGastrointestinal motility and disorders

Cited by 344

Single-cell mass cytometry reveals distinct populations of brain myeloid cells in mouse neuroinflammation and neurodegeneration models

Ajami, B., Samusik, N., Wieghofer, P., Ho, P. P., Crotti, A., Bjornson, Z., Prinz, M., Fantl, W. J., Nolan, G. P., & Steinman, L. (2018) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 338

Novel Hexb-based tools for studying microglia in the CNS

Masuda, T., Amann, L., Sankowski, R., Staszewski, O., Lenz, M., d´Errico, P., Snaidero, N., Costa Jordão, M. J., Böttcher, C., Kierdorf, K., et al. (2020) · Nature Immunology

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 317

Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis

Berghoff, S. A., Spieth, L., Sun, T., Hosang, L., Schlaphoff, L., Depp, C., Düking, T., Winchenbach, J., Neuber, J., Ewers, D., et al. (2021) · Nature Neuroscience

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 307

Specification of CNS macrophage subsets occurs postnatally in defined niches

Masuda, T., Amann, L., Monaco, G., Sankowski, R., Staszewski, O., Krueger, M., Del Gaudio, F., He, L., Paterson, N., Nent, E., et al. (2022) · Nature

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 294

Barcoded viral tracing of single-cell interactions in central nervous system inflammation

Clark, I. C., Gutiérrez-Vázquez, C., Wheeler, M. A., Li, Z., Rothhammer, V., Linnerbauer, M., Sanmarco, L. M., Guo, L., Blain, M., Zandee, S. E. J., et al. (2021) · Science

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 285

Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner

Deczkowska, A., Matcovitch-Natan, O., Tsitsou-Kampeli, A., Ben-Hamo, S., Dvir-Szternfeld, R., Spinrad, A., Singer, O., David, E., Winter, D. R., Smith, L. K., et al. (2017) · Nature Communications

Neuroinflammation and Neurodegeneration Mechanismsinterferon and immune responses

Cited by 260

Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N6-carboxymethyllysine

Mossad, O., Batut, B., Yilmaz, B., Dokalis, N., Mezö, C., Nent, E., Nabavi, L. S., Mayer, M., Maron, F. J. M., Buescher, J. M., et al. (2022) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsGut microbiota and health

Cited by 241

A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation

Voet, S., Mc Guire, C., Hagemeyer, N., Martens, A., Schroeder, A., Wieghofer, P., Daems, C., Staszewski, O., Vande Walle, L., Jordao, M. J. C., et al. (2018) · Nature Communications

Neuroinflammation and Neurodegeneration MechanismsInflammasome and immune disorders

Cited by 227

The neurovascular unit as a selective barrier to polymorphonuclear granulocyte (PMN) infiltration into the brain after ischemic injury

Enzmann, G., Mysiorek, C., Gorina, R., Cheng, Y.-J., Ghavampour, S., Hannocks, M.-J., Prinz, V., Dirnagl, U., Endres, M., Prinz, M., et al. (2013) · Acta Neuropathologica

Barrier Structure and Function StudiesAcute Ischemic Stroke Management

Cited by 225

USP18 lack in microglia causes destructive interferonopathy of the mouse brain

Goldmann, T., Zeller, N., Raasch, J., Kierdorf, K., Frenzel, K., Ketscher, L., Basters, A., Staszewski, O., Brendecke, S. M., Spiess, A., et al. (2015) · The EMBO Journal

Neuroinflammation and Neurodegeneration Mechanismsinterferon and immune responses

Cited by 223

Microglia contribute to the propagation of Aβ into unaffected brain tissue

d’Errico, P., Ziegler-Waldkirch, S., Aires, V., Hoffmann, P., Mezö, C., Erny, D., Monasor, L. S., Liebscher, S., Ravi, V. M., Joseph, K., et al. (2022) · Nature Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 214

Lack of Neuronal IFN-β-IFNAR Causes Lewy Body- and Parkinson’s Disease-like Dementia

Ejlerskov, P., Hultberg, J. G., Wang, J., Carlsson, R., Ambjørn, M., Kuss, M., Liu, Y., Porcu, G., Kolkova, K., Friis Rundsten, C., et al. (2015) · Cell

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 211

A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease

Mass, E., Jacome-Galarza, C. E., Blank, T., Lazarov, T., Durham, B. H., Ozkaya, N., Pastore, A., Schwabenland, M., Chung, Y. R., Rosenblum, M. K., et al. (2017) · Nature

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 210

Essential Role of Ubiquitin-Specific Protease 8 for Receptor Tyrosine Kinase Stability and Endocytic Trafficking In Vivo

Niendorf, S., Oksche, A., Kisser, A., Löhler, J., Prinz, M., Schorle, H., Feller, S., Lewitzky, M., Horak, I., & Knobeloch, K.-P. (2007) · Molecular and Cellular Biology

Ubiquitin and proteasome pathwaysCellular transport and secretion

Cited by 207

Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner

Datta, M., Staszewski, O., Raschi, E., Frosch, M., Hagemeyer, N., Tay, T. L., Blank, T., Kreutzfeldt, M., Merkler, D., Ziegler-Waldkirch, S., et al. (2018) · Immunity

Neuroinflammation and Neurodegeneration MechanismsHistone Deacetylase Inhibitors Research

Cited by 206

Dendritic Cells Ameliorate Autoimmunity in the CNS by Controlling the Homeostasis of PD-1 Receptor+ Regulatory T Cells

Yogev, N., Frommer, F., Lukas, D., Kautz-Neu, K., Karram, K., Ielo, D., von Stebut, E., Probst, H.-C., van den Broek, M., Riethmacher, D., et al. (2012) · Immunity

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 197

Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping

Di Liberto, G., Pantelyushin, S., Kreutzfeldt, M., Page, N., Musardo, S., Coras, R., Steinbach, K., Vincenti, I., Klimek, B., Lingner, T., et al. (2018) · Cell

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 195

Tickets to the brain: Role of CCR2 and CX3CR1 in myeloid cell entry in the CNS

Prinz, M., & Priller, J. (2010) · Journal of Neuroimmunology

Chemokine receptors and signalingNeuroinflammation and Neurodegeneration Mechanisms

Cited by 172

Microglia plasticity during health and disease: An immunological perspective

Shemer, A., Erny, D., Jung, S., & Prinz, M. (2015) · Trends in Immunology

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 168

Hypothalamic innate immune reaction in obesity

Kälin, S., Heppner, F. L., Bechmann, I., Prinz, M., Tschöp, M. H., & Yi, C.-X. (2015) · Nature Reviews Endocrinology

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 167

Dynamics of monocyte-derived macrophage diversity in experimental myocardial infarction

Rizzo, G., Gropper, J., Piollet, M., Vafadarnejad, E., Rizakou, A., Bandi, S. R., Arampatzi, P., Krammer, T., DiFabion, N., Dietrich, O., et al. (2023) · Cardiovascular Research

Cardiac Fibrosis and RemodelingAtherosclerosis and Cardiovascular Diseases

Cited by 165

Multiomic spatial landscape of innate immune cells at human central nervous system borders

Sankowski, R., Süß, P., Benkendorff, A., Böttcher, C., Fernandez-Zapata, C., Chhatbar, C., Cahueau, J., Monaco, G., Gasull, A. D., Khavaran, A., et al. (2024) · Nature Medicine

Single-cell and spatial transcriptomicsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 156

Mononuclear phagocytes locally specify and adapt their phenotype in a multiple sclerosis model

Locatelli, G., Theodorou, D., Kendirli, A., Jordão, M. J. C., Staszewski, O., Phulphagar, K., Cantuti-Castelvetri, L., Dagkalis, A., Bessis, A., Simons, M., et al. (2018) · Nature Neuroscience

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 155