Jain, Rajan

Repair and Regeneration of the Respiratory System: Complexity, Plasticity, and Mechanisms of Lung Stem Cell Function

Hogan, B. L. M., Barkauskas, C. E., Chapman, H. A., Epstein, J. A., Jain, R., Hsia, C. C. W., Niklason, L., Calle, E., Le, A., Randell, S. H., et al. (2014) · Cell Stem Cell

Neonatal Respiratory Health ResearchTissue Engineering and Regenerative Medicine

Cited by 876

Targeting cardiac fibrosis with engineered T cells

Aghajanian, H., Kimura, T., Rurik, J. G., Hancock, A. S., Leibowitz, M. S., Li, L., Scholler, J., Monslow, J., Lo, A., Han, W., et al. (2019) · Nature

Cardiac Fibrosis and RemodelingCongenital heart defects research

Cited by 801

Plasticity of Hopx(+) type I alveolar cells to regenerate type II cells in the lung

Jain, R., Barkauskas, C. E., Takeda, N., Bowie, E. J., Aghajanian, H., Wang, Q., Padmanabhan, A., Manderfield, L. J., Gupta, M., Li, D., et al. (2015) · Nature Communications

Neonatal Respiratory Health ResearchLiver physiology and pathology

Cited by 303

A Common Embryonic Origin of Stem Cells Drives Developmental and Adult Neurogenesis

Berg, D. A., Su, Y., Jimenez-Cyrus, D., Patel, A., Huang, N., Morizet, D., Lee, S., Shah, R., Ringeling, F. R., Jain, R., et al. (2019) · Cell

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 267

A transcriptional switch governs fibroblast activation in heart disease

Alexanian, M., Przytycki, P. F., Micheletti, R., Padmanabhan, A., Ye, L., Travers, J. G., Gonzalez-Teran, B., Silva, A. C., Duan, Q., Ranade, S. S., et al. (2021) · Nature

Cardiac Fibrosis and RemodelingCongenital heart defects research

Cited by 238

In utero CRISPR-mediated therapeutic editing of metabolic genes

Rossidis, A. C., Stratigis, J. D., Chadwick, A. C., Hartman, H. A., Ahn, N. J., Li, H., Singh, K., Coons, B. E., Li, L., Lv, W., et al. (2018) · Nature Medicine

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 216

Chromatin remodelling drives immune cell–fibroblast communication in heart failure

Alexanian, M., Padmanabhan, A., Nishino, T., Travers, J. G., Ye, L., Pelonero, A., Lee, C. Y., Sadagopan, N., Huang, Y., Auclair, K., et al. (2024) · Nature

Cardiac Fibrosis and RemodelingCongenital heart defects research

Cited by 140

Ionizable Lipid Nanoparticles for Therapeutic Base Editing of Congenital Brain Disease

Palanki, R., Bose, S. K., Dave, A., White, B. M., Berkowitz, C., Luks, V., Yaqoob, F., Han, E., Swingle, K. L., Menon, P., et al. (2023) · ACS Nano

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 77

In utero adenine base editing corrects multi-organ pathology in a lethal lysosomal storage disease

Bose, S. K., White, B. M., Kashyap, M. V., Dave, A., De Bie, F. R., Li, H., Singh, K., Menon, P., Wang, T., Teerdhala, S., et al. (2021) · Nature Communications

Lysosomal Storage Disorders ResearchVirus-based gene therapy research

Cited by 67

BRD4 (Bromodomain-Containing Protein 4) Interacts with GATA4 (GATA Binding Protein 4) to Govern Mitochondrial Homeostasis in Adult Cardiomyocytes

Padmanabhan, A., Alexanian, M., Linares-Saldana, R., González-Terán, B., Andreoletti, G., Huang, Y., Connolly, A. J., Kim, W., Hsu, A., Duan, Q., et al. (2020) · Circulation

Protein Degradation and InhibitorsCongenital heart defects research

Cited by 60