Rhee, Sue Goo

H 2 O 2 , a Necessary Evil for Cell Signaling

Rhee, S. G. (2006) · Science

Redox biology and oxidative stressNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 2,160

Regulation of Phosphoinositide-Specific Phospholipase C

Rhee, S. G. (2001) · Annual Review of Biochemistry

Protein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR signaling in cancer

Cited by 1,628

Peroxiredoxins: A historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling

Rhee, S. G., Chae, H. Z., & Kim, K. (2005) · Free Radical Biology and Medicine

Redox biology and oxidative stressSelenium in Biological Systems

Cited by 1,409

Reversible inactivation of protein-tyrosine phosphatase 1B in A431 cells stimulated with epidermal growth factor

Lee, S.-R., Kwon, K.-S., Kim, S.-R., & Rhee, S. G. (1998) · Journal of Biological Chemistry

Protein Tyrosine PhosphatasesRedox biology and oxidative stress

Cited by 969

Regulation of Phosphoinositide-specific Phospholipase C Isozymes

Rhee, S. G., & Bae, Y. S. (1997) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR signaling in cancer

Cited by 876

Unraveling the biological roles of reactive oxygen species

Murphy, M. P., Holmgren, A., Larsson, N.-G., Halliwell, B., Chang, C. J., Kalyanaraman, B., Rhee, S. G., Thornalley, P. J., Partridge, L., Gems, D., et al. (2011) · Cell Metabolism

Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress

Cited by 836

Redox-based regulation of signal transduction: principles, pitfalls, and promises

Janssen-Heininger, Y. M. W., Mossman, B. T., Heintz, N. H., Forman, H. J., Kalyanaraman, B., Finkel, T., Stamler, J. S., Rhee, S. G., & van der Vliet, A. (2008) · Free Radical Biology and Medicine

Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress

Cited by 784

Redox signaling: hydrogen peroxide as intracellular messenger

Rhee, S. G. (1999) · Experimental & Molecular Medicine

Redox biology and oxidative stressNitric Oxide and Endothelin Effects

Cited by 701

Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors

Kwon, J., Lee, S.-R., Yang, K.-S., Ahn, Y., Kim, Y. J., Stadtman, E. R., & Rhee, S. G. (2004) · Proceedings of the National Academy of Sciences

Redox biology and oxidative stressPI3K/AKT/mTOR signaling in cancer

Cited by 631

Peroxiredoxin functions as a peroxidase and a regulator and sensor of local peroxides

Rhee, S. G., Woo, H. A., Kil, I. S., & Bae, S. H. (2012) · Journal of Biological Chemistry

Redox biology and oxidative stressNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 603

Sestrins activate Nrf2 by promoting p62-dependent autophagic degradation of Keap1 and prevent oxidative liver damage

Bae, S. H., Sung, S. H., Oh, S. Y., Lim, J. M., Lee, S. K., Park, Y. N., Lee, H. E., Kang, D., & Rhee, S. G. (2013) · Cell Metabolism

Genomics, phytochemicals, and oxidative stressAutophagy in Disease and Therapy

Cited by 492

Multiple Functions of Peroxiredoxins: Peroxidases, Sensors and Regulators of the Intracellular Messenger H 2 O 2 , and Protein Chaperones

Rhee, S. G., & Woo, H. A. (2011) · Antioxidants & Redox Signaling

Redox biology and oxidative stressNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 463

Inactivation of Human Peroxiredoxin I during Catalysis as the Result of the Oxidation of the Catalytic Site Cysteine to Cysteine-sulfinic Acid

Yang, K.-S., Kang, S. W., Woo, H. A., Hwang, S. C., Chae, H. Z., Kim, K., & Rhee, S. G. (2002) · Journal of Biological Chemistry

Redox biology and oxidative stressGlutathione Transferases and Polymorphisms

Cited by 458

Discrete Generation of Superoxide and Hydrogen Peroxide by T Cell Receptor Stimulation

Devadas, S., Zaritskaya, L., Rhee, S. G., Oberley, L., & Williams, M. S. (2002) · The Journal of Experimental Medicine

Redox biology and oxidative stressNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 458

Regulation of PDGF signalling and vascular remodelling by peroxiredoxin II

Choi, M. H., Lee, I. K., Kim, G. W., Kim, B. U., Han, Y.-H., Yu, D.-Y., Park, H. S., Kim, K. Y., Lee, J. S., Choi, C., et al. (2005) · Nature

Redox biology and oxidative stressNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 403

Characterization of three isoforms of mammalian peroxiredoxin that reduce peroxides in the presence of thioredoxin

Chae, H. Z., Kim, H. J., Kang, S. W., & Rhee, S. G. (1999) · Diabetes Research and Clinical Practice

Redox biology and oxidative stressSelenium in Biological Systems

Cited by 390

Peroxiredoxin III, a Mitochondrion-specific Peroxidase, Regulates Apoptotic Signaling by Mitochondria

Chang, T.-S., Cho, C.-S., Park, S., Yu, S., Kang, S. W., & Rhee, S. G. (2004) · Journal of Biological Chemistry

Redox biology and oxidative stressCell death mechanisms and regulation

Cited by 388

Characterization of Mammalian Sulfiredoxin and Its Reactivation of Hyperoxidized Peroxiredoxin through Reduction of Cysteine Sulfinic Acid in the Active Site to Cysteine

Chang, T.-S., Jeong, W., Woo, H. A., Lee, S. M., Park, S., & Rhee, S. G. (2004) · Journal of Biological Chemistry

Redox biology and oxidative stressSulfur Compounds in Biology

Cited by 388

Controlled Elimination of Intracellular H 2 O2: Regulation of Peroxiredoxin, Catalase, and Glutathione Peroxidase via Post-translational Modification

Rhee, S. G., Yang, K.-S., Kang, S. W., Woo, H. A., & Chang, T.-S. (2005) · Antioxidants & Redox Signaling

Redox biology and oxidative stressGlutathione Transferases and Polymorphisms

Cited by 376

Activation of Phospholipase C-γ by Phosphatidylinositol 3,4,5-Trisphosphate

Bae, Y. S., Cantley, L. G., Chen, C.-S., Kim, S.-R., Kwon, K.-S., & Rhee, S. G. (1998) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR signaling in cancer

Cited by 330

Tyrosine phosphorylation of phospholipase C-gamma 1 induced by cross-linking of the high-affinity or low-affinity Fc receptor for IgG in U937 cells.

Liao, F., Shin, H. S., & Rhee, S. G. (1992) · Proceedings of the National Academy of Sciences

Monoclonal and Polyclonal Antibodies ResearchProtein Kinase Regulation and GTPase Signaling

Cited by 144

The antioxidant function of sestrins is mediated by promotion of autophagic degradation of Keap1 and Nrf2 activation and by inhibition of mTORC1

Rhee, S. G., & Bae, S. H. (2015) · Free Radical Biology and Medicine

Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress

Cited by 141

Mechanism of B-Cell Receptor-Induced Phosphorylation and Activation of Phospholipase C-γ2

Kim, Y. J., Sekiya, F., Poulin, B., Bae, Y. S., & Rhee, S. G. (2004) · Molecular and Cellular Biology

Protein Kinase Regulation and GTPase SignalingT-cell and B-cell Immunology

Cited by 126

Concerted Action of Sulfiredoxin and Peroxiredoxin I Protects Against Alcohol-Induced Oxidative Injury in Mouse Liver σ

Bae, S. H., Sung, S. H., Cho, E. J., Lee, S. K., Lee, H. E., Woo, H. A., Yu, D.-Y., Kil, I. S., & Rhee, S. G. (2011) · Hepatology

Redox biology and oxidative stressAlcohol Consumption and Health Effects

Cited by 93