Holmes, Andrew

Genetic Sensitivity to the Environment: The Case of the Serotonin Transporter Gene and Its Implications for Studying Complex Diseases and Traits

Caspi, A., Hariri, A. R., Holmes, A., Uher, R., & Moffitt, T. E. (2010) · American Journal of Psychiatry

Neurotransmitter Receptor Influence on BehaviorGenetic Associations and Epidemiology

Cited by 1,346

The ascent of mouse: advances in modelling human depression and anxiety

Cryan, J. F., & Holmes, A. (2005) · Nature Reviews Drug Discovery

Neurotransmitter Receptor Influence on BehaviorStress Responses and Cortisol

Cited by 1,198

Stress and Fear Extinction

Maren, S., & Holmes, A. (2016) · Neuropsychopharmacology

Memory and Neural MechanismsPosttraumatic Stress Disorder Research

Cited by 412

Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders

Singewald, N., Schmuckermair, C., Whittle, N., Holmes, A., & Ressler, K. J. (2015) · Pharmacology & Therapeutics

Memory and Neural MechanismsPosttraumatic Stress Disorder Research

Cited by 390

Impaired stress-coping and fear extinction and abnormal corticolimbic morphology in serotonin transporter knock-out mice

Wellman, C. L., Izquierdo, A., Garrett, J. E., Martin, K. P., Carroll, J., Millstein, R., Lesch, K.-P., Murphy, D. L., & Holmes, A. (2007) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorMemory and Neural Mechanisms

Cited by 366

Loss of GluN2B-Containing NMDA Receptors in CA1 Hippocampus and Cortex Impairs Long-Term Depression, Reduces Dendritic Spine Density, and Disrupts Learning

Brigman, J. L., Wright, T., Talani, G., Prasad-Mulcare, S., Jinde, S., Seabold, G. K., Mathur, P., Davis, M. I., Bock, R., Gustin, R. M., et al. (2010) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 339

Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity

Gunduz-Cinar, O., MacPherson, K. P., Cinar, R., Gamble-George, J., Sugden, K., Williams, B., Godlewski, G., Ramikie, T. S., Gorka, A. X., Alapafuja, S. O., et al. (2013) · Molecular Psychiatry

Cannabis and Cannabinoid ResearchMemory and Neural Mechanisms

Cited by 307

New translational assays for preclinical modelling of cognition in schizophrenia: The touchscreen testing method for mice and rats

Bussey, T. J., Holmes, A., Lyon, L., Mar, A. C., McAllister, K. A. L., Nithianantharajah, J., Oomen, C. A., & Saksida, L. M. (2012) · Neuropharmacology

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 299

Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease

Holmes, A. (2008) · Neuroscience & Biobehavioral Reviews

Neurotransmitter Receptor Influence on BehaviorStress Responses and Cortisol

Cited by 264

Prefrontal inputs to the amygdala instruct fear extinction memory formation

Bukalo, O., Pinard, C. R., Silverstein, S., Brehm, C., Hartley, N. D., Whittle, N., Colacicco, G., Busch, E., Patel, S., Singewald, N., et al. (2015) · Science Advances

Memory and Neural MechanismsMemory Processes and Influences

Cited by 234

Fear extinction requires infralimbic cortex projections to the basolateral amygdala

Bloodgood, D. W., Sugam, J. A., Holmes, A., & Kash, T. L. (2018) · Translational Psychiatry

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 229

Strain Differences in Stress Responsivity Are Associated with Divergent Amygdala Gene Expression and Glutamate-Mediated Neuronal Excitability

Mozhui, K., Karlsson, R.-M., Kash, T. L., Ihne, J., Norcross, M., Patel, S., Farrell, M. R., Hill, E. E., Graybeal, C., Martin, K. P., et al. (2010) · The Journal of Neuroscience

Stress Responses and CortisolNeuroscience and Neuropharmacology Research

Cited by 226

Chronic alcohol remodels prefrontal neurons and disrupts NMDAR-mediated fear extinction encoding

Holmes, A., Fitzgerald, P. J., MacPherson, K. P., DeBrouse, L., Colacicco, G., Flynn, S. M., Masneuf, S., Pleil, K. E., Li, C., Marcinkiewcz, C. A., et al. (2012) · Nature Neuroscience

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 218

Galanin GAL-R1 Receptor Null Mutant Mice Display Increased Anxiety-Like Behavior Specific to the Elevated Plus-Maze

Holmes, A., Kinney, J. W., Wrenn, C. C., Li, Q., Yang, R. J., Ma, L., Vishwanath, J., Saavedra, M. C., Innerfield, C. E., Jacoby, A. S., et al. (2003) · Neuropsychopharmacology

Neuropeptides and Animal PhysiologyNeuroendocrine regulation and behavior

Cited by 202

Glutamatergic targets for new alcohol medications

Holmes, A., Spanagel, R., & Krystal, J. H. (2013) · Psychopharmacology

Neuroscience and Neuropharmacology ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 197

Amygdala Circuit Substrates for Stress Adaptation and Adversity

Zhang, W.-H., Zhang, J.-Y., Holmes, A., & Pan, B.-X. (2021) · Biological Psychiatry

Stress Responses and CortisolMemory and Neural Mechanisms

Cited by 196

Pharmacological or genetic inactivation of the serotonin transporter improves reversal learning in mice

Brigman, J. L., Mathur, P., Harvey-White, J., Izquierdo, A., Saksida, L. M., Bussey, T. J., Fox, S., Deneris, E., Murphy, D. L., & Holmes, A. (2010) · Cerebral Cortex

Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology Studies

Cited by 184

Chronic Stress Remodels Synapses in an Amygdala Circuit-Specific Manner

Zhang, J.-Y., Liu, T.-H., He, Y., Pan, H.-Q., Zhang, W.-H., Yin, X.-P., Tian, X.-L., Li, B.-M., Wang, X.-D., Holmes, A., et al. (2019) · Biological Psychiatry

Neuroscience and Neuropharmacology ResearchStress Responses and Cortisol

Cited by 183

Assessment of Glutamate Transporter GLAST (EAAT1)-Deficient Mice for Phenotypes Relevant to the Negative and Executive/Cognitive Symptoms of Schizophrenia

Karlsson, R.-M., Tanaka, K., Saksida, L. M., Bussey, T. J., Heilig, M., & Holmes, A. (2009) · Neuropsychopharmacology

Schizophrenia research and treatmentNeuroscience and Neuropharmacology Research

Cited by 165

Chronic stress dysregulates amygdalar output to the prefrontal cortex

Lowery-Gionta, E. G., Crowley, N. A., Bukalo, O., Silverstein, S., Holmes, A., & Kash, T. L. (2018) · Neuropharmacology

Stress Responses and CortisolNeuroscience and Neuropharmacology Research

Cited by 84

Enhanced Extinction of Aversive Memories by High-Frequency Stimulation of the Rat Infralimbic Cortex

Maroun, M., Kavushansky, A., Holmes, A., Wellman, C., & Motanis, H. (2012) · PLoS ONE

Memory and Neural MechanismsTranscranial Magnetic Stimulation Studies

Cited by 79

Reduced alcohol intake and reward associated with impaired endocannabinoid signaling in mice with a deletion of the glutamate transporter GLAST

Karlsson, R.-M., Adermark, L., Molander, A., Perreau-Lenz, S., Singley, E., Solomon, M., Holmes, A., Tanaka, K., Lovinger, D. M., Spanagel, R., et al. (2012) · Neuropharmacology

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 44

Genome-wide association for testis weight in the diversity outbred mouse population

Yuan, J. T., Gatti, D. M., Philip, V. M., Kasparek, S., Kreuzman, A. M., Mansky, B., Sharif, K., Taterra, D., Taylor, W. M., Thomas, M., et al. (2018) · Mammalian Genome

Genetic Mapping and Diversity in Plants and AnimalsGenetic and phenotypic traits in livestock

Cited by 15