Dinarello, Charles A.

Neuroinflammation in Alzheimer's disease

Heneka, M. T., Carson, M. J., Khoury, J. E., Landreth, G. E., Brosseron, F., Feinstein, D. L., Jacobs, A. H., Wyss-Coray, T., Vitorica, J., Ransohoff, R. M., et al. (2015) · The Lancet Neurology

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 6,226

Immunological and inflammatory functions of the interleukin-1 family

Dinarello, C. A. (2009) · Annual Review of Immunology

Immune Response and InflammationInflammasome and immune disorders

Cited by 3,466

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

Dinarello, C. A. (2011) · Blood

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 2,248

The interleukin-1 family: back to the future

Garlanda, C., Dinarello, C. A., & Mantovani, A. (2013) · Immunity

IL-33, ST2, and ILC PathwaysImmune Response and Inflammation

Cited by 1,945

Overview of the IL ‐1 family in innate inflammation and acquired immunity

Dinarello, C. A. (2018) · Immunological Reviews

Immune Response and InflammationInflammasome and immune disorders

Cited by 1,866

Detection of circulating tumor necrosis factor after endotoxin administration

Michie, H. R., Manogue, K. R., Spriggs, D. R., Revhaug, A., O'Dwyer, S., Dinarello, C. A., Cerami, A., Wolff, S. M., & Wilmore, D. W. (1988) · New England Journal of Medicine

Immune Response and InflammationSepsis Diagnosis and Treatment

Cited by 1,677

Immunoregulatory Feedback Between Interleukin-1 and Glucocorticoid Hormones

Besedovsky, H., del Rey, A., Sorkin, E., & Dinarello, C. A. (1986) · Science

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 1,519

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.

Dinarello, C. A., Cannon, J. G., Wolff, S. M., Bernheim, H. A., Beutler, B., Cerami, A., Figari, I. S., Palladino, M. A., & O'Connor, J. V. (1986) · The Journal of experimental medicine

Immune Response and InflammationThermal Regulation in Medicine

Cited by 1,472

Anti-inflammatory Agents: Present and Future

Dinarello, C. A. (2010) · Cell

Inflammatory mediators and NSAID effectsNF-κB Signaling Pathways

Cited by 1,095

Interleukin-1 and Related Cytokines in the Regulation of Inflammation and Immunity

Mantovani, A., Dinarello, C. A., Molgora, M., & Garlanda, C. (2019) · Immunity

IL-33, ST2, and ILC PathwaysCytokine Signaling Pathways and Interactions

Cited by 1,046

Interleukin-18 and IL-18 Binding Protein

Dinarello, C. A., Novick, D., Kim, S., & Kaplanski, G. (2013) · Frontiers in Immunology

Cytokine Signaling Pathways and InteractionsInflammasome and immune disorders

Cited by 938

Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity

Arts, R. J. W., Novakovic, B., ter Horst, R., Carvalho, A., Bekkering, S., Lachmandas, E., Rodrigues, F., Silvestre, R., Cheng, S.-C., Wang, S.-Y., et al. (2016) · Cell Metabolism

Immune responses and vaccinationsImmune cells in cancer

Cited by 930

Historical insights into cytokines

Dinarello, C. A. (2007) · European Journal of Immunology

Cytokine Signaling Pathways and InteractionsImmune Response and Inflammation

Cited by 926

Cytokine-Induced Expression of HIV-1 in a Chronically Infected Promonocyte Cell Line

Folks, T. M., Justement, J., Kinter, A., Dinarello, C. A., & Fauci, A. S. (1987) · Science

HIV Research and TreatmentT-cell and Retrovirus Studies

Cited by 905

Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome: Reanalysis of a Prior Phase III Trial*

Shakoory, B., Carcillo, J. A., Chatham, W. W., Amdur, R. L., Zhao, H., Dinarello, C. A., Cron, R. Q., & Opal, S. M. (2016) · Critical Care Medicine

Sepsis Diagnosis and TreatmentAutoimmune and Inflammatory Disorders Research

Cited by 867

A guiding map for inflammation

Netea, M. G., Balkwill, F., Chonchol, M., Cominelli, F., Donath, M. Y., Giamarellos-Bourboulis, E. J., Golenbock, D., Gresnigt, M. S., Heneka, M. T., Hoffman, H. M., et al. (2017) · Nature Immunology

Immune Response and InflammationInflammation biomarkers and pathways

Cited by 831

The interleukin‐1 family: 10 years of discovery 1

Dinarello, C. A. (1994) · The FASEB Journal

Cytokine Signaling Pathways and InteractionsImmune Response and Inflammation

Cited by 783

Cachectin/TNF and IL-1 Induced by Glucose-Modified Proteins: Role in Normal Tissue Remodeling

Vlassara, H., Brownlee, M., Manogue, K. R., Dinarello, C. A., & Pasagian, A. (1988) · Science

Advanced Glycation End Products researchPhagocytosis and Immune Regulation

Cited by 597

IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation

Ben-Sasson, S. Z., Hu-Li, J., Quiel, J., Cauchetaux, S., Ratner, M., Shapira, I., Dinarello, C. A., & Paul, W. E. (2009) · Proceedings of the National Academy of Sciences

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 568

Inflammatory markers and the risk of Alzheimer disease: The Framingham Study

Tan, Z. S., Beiser, A. S., Vasan, R. S., Roubenoff, R., Dinarello, C. A., Harris, T. B., Benjamin, E. J., Au, R., Kiel, D. P., Wolf, P. A., et al. (2007) · Neurology

Dementia and Cognitive Impairment ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 440

Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance

Netea, M. G., Joosten, L. A. B., Lewis, E., Jensen, D. R., Voshol, P. J., Kullberg, B. J., Tack, C. J., van Krieken, H., Kim, S.-H., Stalenhoef, A. F., et al. (2006) · Nature Medicine

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 424

Monocyte Cytokine Production in an Elderly Population: Effect of Age and Inflammation

Roubenoff, R., Harris, T. B., Abad, L. W., Wilson, P. W. F., Dallal, G. E., & Dinarello, C. A. (1998) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Adipokines, Inflammation, and Metabolic DiseasesImmune Response and Inflammation

Cited by 418

Targeting innate immune mediators in type 1 and type 2 diabetes

Donath, M. Y., Dinarello, C. A., & Mandrup-Poulsen, T. (2019) · Nature Reviews Immunology

Adipokines, Inflammation, and Metabolic DiseasesPancreatic function and diabetes

Cited by 416

Receptor interacting protein kinase 2–mediated mitophagy regulates inflammasome activation during virus infection

Lupfer, C., Thomas, P. G., Anand, P. K., Vogel, P., Milasta, S., Martinez, J., Huang, G., Green, M., Kundu, M., Chi, H., et al. (2013) · Nature Immunology

Inflammasome and immune disordersAutophagy in Disease and Therapy

Cited by 384