Kieffer, Brigitte L.
Douglas Mental Health University Institute · McGill University
15 papers on CoChatORCID 0000-0002-8809-8334
Most cited papers
- Verified
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the μ-opioid-receptor gene
Matthes, H. W. D., Maldonado, R., Simonin, F., Valverde, O., Slowe, S., Kitchen, I., Befort, K., Dierich, A., Le Meur, M., Dollé, P., et al. (1996) · Nature
Neuropeptides and Animal PhysiologyNeurotransmitter Receptor Influence on Behavior
Cited by 1,722
- Verified
Reward Processing by the Opioid System in the Brain
Le Merrer, J., Becker, J. A. J., Befort, K., & Kieffer, B. L. (2009) · Physiological Reviews
Neuropeptides and Animal PhysiologyNeurotransmitter Receptor Influence on Behavior
Cited by 1,013
- Verified
Mice deficient for δ- and μ-opioid receptors exhibit opposing alterations of emotional responses
Filliol, D., Ghozland, S., Chluba, J., Martin, M., Matthes, H. W. D., Simonin, F., Befort, K., Gavériaux-Ruff, C., Dierich, A., LeMeur, M., et al. (2000) · Nature Genetics
Neuropeptides and Animal PhysiologyNeurotransmitter Receptor Influence on Behavior
Cited by 672
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Exploring the opioid system by gene knockout
Kieffer, B. L., & Gavériaux-Ruff, C. (2002) · Progress in Neurobiology
Neuropeptides and Animal PhysiologyNeurotransmitter Receptor Influence on Behavior
Cited by 620
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Opioid receptors: Distinct roles in mood disorders
Lutz, P.-E., & Kieffer, B. L. (2013) · Trends in Neurosciences
Neuropeptides and Animal PhysiologyNeurotransmitter Receptor Influence on Behavior
Cited by 542
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Deficit in Attachment Behavior in Mice Lacking the µ-Opioid Receptor Gene
Moles, A., Kieffer, B. L., & D'Amato, F. R. (2004) · Science
Neuroendocrine regulation and behaviorNeuropeptides and Animal Physiology
Cited by 449
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Disruption of the κ‐opioid receptor gene in mice enhances sensitivity to chemical visceral pain, impairs pharmacological actions of the selective κ‐agonist U‐50,488H and attenuates morphine withdrawal
Simonin, F., Valverde, O., Smadja, C., Slowe, S., Kitchen, I., Dierich, A., Le Meur, M., Roques, B. P., Maldonado, R., & Kieffer, B. L. (1998) · The EMBO Journal
Neuropeptides and Animal PhysiologyPain Mechanisms and Treatments
Cited by 418
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Buprenorphine-Induced Antinociception Is Mediated by μ-Opioid Receptors and Compromised by Concomitant Activation of Opioid Receptor-Like Receptors
Lutfy, K., Eitan, S., Bryant, C. D., Yang, Y. C., Saliminejad, N., Walwyn, W., Kieffer, B. L., Takeshima, H., Carroll, F. I., Maidment, N. T., et al. (2003) · The Journal of Neuroscience
Neuropeptides and Animal PhysiologyPain Mechanisms and Treatments
Cited by 211
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Translating the habenula-from rodents to humans
Boulos, L.-J., Darcq, E., & Kieffer, B. L. (2017) · Biological Psychiatry
Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology Studies
Cited by 164
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Impaired Emotional-Like Behavior and Serotonergic Function During Protracted Abstinence from Chronic Morphine
Goeldner, C., Lutz, P.-E., Darcq, E., Halter, T., Clesse, D., Ouagazzal, A.-M., & Kieffer, B. L. (2011) · Biological Psychiatry
Neurotransmitter Receptor Influence on BehaviorNeuropeptides and Animal Physiology
Cited by 163
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Deletion of the mu opioid receptor gene in mice reshapes the reward-aversion connectome
Mechling, A. E., Arefin, T., Lee, H.-L., Bienert, T., Reisert, M., Ben Hamida, S., Darcq, E., Ehrlich, A., Gaveriaux-Ruff, C., Parent, M. J., et al. (2016) · Proceedings of the National Academy of Sciences
Functional Brain Connectivity StudiesNeurotransmitter Receptor Influence on Behavior
Cited by 80
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Differential behavioral and molecular alterations upon protracted abstinence from cocaine versus morphine, nicotine, THC and alcohol: Abstinence across drugs
Becker, J. A. J., Kieffer, B. L., & Le Merrer, J. (2017) · Addiction Biology
Neurotransmitter Receptor Influence on BehaviorSubstance Abuse Treatment and Outcomes
Cited by 77
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Interacting Cannabinoid and Opioid Receptors in the Nucleus Accumbens Core Control Adolescent Social Play
Manduca, A., Lassalle, O., Sepers, M., Campolongo, P., Cuomo, V., Marsicano, G., Kieffer, B., Vanderschuren, L. J. M. J., Trezza, V., & Manzoni, O. J. J. (2016) · Frontiers in Behavioral Neuroscience
Cannabis and Cannabinoid ResearchNeurotransmitter Receptor Influence on Behavior
Cited by 73
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Cholecystokinin knock-down in the basolateral amygdala has anxiolytic and antidepressant-like effects in mice
Del Boca, C., Lutz, P. E., Le Merrer, J., Koebel, P., & Kieffer, B. L. (2012) · Neuroscience
Neuropeptides and Animal PhysiologyNeurotransmitter Receptor Influence on Behavior
Cited by 59
- Verified
Focusing on the Opioid System for Addiction Biomarker Discovery
Belzeaux, R., Lalanne, L., Kieffer, B. L., & Lutz, P.-E. (2018) · Trends in Molecular Medicine
Neuropeptides and Animal PhysiologyOpioid Use Disorder Treatment
Cited by 28
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