Gan, Wen-Biao

ATP mediates rapid microglial response to local brain injury in vivo

Davalos, D., Grutzendler, J., Yang, G., Kim, J. V., Zuo, Y., Jung, S., Littman, D. R., Dustin, M. L., & Gan, W.-B. (2005) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsAdenosine and Purinergic Signaling

Cited by 3,913

Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor

Parkhurst, C. N., Yang, G., Ninan, I., Savas, J. N., Yates, J. R., Lafaille, J. J., Hempstead, B. L., Littman, D. R., & Gan, W.-B. (2013) · Cell

Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research

Cited by 2,599

The P2Y12 receptor regulates microglial activation by extracellular nucleotides

Haynes, S. E., Hollopeter, G., Yang, G., Kurpius, D., Dailey, M. E., Gan, W.-B., & Julius, D. (2006) · Nature Neuroscience

Adenosine and Purinergic SignalingNeuroinflammation and Neurodegeneration Mechanisms

Cited by 1,542

Long-term dendritic spine stability in the adult cortex

Grutzendler, J., Kasthuri, N., & Gan, W.-B. (2002) · Nature

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 1,198

Stably maintained dendritic spines are associated with lifelong memories

Yang, G., Pan, F., & Gan, W.-B. (2009) · Nature

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 1,182

Development of long-term dendritic spine stability in diverse regions of cerebral cortex

Zuo, Y., Lin, A., Chang, P., & Gan, W.-B. (2005) · Neuron

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 684

Sleep promotes branch-specific formation of dendritic spines after learning

Yang, G., Lai, C. S. W., Cichon, J., Ma, L., Li, W., & Gan, W.-B. (2014) · Science

Sleep and Wakefulness ResearchMemory and Neural Mechanisms

Cited by 616

Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches

Tsai, J., Grutzendler, J., Duff, K., & Gan, W.-B. (2004) · Nature Neuroscience

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 561

REM sleep selectively prunes and maintains new synapses in development and learning

Li, W., Ma, L., Yang, G., & Gan, W.-B. (2017) · Nature Neuroscience

Sleep and Wakefulness ResearchNeuroscience and Neuropharmacology Research

Cited by 543

Long-term sensory deprivation prevents dendritic spine loss in primary somatosensory cortex

Zuo, Y., Yang, G., Kwon, E., & Gan, W.-B. (2005) · Nature

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 436

Opposite effects of fear conditioning and extinction on dendritic spine remodelling.

Lai, C. S. W., Franke, T. F., & Gan, W.-B. (2012) · Nature

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 392

Dendritic Spine Dynamics

Bhatt, D. H., Zhang, S., & Gan, W.-B. (2009) · Annual Review of Physiology

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 380

Circadian glucocorticoid oscillations promote learning-dependent synapse formation and maintenance.

Liston, C., Cichon, J. M., Jeanneteau, F., Jia, Z., Chao, M. V., & Gan, W.-B. (2013) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 358

Glucocorticoids are critical regulators of dendritic spine development and plasticity in vivo

Liston, C., & Gan, W.-B. (2011) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchStress Responses and Cortisol

Cited by 352

Microglia and monocytes synergistically promote the transition from acute to chronic pain after nerve injury

Peng, J., Gu, N., Zhou, L., B Eyo, U., Murugan, M., Gan, W.-B., & Wu, L.-J. (2016) · Nature Communications

Pain Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 300

Defective Neuromuscular Synapses in Mice Lacking Amyloid Precursor Protein (APP) and APP-Like Protein 2

Wang, P., Yang, G., Mosier, D. R., Chang, P., Zaidi, T., Gong, Y.-D., Zhao, N.-M., Dominguez, B., Lee, K.-F., Gan, W.-B., et al. (2005) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 290

Dendritic spine instability and insensitivity to modulation by sensory experience in a mouse model of fragile X syndrome

Pan, F., Aldridge, G. M., Greenough, W. T., & Gan, W.-B. (2010) · Proceedings of the National Academy of Sciences

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 208

Apolipoprotein E isoform-specific regulation of dendritic spine morphology in apolipoprotein E transgenic mice and Alzheimer's disease patients

Ji, Y., Gong, Y., Gan, W., Beach, T., Holtzman, D. M., & Wisniewski, T. (2003) · Neuroscience

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 189

Microglia limit the expansion of β-amyloid plaques in a mouse model of Alzheimer’s disease

Zhao, R., Hu, W., Tsai, J., Li, W., & Gan, W.-B. (2017) · Molecular Neurodegeneration

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 151

Microglia dynamics and function in the CNS

Parkhurst, C. N., & Gan, W.-B. (2010) · Current Opinion in Neurobiology

Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research

Cited by 132

The Pattern of Cortical Dysfunction in a Mouse Model of a Schizophrenia-Related Microdeletion

Fénelon, K., Xu, B., Lai, C. S., Mukai, J., Markx, S., Stark, K. L., Hsu, P.-K., Gan, W.-B., Fischbach, G. D., MacDermott, A. B., et al. (2013) · The Journal of Neuroscience

Schizophrenia research and treatmentNeuroscience and Neuropharmacology Research

Cited by 116

Synaptic dynamism measured over minutes to months: Age-dependent decline in an autonomic ganglion

Gan, W.-B., Kwon, E., Feng, G., Sanes, J. R., & Lichtman, J. W. (2003) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 84

Specific depletion of resident microglia in the early stage of stroke reduces cerebral ischemic damage

Li, T., Zhao, J., Xie, W., Yuan, W., Guo, J., Pang, S., Gan, W.-B., Gómez-Nicola, D., & Zhang, S. (2021) · Journal of Neuroinflammation

Neuroinflammation and Neurodegeneration MechanismsAcute Ischemic Stroke Management

Cited by 72