Ito, Yoshiaki

Everolimus plus exemestane for hormone-receptor-positive, human epidermal growth factor receptor-2-negative advanced breast cancer: overall survival results from BOLERO-2

Piccart, M., Hortobagyi, G. N., Campone, M., Pritchard, K. I., Lebrun, F., Ito, Y., Noguchi, S., Perez, A., Rugo, H. S., Deleu, I., et al. (2014) · Annals of Oncology

Advanced Breast Cancer TherapiesBreast Cancer Treatment Studies

Cited by 574

Molecular Cloning and Characterization of PEBP2β, the Heterodimeric Partner of a Novel Drosophila runt-Related DNA Binding Protein PEBP2α

Ogawa, E., Inuzuka, M., Maruyama, M., Satake, M., Naito-Fujimoto, M., Ito, Y., & Shigesada, K. (1993) · Virology

Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation

Cited by 493

The RUNX family: developmental regulators in cancer

Ito, Y., Bae, S.-C., & Chuang, L. S. H. (2015) · Nature Reviews Cancer

Cancer-related Molecular PathwaysGenomics and Chromatin Dynamics

Cited by 399

The runt domain identifies a new family of heterometric transcriptional regulators

Kagoshima, H., Shigesada, K., Satake, M., Ito, Y., Miyoshi, H., Ohki, M., Pepling, M., & Gergen, P. (1993) · Trends in Genetics

Bone Metabolism and DiseasesDevelopmental Biology and Gene Regulation

Cited by 326

RUNX transcription factors as key targets of TGF-β superfamily signaling

Ito, Y., & Miyazono, K. (2003) · Current Opinion in Genetics & Development

TGF-β signaling in diseasesDevelopmental Biology and Gene Regulation

Cited by 324

Dimerization with PEBP2β protects RUNX1/AML1 from ubiquitin–proteasome‐mediated degradation

Huang, G., Shigesada, K., Ito, K., Wee, H., Yokomizo, T., & Ito, Y. (2001) · The EMBO Journal

Acute Myeloid Leukemia ResearchUbiquitin and proteasome pathways

Cited by 283

Heterozygous PU.1 mutations are associated with acute myeloid leukemia

Mueller, B. U., Pabst, T., Osato, M., Asou, N., Johansen, L. M., Minden, M. D., Behre, G., Hiddemann, W., Ito, Y., & Tenen, D. G. (2002) · Blood

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 243

Molecular basis of aromatase deficiency in an adult female with sexual infantilism and polycystic ovaries

Ito, Y., Fisher, C. R., Conte, F. A., Grumbach, M. M., & Simpson, E. R. (1993) · Proceedings of the National Academy of Sciences

Sexual Differentiation and DisordersOvarian function and disorders

Cited by 218

RUNX Genes in Development and Cancer: Regulation of Viral Gene Expression and the Discovery of RUNX Family Genes

Ito, Y. (2008) · Advances in Cancer Research

Genomics and Chromatin DynamicsAcute Myeloid Leukemia Research

Cited by 203

Intrinsic Transcriptional Activation-Inhibition Domains of the Polyomavirus Enhancer Binding Protein 2/Core Binding Factor α Subunit Revealed in the Presence of the β Subunit

Kanno, T., Kanno, Y., Chen, L.-F., Ogawa, E., Kim, W.-Y., & Ito, Y. (1998) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsAcute Myeloid Leukemia Research

Cited by 192

Requirement of Runx1/AML1/PEBP2αB for the generation of haematopoietic cells from endothelial cells

Yokomizo, T., Ogawa, M., Osato, M., Kanno, T., Yoshida, H., Fujimoto, T., Fraser, S., Nishikawa, S., Okada, H., Satake, M., et al. (2001) · Genes to Cells

Hematopoietic Stem Cell TransplantationDevelopmental Biology and Gene Regulation

Cited by 176

Cloning, mapping and expression of PEBP2αC, a third gene encoding the mammalian Runt domain

Bae, S.-C., Takahashi, E.-I., Zhang, Y. W., Ogawa, E., Shigesada, K., Namba, Y., Satake, M., & Ito, Y. (1995) · Gene

Acute Myeloid Leukemia ResearchGenomics and Chromatin Dynamics

Cited by 158

MEK–ERK pathway regulates EZH2 overexpression in association with aggressive breast cancer subtypes

Fujii, S., Tokita, K., Wada, N., Ito, K., Yamauchi, C., Ito, Y., & Ochiai, A. (2011) · Oncogene

Epigenetics and DNA MethylationCancer-related gene regulation

Cited by 137

Subcellular Localization of the α and β Subunits of the Acute Myeloid Leukemia-Linked Transcription Factor PEBP2/CBF

Lu, J., Maruyama, M., Satake, M., Bae, S.-C., Ogawa, E., Kagoshima, H., Shigesada, K., & Ito, Y. (1995) · Molecular and Cellular Biology

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 110

Functional Dissection of the α and β Subunits of Transcription Factor PEBP2 and the Redox Susceptibility of Its DNA Binding Activity

Kagoshima, H., Akamatsu, Y., Ito, Y., & Shigesada, K. (1996) · Journal of Biological Chemistry

Genomics and Chromatin DynamicsAcute Myeloid Leukemia Research

Cited by 92

Runx1 is involved in primitive erythropoiesis in the mouse

Yokomizo, T., Hasegawa, K., Ishitobi, H., Osato, M., Ema, M., Ito, Y., Yamamoto, M., & Takahashi, S. (2008) · Blood

Hematopoietic Stem Cell TransplantationKruppel-like factors research

Cited by 78

A Novel Transcript Encoding an N-Terminally Truncated AML1/PEBP2αB Protein Interferes with Transactivation and Blocks Granulocytic Differentiation of 32Dcl3 Myeloid Cells

Zhang, Y.-W., Bae, S.-C., Huang, G., Fu, Y.-X., Lu, J., Ahn, M.-Y., Kanno, Y., Kanno, T., & Ito, Y. (1997) · Molecular and Cellular Biology

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 77

RUNX3 regulates cell cycle-dependent chromatin dynamics by functioning as a pioneer factor of the restriction-point

Lee, J.-W., Kim, D.-M., Jang, J.-W., Park, T.-G., Song, S.-H., Lee, Y.-S., Chi, X.-Z., Park, I. Y., Hyun, J.-W., Ito, Y., et al. (2019) · Nature Communications

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 57

PEBP2αB/Mouse AML1 Consists of Multiple Isoforms That Possess Differential Transactivation Potentials

Bae, S.-C., Ogawa, E., Maruyama, M., Oka, H., Satake, M., Shigesada, K., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., & Ito, Y. (1994) · Molecular and Cellular Biology

Acute Myeloid Leukemia ResearchGenomics and Chromatin Dynamics

Cited by 52

RAS oncogenic signal upregulates EZH2 in pancreatic cancer

Fujii, S., Fukamachi, K., Tsuda, H., Ito, K., Ito, Y., & Ochiai, A. (2012) · Biochemical and Biophysical Research Communications

Protein Kinase Regulation and GTPase SignalingPancreatic and Hepatic Oncology Research

Cited by 38