Dinarello, Charles A.

Immunoreactive interleukin-1β localization in the rat forebrain

Lechan, R. M., Toni, R., Clark, B. D., Cannon, J. G., Shaw, A. R., Dinarello, C. A., & Reichlin, S. (1990) · Brain Research

Neuroinflammation and Neurodegeneration MechanismsNeuropeptides and Animal Physiology

Cited by 340

Inflammasome-independent regulation of IL-1-family cytokines

Netea, M. G., van de Veerdonk, F. L., van der Meer, J. W. M., Dinarello, C. A., & Joosten, L. A. B. (2015) · Annual Review of Immunology

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 326

IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans

de Luca, A., Smeekens, S. P., Casagrande, A., Iannitti, R., Conway, K. L., Gresnigt, M. S., Begun, J., Plantinga, T. S., Joosten, L. A. B., van der Meer, J. W. M., et al. (2014) · Proceedings of the National Academy of Sciences

Neutrophil, Myeloperoxidase and Oxidative MechanismsImmunodeficiency and Autoimmune Disorders

Cited by 313

The NLRP3 inflammasome inhibitor OLT1177 rescues cognitive impairment in a mouse model of Alzheimer’s disease

Lonnemann, N., Hosseini, S., Marchetti, C., Skouras, D. B., Stefanoni, D., D’Alessandro, A., Dinarello, C. A., & Korte, M. (2020) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsInflammasome and immune disorders

Cited by 298

Constitutively Active Inflammasome in Human Melanoma Cells Mediating Autoinflammation via Caspase-1 Processing and Secretion of Interleukin-1β

Okamoto, M., Liu, W., Luo, Y., Tanaka, A., Cai, X., Norris, D. A., Dinarello, C. A., & Fujita, M. (2010) · Journal of Biological Chemistry

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 293

Interleukin-1β–Driven Inflammation Promotes the Development and Invasiveness of Chemical Carcinogen–Induced Tumors

Krelin, Y., Voronov, E., Dotan, S., Elkabets, M., Reich, E., Fogel, M., Huszar, M., Iwakura, Y., Segal, S., Dinarello, C. A., et al. (2007) · Cancer Research

Immune cells in cancerImmunotoxicology and immune responses

Cited by 285

Interleukin-18, more than a Th1 cytokine

Novick, D., Kim, S., Kaplanski, G., & Dinarello, C. A. (2013) · Seminars in Immunology

Cytokine Signaling Pathways and InteractionsInflammasome and immune disorders

Cited by 280

Reactive oxygen species–independent activation of the IL-1β inflammasome in cells from patients with chronic granulomatous disease

van de Veerdonk, F. L., Smeekens, S. P., Joosten, L. A. B., Kullberg, B. J., Dinarello, C. A., van der Meer, J. W. M., & Netea, M. G. (2010) · Proceedings of the National Academy of Sciences

Inflammasome and immune disordersNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 248

Insulin-like growth factor-1 and interleukin 6 predict sarcopenia in very old community-living men and women: the Framingham Heart Study

Payette, H., Roubenoff, R., Jacques, P. F., Dinarello, C. A., Wilson, P. W. F., Abad, L. W., & Harris, T. (2003) · Journal of the American Geriatrics Society

Nutrition and Health in AgingMuscle Physiology and Disorders

Cited by 245

Differences in signaling pathways by IL-1β and IL-18

Lee, J.-K., Kim, S.-H., Lewis, E. C., Azam, T., Reznikov, L. L., & Dinarello, C. A. (2004) · Proceedings of the National Academy of Sciences

Cytokine Signaling Pathways and InteractionsNF-κB Signaling Pathways

Cited by 237

Dietary supplementation with n-3 fatty acids suppresses interleukin-2 production and mononuclear cell proliferation

Endres, S., Meydani, S. N., Ghorbani, R., Schindler, R., & Dinarello, C. A. (1993) · Journal of Leukocyte Biology

Fatty Acid Research and HealthEdible Oils Quality and Analysis

Cited by 228

The role of macrophage-derived IL-1 in induction and maintenance of angiogenesis

Carmi, Y., Voronov, E., Dotan, S., Lahat, N., Rahat, M. A., Fogel, M., Huszar, M., White, M. R., Dinarello, C. A., & Apte, R. N. (2009) · The Journal of Immunology

Angiogenesis and VEGF in CancerImmune cells in cancer

Cited by 224

Therapeutic strategies to reduce IL-1 activity in treating local and systemic inflammation

DINARELLO, C. (2004) · Current Opinion in Pharmacology

Inflammasome and immune disordersRheumatoid Arthritis Research and Therapies

Cited by 195

The inflammatory response in interleukin-1β-deficient mice: comparison with other cytokine-related knock-out mice.

Fantuzzi, G., & Dinarello, C. A. (1996) · Journal of Leukocyte Biology

Immune Response and InflammationInflammasome and immune disorders

Cited by 156

Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors

Henry, C. J., Casás-Selves, M., Kim, J., Zaberezhnyy, V., Aghili, L., Daniel, A. E., Jimenez, L., Azam, T., McNamee, E. N., Clambey, E. T., et al. (2015) · Journal of Clinical Investigation

Hematopoietic Stem Cell TransplantationAcute Myeloid Leukemia Research

Cited by 148

A Polysaccharide Virulence Factor from Aspergillus fumigatus Elicits Anti-inflammatory Effects through Induction of Interleukin-1 Receptor Antagonist

Gresnigt, M. S., Bozza, S., Becker, K. L., Joosten, L. A. B., Abdollahi-Roodsaz, S., van der Berg, W. B., Dinarello, C. A., Netea, M. G., Fontaine, T., De Luca, A., et al. (2014) · PLoS Pathogens

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 142

Suppression of monosodium urate crystal-induced cytokine production by butyrate is mediated by the inhibition of class I histone deacetylases

Cleophas, M. C. P., Crişan, T. O., Lemmers, H., Toenhake-Dijkstra, H., Fossati, G., Jansen, T. L., Dinarello, C. A., Netea, M. G., & Joosten, L. A. B. (2016) · Annals of the Rheumatic Diseases

Gout, Hyperuricemia, Uric AcidInflammasome and immune disorders

Cited by 139

IL-1α Is a DNA Damage Sensor Linking Genotoxic Stress Signaling to Sterile Inflammation and Innate Immunity

Cohen, I., Rider, P., Vornov, E., Tomas, M., Tudor, C., Wegner, M., Brondani, L., Freudenberg, M., Mittler, G., Ferrando-May, E., et al. (2015) · Scientific Reports

DNA Repair MechanismsImmune Response and Inflammation

Cited by 98

Treating Life-Threatening Myocarditis by Blocking Interleukin-1*

Cavalli, G., Pappalardo, F., Mangieri, A., Dinarello, C. A., Dagna, L., & Tresoldi, M. (2016) · Critical Care Medicine

Viral Infections and Immunology ResearchMechanical Circulatory Support Devices

Cited by 96

Plasma Cytokines, Cytokine Antagonists, and Disease Progression in African Women Infected with HIV-1

Thea, D. M., Porat, R., Nagimbi, K., Baangi, M., St. Louis, M. E., Kaplan, G., Dinarello, C. A., & Keusch, G. T. (1996) · Annals of Internal Medicine

HIV Research and TreatmentHIV-related health complications and treatments

Cited by 81

Effect of interleukin-18 on mouse core body temperature

Gatti, S., Beck, J., Fantuzzi, G., Bartfai, T., & Dinarello, C. A. (2002) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Thermal Regulation in MedicineInflammasome and immune disorders

Cited by 72

Interleukin-1 Receptor Blockade Rescues Myocarditis-Associated End-Stage Heart Failure

Cavalli, G., Foppoli, M., Cabrini, L., Dinarello, C. A., Tresoldi, M., & Dagna, L. (2017) · Frontiers in Immunology

Viral Infections and Immunology ResearchCardiac Fibrosis and Remodeling

Cited by 70

Pro-inflammatory cytokine blockade attenuates myeloid expansion in a murine model of rheumatoid arthritis

Hernandez, G., Mills, T. S., Rabe, J. L., Chavez, J. S., Kuldanek, S., Kirkpatrick, G., Noetzli, L., Jubair, W. K., Zanche, M., Myers, J. R., et al. (2020) · Haematologica

Rheumatoid Arthritis Research and TherapiesHematopoietic Stem Cell Transplantation

Cited by 58

Treating Pulmonary Silicosis by Blocking Interleukin 1

Cavalli, G., Fallanca, F., Dinarello, C. A., & Dagna, L. (2015) · American Journal of Respiratory and Critical Care Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisOccupational and environmental lung diseases

Cited by 56