Wurst, Wolfgang

Apolipoprotein E aggregation in microglia initiates Alzheimer’s disease pathology by seeding β-amyloidosis

Kaji, S., Berghoff, S. A., Spieth, L., Schlaphoff, L., Sasmita, A. O., Vitale, S., Büschgens, L., Kedia, S., Zirngibl, M., Nazarenko, T., et al. (2024) · Immunity

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 104

Individual Stress Vulnerability Is Predicted by Short-Term Memory and AMPA Receptor Subunit Ratio in the Hippocampus

Schmidt, M. V., Trümbach, D., Weber, P., Wagner, K., Scharf, S. H., Liebl, C., Datson, N., Namendorf, C., Gerlach, T., Kühne, C., et al. (2010) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchStress Responses and Cortisol

Cited by 91

Urocortin 3 Modulates Social Discrimination Abilities via Corticotropin-Releasing Hormone Receptor Type 2

Deussing, J. M., Breu, J., Kuhne, C., Kallnik, M., Bunck, M., Glasl, L., Yen, Y.-C., Schmidt, M. V., Zurmuhlen, R., Vogl, A. M., et al. (2010) · Journal of Neuroscience

Neuroendocrine regulation and behaviorOlfactory and Sensory Function Studies

Cited by 86

The Alzheimer’s disease-associated protective Plcγ2-P522R variant promotes immune functions

Takalo, M., Wittrahm, R., Wefers, B., Parhizkar, S., Jokivarsi, K., Kuulasmaa, T., Mäkinen, P., Martiskainen, H., Wurst, W., Xiang, X., et al. (2020) · Molecular Neurodegeneration

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 83

Heterozygosity for the mood disorder-associated variant Gln460Arg alters P2X7 receptor function and sleep quality

Metzger, M. W., Walser, S. M., Dedic, N., Aprile-Garcia, F., Jakubcakova, V., Adamczyk, M., Webb, K. J., Uhr, M., Refojo, D., Schmidt, M. V., et al. (2017) · The Journal of Neuroscience

Adenosine and Purinergic SignalingNeurotransmitter Receptor Influence on Behavior

Cited by 59

Impact of IVC housing on emotionality and fear learning in male C3HeB/FeJ and C57BL/6J mice

Kallnik, M., Elvert, R., Ehrhardt, N., Kissling, D., Mahabir, E., Welzl, G., Faus-Kessler, T., de Angelis, M. H., Wurst, W., Schmidt, J., et al. (2007) · Mammalian Genome

Animal Behavior and Welfare StudiesMemory and Neural Mechanisms

Cited by 58

CRF1 and CRF2 Receptors are Required for Potentiated Startle to Contextual but not Discrete Cues

Risbrough, V. B., Geyer, M. A., Hauger, R. L., Coste, S., Stenzel-Poore, M., Wurst, W., & Holsboer, F. (2009) · Neuropsychopharmacology

Neuropeptides and Animal PhysiologyStress Responses and Cortisol

Cited by 49

A novel N‐ethyl‐N‐nitrosourea–induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model

Abe, K., Fuchs, H., Boersma, A., Hans, W., Yu, P., Kalaydjiev, S., Klaften, M., Adler, T., Calzada‐Wack, J., Mossbrugger, I., et al. (2011) · Arthritis & Rheumatism

Rheumatoid Arthritis Research and TherapiesSystemic Lupus Erythematosus Research

Cited by 46

TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism

Feiten, A. F., Dahm, K., Schlepckow, K., van Lengerich, B., Suh, J. H., Reifschneider, A., Wefers, B., Bartos, L. M., Wind-Mark, K., de Weerd, L., et al. (2026) · Nature Communications

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 39

Conditional reduction of adult born doublecortin-positive neurons reversibly impairs selective behaviors

Garrett, L., Zhang, J., Zimprich, A., Niedermeier, K. M., Fuchs, H., Gailus-Durner, V., Hrabě de Angelis, M., Vogt Weisenhorn, D., Wurst, W., & Hölter, S. M. (2015) · Frontiers in Behavioral Neuroscience

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 37

HIC2 Is a Novel Dosage-Dependent Regulator of Cardiac Development Located Within the Distal 22q11 Deletion Syndrome Region

Dykes, I. M., van Bueren, K. L., Ashmore, R. J., Floss, T., Wurst, W., Szumska, D., Bhattacharya, S., & Scambler, P. J. (2014) · Circulation Research

Congenital heart defects researchGenomic variations and chromosomal abnormalities

Cited by 33

Apolipoprotein E aggregation in microglia initiates Alzheimer’s disease pathology by seeding β-amyloidosis

Kaji, S., Berghoff, S. A., Spieth, L., Schlaphoff, L., Sasmita, A. O., Vitale, S., Büschgens, L., Kedia, S., Zirngibl, M., Nazarenko, T., et al. (2025) · Immunity

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 7