Kaiser, Markus

BacPROTACs mediate targeted protein degradation in bacteria

Morreale, F. E., Kleine, S., Leodolter, J., Junker, S., Hoi, D. M., Ovchinnikov, S., Okun, A., Kley, J., Kurzbauer, R., Junk, L., et al. (2022) · Cell

Protein Degradation and InhibitorsHeat shock proteins research

Cited by 196

Structure-based evolution of a promiscuous inhibitor to a selective stabilizer of protein–protein interactions

Sijbesma, E., Visser, E., Plitzko, K., Thiel, P., Milroy, L.-G., Kaiser, M., Brunsveld, L., & Ottmann, C. (2020) · Nature Communications

14-3-3 protein interactionsComputational Drug Discovery Methods

Cited by 72

Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis

Dorsch, M., Kowalczyk, M., Planque, M., Heilmann, G., Urban, S., Dujardin, P., Forster, J., Ueffing, K., Nothdurft, S., Oeck, S., et al. (2021) · Cell Reports

Cancer, Lipids, and MetabolismCancer Cells and Metastasis

Cited by 55

From dolastatin 13 to cyanopeptolins, micropeptins, and lyngbyastatins: the chemical biology of Ahp-cyclodepsipeptides

Köcher, S., Resch, S., Kessenbrock, T., Schrapp, L., Ehrmann, M., & Kaiser, M. (2020) · Natural Product Reports

Microbial Natural Products and BiosynthesisChemical Synthesis and Analysis

Cited by 41

A modular DNA origami nanocompartment for engineering a cell-free, protein unfolding and degradation pathway

Huang, J., Jaekel, A., van den Boom, J., Podlesainski, D., Elnaggar, M., Heuer-Jungemann, A., Kaiser, M., Meyer, H., & Saccà, B. (2024) · Nature Nanotechnology

Advanced biosensing and bioanalysis techniquesNanopore and Nanochannel Transport Studies

Cited by 35

Subtilase SBT5.2 inactivates flagellin immunogenicity in the plant apoplast

Buscaill, P., Sanguankiattichai, N., Kaschani, F., Huang, J., Mooney, B. C., Li, Y., Lyu, J., Sueldo, D., Kaiser, M., & van der Hoorn, R. A. L. (2024) · Nature Communications

Plant-Microbe Interactions and ImmunityImmune Response and Inflammation

Cited by 24

Microtubule end-on attachment maturation regulates Mps1 association with its kinetochore receptor

Pleuger, R., Cozma, C., Hohoff, S., Denkhaus, C., Dudziak, A., Kaschani, F., Kaiser, M., Musacchio, A., Vetter, I. R., & Westermann, S. (2024) · Current Biology

Microtubule and mitosis dynamicsGenomics and Chromatin Dynamics

Cited by 22

TopBP1 utilises a bipartite GINS binding mode to support genome replication

Day, M., Tetik, B., Parlak, M., Almeida-Hernández, Y., Räschle, M., Kaschani, F., Siegert, H., Marko, A., Sanchez-Garcia, E., Kaiser, M., et al. (2024) · Nature Communications

DNA Repair MechanismsGenomics and Chromatin Dynamics

Cited by 14