Zeng, Xiangxiang

Target identification among known drugs by deep learning from heterogeneous networks

Zeng, X., Zhu, S., Lu, W., Liu, Z., Huang, J., Zhou, Y., Fang, J., Huang, Y., Guo, H., Li, L., et al. (2020) · Chemical Science

Computational Drug Discovery MethodsBioinformatics and Genomic Networks

Cited by 357

Deep generative molecular design reshapes drug discovery

Zeng, X., Wang, F., Luo, Y., Kang, S.-G., Tang, J., Lightstone, F. C., Fang, E. F., Cornell, W., Nussinov, R., & Cheng, F. (2022) · Cell Reports Medicine

Computational Drug Discovery MethodsMachine Learning in Materials Science

Cited by 295

Inferring microrna-disease associations by random walk on a heterogeneous network with multiple data sources

Liu, Y., Zeng, X., He, Z., & Zou, Q. (2017) · IEEE/ACM Transactions on Computational Biology and Bioinformatics

MicroRNA in disease regulationBioinformatics and Genomic Networks

Cited by 284

Prediction of potential disease-associated microRNAs using structural perturbation method

Zeng, X., Liu, L., Lü, L., & Zou, Q. (2018) · Bioinformatics

MicroRNA in disease regulationBioinformatics and Genomic Networks

Cited by 235

Toward better drug discovery with knowledge graph

Zeng, X., Tu, X., Liu, Y., Fu, X., & Su, Y. (2022) · Current Opinion in Structural Biology

Computational Drug Discovery MethodsAdvanced Graph Neural Networks

Cited by 229

Prediction and Validation of Disease Genes Using HeteSim Scores

Zeng, X., Liao, Y., Liu, Y., & Zou, Q. (2017) · IEEE/ACM Transactions on Computational Biology and Bioinformatics

Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies

Cited by 208

GraphCPI: Graph Neural Representation Learning for Compound-Protein Interaction

Quan, Z., Guo, Y., Lin, X., Wang, Z.-J., & Zeng, X. (2019) · 2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

Computational Drug Discovery MethodsMachine Learning in Bioinformatics

Cited by 35

Exploring the conformational ensembles of protein-protein complex with transformer-based generative model

Wang, J., Wang, X., Chu, Y., Li, C., Li, X., Meng, X., Fang, Y., No, K. T., Mao, J., & Zeng, X. (2024) · Journal of Chemical Theory and Computation

Protein Structure and DynamicsComputational Drug Discovery Methods

Cited by 26