Leeuwenburgh, Christiaan

Mitochondrial death effectors: Relevance to sarcopenia and disuse muscle atrophy

Marzetti, E., Hwang, J. C. Y., Lees, H. A., Wohlgemuth, S. E., Dupont-Versteegden, E. E., Carter, C. S., Bernabei, R., & Leeuwenburgh, C. (2010) · Biochimica et Biophysica Acta (BBA) - General Subjects

Muscle Physiology and DisordersMitochondrial Function and Pathology

Cited by 174

Age-related activation of mitochondrial caspase-independent apoptotic signaling in rat gastrocnemius muscle

Marzetti, E., Wohlgemuth, S. E., Lees, H. A., Chung, H.-Y., Giovannini, S., & Leeuwenburgh, C. (2008) · Mechanisms of Ageing and Development

Mitochondrial Function and PathologyCell death mechanisms and regulation

Cited by 172

Mitochondrial DNA mutations, energy metabolism and apoptosis in aging muscle

Dirks, A. J., Hofer, T., Marzetti, E., Pahor, M., & Leeuwenburgh, C. (2006) · Ageing Research Reviews

Mitochondrial Function and PathologyMuscle Physiology and Disorders

Cited by 169

Dysregulation of mitochondrial quality control processes contribute to sarcopenia in a mouse model of premature aging.

Joseph, A.-M., Adhihetty, P. J., Wawrzyniak, N. R., Wohlgemuth, S. E., Picca, A., Kujoth, G. C., Prolla, T. A., & Leeuwenburgh, C. (2013) · PLoS ONE

Mitochondrial Function and PathologyMuscle Physiology and Disorders

Cited by 161

Circulating Mitochondrial DNA at the Crossroads of Mitochondrial Dysfunction and Inflammation During Aging and Muscle Wasting Disorders

Picca, A., Lezza, A. M. S., Leeuwenburgh, C., Pesce, V., Calvani, R., Bossola, M., Manes-Gravina, E., Landi, F., Bernabei, R., & Marzetti, E. (2018) · Rejuvenation Research

Mitochondrial Function and PathologyMuscle Physiology and Disorders

Cited by 144

Effects of Popular Diets without Specific Calorie Targets on Weight Loss Outcomes: Systematic Review of Findings from Clinical Trials

Anton, S., Hida, A., Heekin, K., Sowalsky, K., Karabetian, C., Mutchie, H., Leeuwenburgh, C., Manini, T., & Barnett, T. (2017) · Nutrients

Diet and metabolism studiesDietary Effects on Health

Cited by 125

Modulation of age-induced apoptotic signaling and cellular remodeling by exercise and calorie restriction in skeletal muscle

Marzetti, E., Lawler, J. M., Hiona, A., Manini, T., Seo, A. Y., & Leeuwenburgh, C. (2008) · Free Radical Biology and Medicine

Muscle Physiology and DisordersNutrition and Health in Aging

Cited by 113

Changes in IL-15 expression and death-receptor apoptotic signaling in rat gastrocnemius muscle with aging and life-long calorie restriction

Marzetti, E., Carter, C. S., Wohlgemuth, S. E., Lees, H. A., Giovannini, S., Anderson, B., Quinn, L. S., & Leeuwenburgh, C. (2009) · Mechanisms of Ageing and Development

Muscle Physiology and DisordersNutrition and Health in Aging

Cited by 113

Impaired iron status in aging research

Xu, J., Jia, Z., Knutson, M. D., & Leeuwenburgh, C. (2012) · International Journal of Molecular Sciences

Iron Metabolism and DisordersTrace Elements in Health

Cited by 103

Safety and metabolic outcomes of resveratrol supplementation in older adults: Results of a twelve-week, placebo-controlled pilot study

Anton, S. D., Embry, C., Marsiske, M., Lu, X., Doss, H., Leeuwenburgh, C., & Manini, T. M. (2014) · Experimental Gerontology

Sirtuins and Resveratrol in MedicinePhytochemicals and Antioxidant Activities

Cited by 95

Dietary Antioxidants as Modifiers of Physiologic Adaptations to Exercise

MANKOWSKI, R. T., ANTON, S. D., BUFORD, T. W., & LEEUWENBURGH, C. (2015) · Medicine & Science in Sports & Exercise

Exercise and Physiological ResponsesAntioxidant Activity and Oxidative Stress

Cited by 83

C-Reactive Protein Genotypes Affect Baseline, but not Exercise Training–Induced Changes, in C-Reactive Protein Levels

Obisesan, T. O., Leeuwenburgh, C., Phillips, T., Ferrell, R. E., Phares, D. A., Prior, S. J., & Hagberg, J. M. (2004) · Arteriosclerosis, Thrombosis, and Vascular Biology

Adipokines, Inflammation, and Metabolic DiseasesLipoproteins and Cardiovascular Health

Cited by 83

Chronic pain, perceived stress, and cellular aging: an exploratory study.

Sibille, K. T., Langaee, T., Burkley, B., Gong, Y., Glover, T. L., King, C., Riley, J. L., Leeuwenburgh, C., Staud, R., Bradley, L. A., et al. (2012) · Molecular Pain

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 80

Effects of Age and Sedentary Lifestyle on Skeletal Muscle NF- B Signaling in Men

Buford, T. W., Cooke, M. B., Manini, T. M., Leeuwenburgh, C., & Willoughby, D. S. (2010) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Muscle Physiology and DisordersNF-κB Signaling Pathways

Cited by 78

Dietary restriction: standing up for sirtuins

Baur, J. A., Chen, D., Chini, E. N., Chua, K., Cohen, H. Y., Cabo, R. D., Deng, C., Dimmeler, S., Gius, D., Guarente, L. P., et al. (2010) · Science

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

Cited by 76

Associations between biomarkers of cellular senescence and physical function in humans: observations from the lifestyle interventions for elders (LIFE) study

Fielding, R. A., Atkinson, E. J., Aversa, Z., White, T. A., Heeren, A. A., Achenbach, S. J., Mielke, M. M., Cummings, S. R., Pahor, M., Leeuwenburgh, C., et al. (2022) · GeroScience

Telomeres, Telomerase, and SenescenceNutrition and Health in Aging

Cited by 75

Life-long calorie restriction in Fischer 344 rats attenuates age-related loss in skeletal muscle-specific force and reduces extracellular space

Payne, A. M., Dodd, S. L., & Leeuwenburgh, C. (2003) · Journal of Applied Physiology

Muscle Physiology and DisordersGenetics, Aging, and Longevity in Model Organisms

Cited by 71

Vascular dysfunction as a potential culprit of sarcopenia

Jeon, Y. K., Shin, M. J., Saini, S. K., Custodero, C., Aggarwal, M., Anton, S. D., Leeuwenburgh, C., & Mankowski, R. T. (2021) · Experimental Gerontology

Nutrition and Health in AgingFrailty in Older Adults

Cited by 60

Effect of losartan and fish oil on plasma IL-6 and mobility in older persons.The ENRGISe pilot randomized clinical trial

Pahor, M., Anton, S. D., Beavers, D. P., Cauley, J. A., Fielding, R. A., Kritchevsky, S. B., Leeuwenburgh, C., Lewis, K. H., Liu, C. K., Lovato, L. C., et al. (2019) · The Journals of Gerontology Series A

Nutrition and Health in AgingFrailty in Older Adults

Cited by 50

Biomarkers of cellular senescence predict the onset of mobility disability and are reduced by physical activity in older adults

Fielding, R. A., Atkinson, E. J., Aversa, Z., White, T. A., Heeren, A. A., Mielke, M. M., Cummings, S. R., Pahor, M., Leeuwenburgh, C., & LeBrasseur, N. K. (2024) · The Journals of Gerontology: Series A

Telomeres, Telomerase, and SenescenceFrailty in Older Adults

Cited by 38

Short-term caloric restriction and regulatory proteins of apoptosis in heart, skeletal muscle and kidney of Fischer 344 rats

Selman, C., Gredilla, R., Phaneuf, S., Kendaiah, S., Barja, G., & Leeuwenburgh, C. (2003) · Biogerontology

Genetics, Aging, and Longevity in Model OrganismsCell death mechanisms and regulation

Cited by 24

Relationship between Mitochondrial Quality Control Markers, Lower Extremity Tissue Composition, and Physical Performance in Physically Inactive Older Adults

Picca, A., Triolo, M., Wohlgemuth, S. E., Martenson, M. S., Mankowski, R. T., Anton, S. D., Marzetti, E., Leeuwenburgh, C., & Hood, D. A. (2023) · Cells

Autophagy in Disease and TherapyMuscle Physiology and Disorders

Cited by 23