Kaarniranta, Kai

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 5,894

FinnGen provides genetic insights from a well-phenotyped isolated population

Kurki, M. I., Karjalainen, J., Palta, P., Sipilä, T. P., Kristiansson, K., Donner, K. M., Reeve, M. P., Laivuori, H., Aavikko, M., Kaunisto, M. A., et al. (2023) · Nature

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 4,233

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 3,996

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 2,897

New insights into the genetic etiology of Alzheimer’s disease and related dementias

Bellenguez, C., Küçükali, F., Jansen, I. E., Kleineidam, L., Moreno-Grau, S., Amin, N., Naj, A. C., Campos-Martin, R., Grenier-Boley, B., Andrade, V., et al. (2022) · Nature Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 2,498

AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan

Salminen, A., Hyttinen, J. M. T., & Kaarniranta, K. (2011) · Journal of Molecular Medicine

Metabolism, Diabetes, and CancerNF-κB Signaling Pathways

Cited by 866

AMP-Activated Protein Kinase (AMPK) Controls the Aging Process via an Integrated Signaling Network

Salminen, A., & Kaarniranta, K. (2012) · Ageing Research Reviews

Metabolism, Diabetes, and CancerGenetics, Aging, and Longevity in Model Organisms

Cited by 860

Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)

Salminen, A., Kauppinen, A., & Kaarniranta, K. (2012) · Cellular Signalling

Telomeres, Telomerase, and SenescenceNF-κB Signaling Pathways

Cited by 763

Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging

Salminen, A., Huuskonen, J., Ojala, J., Kauppinen, A., Kaarniranta, K., & Suuronen, T. (2008) · Ageing Research Reviews

NF-κB Signaling PathwaysGenetics, Aging, and Longevity in Model Organisms

Cited by 581

Photoaging: UV radiation-induced inflammation and immunosuppression accelerate the aging process in the skin

Salminen, A., Kaarniranta, K., & Kauppinen, A. (2022) · Inflammation Research

Skin Protection and AgingGenetics, Aging, and Longevity in Model Organisms

Cited by 432

Terpenoids: natural inhibitors of NF-κB signaling with anti-inflammatory and anticancer potential

Salminen, A., Lehtonen, M., Suuronen, T., Kaarniranta, K., & Huuskonen, J. (2008) · Cellular and Molecular Life Sciences

Sesquiterpenes and Asteraceae StudiesNatural Compounds in Disease Treatment

Cited by 406

Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype: Astrocyte senescence in aging brain

Salminen, A., Ojala, J., Kaarniranta, K., Haapasalo, A., Hiltunen, M., & Soininen, H. (2011) · European Journal of Neuroscience

Telomeres, Telomerase, and SenescenceNeuroinflammation and Neurodegeneration Mechanisms

Cited by 333

Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration

Kaarniranta, K., Sinha, D., Blasiak, J., Kauppinen, A., Veréb, Z., Salminen, A., Boulton, M. E., & Petrovski, G. (2013) · Autophagy

Retinal Diseases and TreatmentsAutophagy in Disease and Therapy

Cited by 326

Regulation of the aging process by autophagy.

Salminen, A., & Kaarniranta, K. (2009) · Trends in Molecular Medicine

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 270

Age-related macular degeneration (AMD): Alzheimer's disease in the eye?

Kaarniranta, K., Salminen, A., Haapasalo, A., Soininen, H., & Hiltunen, M. (2011) · Journal of Alzheimer s Disease

Retinal Diseases and TreatmentsAlzheimer's disease research and treatments

Cited by 248

Defects in retinal pigment epithelial cell proteolysis and the pathology associated with age-related macular degeneration.

Ferrington, D. A., Sinha, D., & Kaarniranta, K. (2016) · Progress in Retinal and Eye Research

Retinal Diseases and TreatmentsAutophagy in Disease and Therapy

Cited by 241

Insulin/IGF-1 paradox of aging: Regulation via AKT/IKK/NF-κB signaling

Salminen, A., & Kaarniranta, K. (2010) · Cellular Signalling

Genetics, Aging, and Longevity in Model OrganismsNF-κB Signaling Pathways

Cited by 177

Beclin 1 interactome controls the crosstalk between apoptosis, autophagy and inflammasome activation: Impact on the aging process

Salminen, A., Kaarniranta, K., & Kauppinen, A. (2013) · Ageing Research Reviews

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 173

Apoptosis and aging: increased resistance to apoptosis enhances the aging process

Salminen, A., Ojala, J., & Kaarniranta, K. (2011) · Cellular and Molecular Life Sciences

Cell death mechanisms and regulationGenetics, Aging, and Longevity in Model Organisms

Cited by 158

Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease

Salminen, A., Kaarniranta, K., Haapasalo, A., Hiltunen, M., Soininen, H., & Alafuzoff, I. (2012) · Progress in Neurobiology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 153

Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy‐mediated proteolysis in human retinal pigment epithelial cells

Ryhänen, T., Hyttinen, J. M. T., Kopitz, J., Rilla, K., Kuusisto, E., Mannermaa, E., Viiri, J., Holmberg, C. I., Immonen, I., Meri, S., et al. (2009) · Journal of Cellular and Molecular Medicine

Heat shock proteins researchAutophagy in Disease and Therapy

Cited by 131

Regulation of longevity by FGF21: interaction between energy metabolism and stress responses

Salminen, A., Kaarniranta, K., & Kauppinen, A. (2017) · Ageing Research Reviews

Fibroblast Growth Factor ResearchGenetics, Aging, and Longevity in Model Organisms

Cited by 121

PGC-1α protects RPE cells of the aging retina against oxidative stress-induced degeneration through the regulation of senescence and mitochondrial quality control. The significance for AMD pathogenesis

Kaarniranta, K., Kajdanek, J., Morawiec, J., Pawlowska, E., & Blasiak, J. (2018) · International Journal of Molecular Sciences

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 112

Control of p53 and NF-κB signaling by WIP1 and MIF: Role in cellular senescence and organismal aging

Salminen, A., & Kaarniranta, K. (2011) · Cellular Signalling

Telomeres, Telomerase, and SenescenceNF-κB Signaling Pathways

Cited by 111