Akbarian, Schahram

miR-10b-5p expression in Huntington’s disease brain relates to age of onset and the extent of striatal involvement

Hoss, A. G., Labadorf, A., Latourelle, J. C., Kartha, V. K., Hadzi, T. C., Gusella, J. F., MacDonald, M. E., Chen, J.-F., Akbarian, S., Weng, Z., et al. (2015) · BMC Medical Genomics

Genetic Neurodegenerative DiseasesMicroRNA in disease regulation

Cited by 151

Prefrontal parvalbumin interneurons require juvenile social experience to establish adult social behavior

Bicks, L. K., Yamamuro, K., Flanigan, M. E., Kim, J. M., Kato, D., Lucas, E. K., Koike, H., Peng, M. S., Brady, D. M., Chandrasekaran, S., et al. (2020) · Nature Communications

Neuroendocrine regulation and behaviorNeuroscience and Neuropharmacology Research

Cited by 150

Cell-specific histone modification maps in the human frontal lobe link schizophrenia risk to the neuronal epigenome

Girdhar, K., Hoffman, G. E., Jiang, Y., Brown, L., Kundakovic, M., Hauberg, M. E., Francoeur, N. J., Wang, Y.-C., Shah, H., Kavanagh, D. H., et al. (2018) · Nature Neuroscience

Genomics and Chromatin DynamicsSchizophrenia research and treatment

Cited by 139

Drug-Induced Activation of Dopamine D1 Receptor Signaling and Inhibition of Class I/II Histone Deacetylase Induce Chromatin Remodeling in Reward Circuitry and Modulate Cocaine-Related Behaviors

Schroeder, F. A., Penta, K. L., Matevossian, A., Jones, S. R., Konradi, C., Tapper, A. R., & Akbarian, S. (2008) · Neuropsychopharmacology

Neurotransmitter Receptor Influence on BehaviorHistone Deacetylase Inhibitors Research

Cited by 139

Neuronal Nuclei Isolation from Human Postmortem Brain Tissue

Matevossian, A., & Akbarian, S. (2008) · Journal of Visualized Experiments

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 126

Setdb1 Histone Methyltransferase Regulates Mood-Related Behaviors and Expression of the NMDA Receptor Subunit NR2B

Jiang, Y., Jakovcevski, M., Bharadwaj, R., Connor, C., Schroeder, F. A., Lin, C. L., Straubhaar, J., Martin, G., & Akbarian, S. (2010) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchTreatment of Major Depression

Cited by 118

Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders

Hu, B., Won, H., Mah, W., Park, R. B., Kassim, B., Spiess, K., Kozlenkov, A., Crowley, C. A., Pochareddy, S., The PsychENCODE Consortium, et al. (2021) · Nature Communications

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 103

Analytical tools and current challenges in the modern era of neuroepigenomics

Maze, I., Shen, L., Zhang, B., Garcia, B. A., Shao, N., Mitchell, A., Sun, H., Akbarian, S., Allis, C. D., & Nestler, E. J. (2014) · Nature Neuroscience

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 100

Disruption of an Evolutionarily Novel Synaptic Expression Pattern in Autism

Liu, X., Han, D., Somel, M., Jiang, X., Hu, H., Guijarro, P., Zhang, N., Mitchell, A., Halene, T., Ely, J. J., et al. (2016) · PLOS Biology

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 87

Conserved Higher-Order Chromatin Regulates NMDA Receptor Gene Expression and Cognition

Bharadwaj, R., Peter, C. J., Jiang, Y., Roussos, P., Vogel-Ciernia, A., Shen, E. Y., Mitchell, A. C., Mao, W., Whittle, C., Dincer, A., et al. (2014) · Neuron

Genomics and Chromatin DynamicsNeuroscience and Neuropharmacology Research

Cited by 84

The histone deacetylase inhibitor, sodium butyrate, alleviates cognitive deficits in pre-motor stage PD

Rane, P., Shields, J., Heffernan, M., Guo, Y., Akbarian, S., & King, J. A. (2012) · Neuropharmacology

Parkinson's Disease Mechanisms and TreatmentsNeurotransmitter Receptor Influence on Behavior

Cited by 78

Metabolome signature of autism in the human prefrontal cortex

Kurochkin, I., Khrameeva, E., Tkachev, A., Stepanova, V., Vanyushkina, A., Stekolshchikova, E., Li, Q., Zubkov, D., Shichkova, P., Halene, T., et al. (2019) · Communications Biology

Autism Spectrum Disorder ResearchMetabolomics and Mass Spectrometry Studies

Cited by 57

Interneuron epigenomes during the critical period of cortical plasticity: Implications for schizophrenia

Morishita, H., Kundakovic, M., Bicks, L., Mitchell, A., & Akbarian, S. (2015) · Neurobiology of Learning and Memory

Schizophrenia research and treatmentNeuroscience and Neuropharmacology Research

Cited by 42

Advancing drug discovery for schizophrenia

Marder, S. R., Roth, B., Sullivan, P. F., Scolnick, E. M., Nestler, E. J., Geyer, M. A., Welnberger, D. R., Karayiorgou, M., Guidotti, A., Gingrich, J., et al. (2011) · Annals of the New York Academy of Sciences

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 25

NeuN+ neuronal nuclei in non-human primate prefrontal cortex and subcortical white matter after clozapine exposure

Halene, T. B., Kozlenkov, A., Jiang, Y., Mitchell, A. C., Javidfar, B., Dincer, A., Park, R., Wiseman, J., Croxson, P. L., Giannaris, E. L., et al. (2016) · Schizophrenia Research

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 18

Evaluation of chromatin accessibility in prefrontal cortex of schizophrenia cases and controls

Bryois, J., Garrett, M. E., Song, L., Safi, A., Giusti-Rodriguez, P., Johnson, G. D., Demur, A. B., Fullard, J. F., Roussos, P., Sklar, P., et al. (2017) · bioRxiv (Cold Spring Harbor Laboratory)

Schizophrenia research and treatmentGenomics and Chromatin Dynamics

Cited by 7

Cognition and mood-related behaviors in L3mbtl1 null mutant mice

Shen, E. Y., Jiang, Y., Mao, W., Futai, K., Hock, H., & Akbarian, S. (2015) · PLoS ONE

Epigenetics and DNA MethylationNeurotransmitter Receptor Influence on Behavior

Cited by 4

Epitranscriptomic and Metabolomic Signatures Involved in Translational Mechanisms of Suicide and Depression

Blaze, J., Plaza-Jennings, A., Turecki, G., Haghighi, F., & Akbarian, S. (2022) · Biological Psychiatry

RNA modifications and cancerTreatment of Major Depression

Cited by 3