Richman, Susan D.

Mismatch Repair Status and BRAF Mutation Status in Metastatic Colorectal Cancer Patients: A Pooled Analysis of the CAIRO, CAIRO2, COIN, and FOCUS Studies

Venderbosch, S., Nagtegaal, I. D., Maughan, T. S., Smith, C. G., Cheadle, J. P., Fisher, D., Kaplan, R., Quirke, P., Seymour, M. T., Richman, S. D., et al. (2014) · Clinical Cancer Research

Colorectal Cancer Treatments and StudiesGenetic factors in colorectal cancer

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KRAS and BRAF Mutations in Advanced Colorectal Cancer Are Associated With Poor Prognosis but Do Not Preclude Benefit From Oxaliplatin or Irinotecan: Results From the MRC FOCUS Trial

Richman, S. D., Seymour, M. T., Chambers, P., Elliott, F., Daly, C. L., Meade, A. M., Taylor, G., Barrett, J. H., & Quirke, P. (2009) · Journal of Clinical Oncology

Colorectal Cancer Treatments and StudiesColorectal Cancer Surgical Treatments

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Clinical-Grade Detection of Microsatellite Instability in Colorectal Tumors by Deep Learning

Echle, A., Grabsch, H. I., Quirke, P., van den Brandt, P. A., West, N. P., Hutchins, G. G. A., Heij, L. R., Tan, X., Richman, S. D., Krause, J., et al. (2020) · Gastroenterology

Genetic factors in colorectal cancerAI in cancer detection

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Transformer-based biomarker prediction from colorectal cancer histology: A large-scale multicentric study

Wagner, S. J., Reisenbüchler, D., West, N. P., Niehues, J. M., Zhu, J., Foersch, S., Veldhuizen, G. P., Quirke, P., Grabsch, H. I., van den Brandt, P. A., et al. (2023) · Cancer Cell

AI in cancer detectionRadiomics and Machine Learning in Medical Imaging

Cited by 275

Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning

Sirinukunwattana, K., Domingo, E., Richman, S. D., Redmond, K. L., Blake, A., Verrill, C., Leedham, S. J., Chatzipli, A., Hardy, C., Whalley, C. M., et al. (2021) · Gut

AI in cancer detectionRadiomics and Machine Learning in Medical Imaging

Cited by 264

HER2 overexpression and amplification as a potential therapeutic target in colorectal cancer: analysis of 3256 patients enrolled in the QUASAR , FOCUS and PICCOLO colorectal cancer trials

Richman, S. D., Southward, K., Chambers, P., Cross, D., Barrett, J., Hemmings, G., Taylor, M., Wood, H., Hutchins, G., Foster, J. M., et al. (2016) · The Journal of Pathology

Colorectal Cancer Treatments and StudiesHER2/EGFR in Cancer Research

Cited by 241

Combined Epiregulin and Amphiregulin Expression Levels as a Predictive Biomarker for Panitumumab Therapy Benefit or Lack of Benefit in Patients With RAS Wild-Type Advanced Colorectal Cancer

Seligmann, J. F., Elliott, F., Richman, S. D., Jacobs, B., Hemmings, G., Brown, S., Barrett, J. H., Tejpar, S., Quirke, P., & Seymour, M. T. (2016) · JAMA Oncology

Colorectal Cancer Treatments and StudiesHER2/EGFR in Cancer Research

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Artificial intelligence for detection of microsatellite instability in colorectal cancer—a multicentric analysis of a pre-screening tool for clinical application

Echle, A., Ghaffari Laleh, N., Quirke, P., Grabsch, H. I., Muti, H. S., Saldanha, O. L., Brockmoeller, S. F., van den Brandt, P. A., Hutchins, G. G. A., Richman, S. D., et al. (2022) · ESMO Open

AI in cancer detectionGenetic factors in colorectal cancer

Cited by 111

Cancer-cell intrinsic gene expression signatures overcome intratumoural heterogeneity bias in colorectal cancer patient classification

Dunne, P. D., Alderdice, M., O'Reilly, P. G., Roddy, A. C., McCorry, A. M. B., Richman, S., Maughan, T., McDade, S. S., Johnston, P. G., Longley, D. B., et al. (2017) · Nature Communications

Gene expression and cancer classificationColorectal Cancer Treatments and Studies

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Intra-tumoral Heterogeneity of KRAS and BRAF Mutation Status in Patients with Advanced Colorectal Cancer (aCRC) and Cost-Effectiveness of Multiple Sample Testing

Richman, S. D., Chambers, P., Seymour, M. T., Daly, C., Grant, S., Hemmings, G., & Quirke, P. (2011) · Analytical Cellular Pathology

Colorectal Cancer Treatments and StudiesCancer Genomics and Diagnostics

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Association of Tumor HER3 Messenger RNA Expression With Panitumumab Efficacy in Advanced Colorectal Cancer

Seligmann, J. F., Hatch, A. J., Richman, S. D., Elliott, F., Jacobs, B., Brown, S., Hurwitz, H., Barrett, J. H., Quirke, P., Nixon, A. B., et al. (2018) · JAMA Oncology

Colorectal Cancer Treatments and StudiesHER2/EGFR in Cancer Research

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Activation of innate-adaptive immune machinery by poly(I:C) exposes a therapeutic vulnerability to prevent relapse in stroma-rich colon cancer

Corry, S. M., McCorry, A. M., Lannagan, T. R., Leonard, N. A., Fisher, N. C., Byrne, R. M., Tsantoulis, P., Cortes-Lavaud, X., Amirkhah, R., Redmond, K. L., et al. (2022) · Gut

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

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