Repair and Regeneration of the Respiratory System: Complexity, Plasticity, and Mechanisms of Lung Stem Cell Function

Identification of Bronchioalveolar Stem Cells in Normal Lung and Lung Cancer

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Type 2 alveolar cells are stem cells in adult lung

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Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters

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Basal cells as stem cells of the mouse trachea and human airway epithelium

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Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq

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Tissue-Engineered Lungs for in Vivo Implantation

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Regeneration and orthotopic transplantation of a bioartificial lung

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Alveolar progenitor and stem cells in lung development, renewal and cancer

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Decreased histone deacetylase activity in chronic obstructive pulmonary disease.

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Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition

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Preparing for the First Breath: Genetic and Cellular Mechanisms in Lung Development

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PDGF-A signaling is a critical event in lung alveolar myofibroblast development and alveogenesis

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The Role of Scgb1a1+ Clara Cells in the Long-Term Maintenance and Repair of Lung Airway, but Not Alveolar, Epithelium

Rawlins, E. L., Okubo, T., Xue, Y., Brass, D. M., Auten, R. L., Hasegawa, H., Wang, F., & Hogan, B. L. M. (2009) · Cell stem cell · doi:10.1016/j.stem.2009.04.002 · Cited by 855 · see citing works

The branching programme of mouse lung development

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A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci

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Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling

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Aberrant Wnt/β-Catenin Pathway Activation in Idiopathic Pulmonary Fibrosis

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Acellular Normal and Fibrotic Human Lung Matrices as a Culture System for <i>In Vitro</i> Investigation

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Dedifferentiation of committed epithelial cells into stem cells in vivo

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Multipotent Drosophila Intestinal Stem Cells Specify Daughter Cell Fates by Differential Notch Signaling

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Lung development: orchestrating the generation and regeneration of a complex organ

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Pulmonary fibrosis: patterns and perpetrators

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Plasticity of epithelial stem cells in tissue regeneration

Blanpain, C., & Fuchs, E. (2014) · Science · doi:10.1126/science.1242281 · Cited by 589 · see citing works

Transformation of alveolar Type 2 cells to Type 1 cells following exposure to NO2

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Distal Airway Stem Cells Yield Alveoli In Vitro and during Lung Regeneration following H1N1 Influenza Infection

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Efficient generation of lung and airway epithelial cells from human pluripotent stem cells

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CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury

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Terminal Bronchioles Harbor a Unique Airway Stem Cell Population That Localizes to the Bronchoalveolar Duct Junction

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Basal Cells Are a Multipotent Progenitor Capable of Renewing the Bronchial Epithelium

Hong, K. U., Reynolds, S. D., Watkins, S. C., Fuchs, E. V., & Stripp, B. R. (2004) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)63147-1 · Cited by 540 · see citing works

Endothelial-Derived Angiocrine Signals Induce and Sustain Regenerative Lung Alveolarization

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Lung Stem Cell Differentiation in Mice Directed by Endothelial Cells via a BMP4-NFATc1-Thrombospondin-1 Axis

Lee, J., Bhang, D. H., Beede, A. M., Huang, T. L., Stripp, B. R., Bloch, K. D., Wagers, A. J., Tseng, Y., Ryeom, S. W., & Kim, C. F. (2014) · Cell · doi:10.1016/j.cell.2013.12.039 · Cited by 491 · see citing works

Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells

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Tracheal replacement: a critical review

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Inhibition of Wnt/β-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis

Henderson, W. R., Chi, E. Y., Ye, X., Nguyen, C., Tien, Y.-T., Zhou, B., Borok, Z., Knight, D. A., & Kahn, M. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1001520107 · Cited by 464 · see citing works

Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity

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Notch-Dependent Differentiation of Adult Airway Basal Stem Cells

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Renewal of alveolar epithelium in the rat following exposure to NO2.

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Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein

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Intussusceptive angiogenesis: Its emergence, its characteristics, and its significance

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Integrin α6β4 identifies an adult distal lung epithelial population with regenerative potential in mice

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SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production

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In vivo two-photon imaging reveals monocyte-dependent neutrophil extravasation during pulmonary inflammation

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Efficient Derivation of Purified Lung and Thyroid Progenitors from Embryonic Stem Cells

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Notch signaling controls the balance of ciliated and secretory cell fates in developing airways

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The Id2+ distal tip lung epithelium contains individual multipotent embryonic progenitor cells

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Stabilized imaging of immune surveillance in the mouse lung

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Development of a Decellularized Lung Bioreactor System for Bioengineering the Lung: The Matrix Reloaded

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A Genome-Wide Association Study of Pulmonary Function Measures in the Framingham Heart Study

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Generation of Multipotent Lung and Airway Progenitors from Mouse ESCs and Patient-Specific Cystic Fibrosis iPSCs

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Functional characterization of pulmonary neuroendocrine cells in lung development, injury, and tumorigenesis

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Expression and Activity of Histone Deacetylases in Human Asthmatic Airways

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Evidence for type II cells as cells of origin of K-Ras–induced distal lung adenocarcinoma

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Notch signaling promotes airway mucous metaplasia and inhibits alveolar development

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Foxp2 and Foxp1 cooperatively regulate lung and esophagus development

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A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration

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Dynamic changes in intracellular ROS levels regulate airway basal stem cell homeostasis through Nrf2-dependent Notch signaling

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Unravelling stem cell dynamics by lineage tracing

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Sox9 plays multiple roles in the lung epithelium during branching morphogenesis

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Perfusion decellularization of human and porcine lungs: Bringing the matrix to clinical scale

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Retinal pigment epithelium development, plasticity, and tissue homeostasis

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Parabronchial smooth muscle constitutes an airway epithelial stem cell niche in the mouse lung after injury

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Bronchioalveolar stem cells increase after mesenchymal stromal cell treatment in a mouse model of bronchopulmonary dysplasia

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Human iPS cell–derived alveolar epithelium repopulates lung extracellular matrix

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Coordination of heart and lung co-development by a multipotent cardiopulmonary progenitor

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Different assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cells

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The effects of mechanical forces on lung functions

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Outcomes of Liver Transplantation for Nonalcoholic Steatohepatitis: A Systematic Review and Meta-analysis

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Airway Epithelial Progenitors Are Region Specific and Show Differential Responses to Bleomycin-Induced Lung Injury

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Reversible Transdifferentiation of Alveolar Epithelial Cells

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WNT/β-Catenin Signaling Induces IL-1β Expression by Alveolar Epithelial Cells in Pulmonary Fibrosis

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Lung epithelial branching program antagonizes alveolar differentiation

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First human transplantation of a bioengineered airway tissue

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Production and Assessment of Decellularized Pig and Human Lung Scaffolds

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Mechanisms and Limits of Induced Postnatal Lung Growth

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Clinical experience with the silicone tracheal prosthesis

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Long noncoding RNAs are spatially correlated with transcription factors and regulate lung developmentPreprint

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Fgf10-positive cells represent a progenitor cell population during lung development and postnatally

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Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways

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Tracheal Basal Cells

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Dynamic Regulation of Platelet-Derived Growth Factor Receptor α Expression in Alveolar Fibroblasts during Realveolarization

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Three-dimensional scaffolds of acellular human and porcine lungs for high throughput studies of lung disease and regeneration

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Human Alveolar Wall Fibroblasts Directly Link Epithelial Type 2 Cells to Capillary Endothelium

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