Fleishman, Sarel J.

Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin

Fleishman, S. J., Whitehead, T. A., Ekiert, D. C., Dreyfus, C., Corn, J. E., Strauch, E.-M., Wilson, I. A., & Baker, D. (2011) · Science

Protein Structure and DynamicsInfluenza Virus Research Studies

Cited by 585

High-resolution mapping of protein sequence-function relationships

Fowler, D. M., Araya, C. L., Fleishman, S. J., Kellogg, E. H., Stephany, J. J., Baker, D., & Fields, S. (2010) · Nature Methods

Chemical Synthesis and AnalysisProtein Structure and Dynamics

Cited by 516

Principles for computational design of binding antibodies

Baran, D., Pszolla, M. G., Lapidoth, G. D., Norn, C., Dym, O., Unger, T., Albeck, S., Tyka, M. D., & Fleishman, S. J. (2017) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsMonoclonal and Polyclonal Antibodies Research

Cited by 136

AbDesign: An algorithm for combinatorial backbone design guided by natural conformations and sequences: Combinatorial Backbone Design in Antibodies

Lapidoth, G. D., Baran, D., Pszolla, G. M., Norn, C., Alon, A., Tyka, M. D., & Fleishman, S. J. (2015) · Proteins Structure Function and Bioinformatics

Protein Structure and DynamicsMonoclonal and Polyclonal Antibodies Research

Cited by 107

Combinatorial assembly and design of enzymes

Lipsh-Sokolik, R., Khersonsky, O., Schröder, S. P., de Boer, C., Hoch, S.-Y., Davies, G. J., Overkleeft, H. S., & Fleishman, S. J. (2023) · Science

Protein Structure and DynamicsEnzyme Catalysis and Immobilization

Cited by 78

Protein quaternary structures in solution are a mixture of multiple forms

Marciano, S., Dey, D., Listov, D., Fleishman, S. J., Sonn-Segev, A., Mertens, H., Busch, F., Kim, Y., Harvey, S. R., Wysocki, V. H., et al. (2022) · Chemical Science

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 41

Preclinical Development of a Stabilized RH5 Virus-Like Particle Vaccine that Induces Improved Anti-Malarial Antibodies

King, L. D. W., Pulido, D., Barrett, J. R., Davies, H., Quinkert, D., Lias, A. M., Silk, S. E., Pattinson, D. J., Diouf, A., Williams, B. G., et al. (2024) · Cell Reports Medicine

Malaria Research and ControlImmunotherapy and Immune Responses

Cited by 27

Preclinical development of a stabilized RH5 virus-like particle vaccine that induces improved antimalarial antibodies

King, L. D. W., Pulido, D., Barrett, J. R., Davies, H., Quinkert, D., Lias, A. M., Silk, S. E., Pattinson, D. J., Diouf, A., Williams, B. G., et al. (2024) · Cell Reports Medicine

Malaria Research and ControlImmunotherapy and Immune Responses

Cited by 27

Assessing and enhancing foldability in designed proteins

Listov, D., Lipsh‐Sokolik, R., Rosset, S., Yang, C., Correia, B. E., & Fleishman, S. J. (2022) · Protein Science

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 24

The C-terminal tail of CSNAP attenuates the CSN complex

Füzesi-Levi, M. G., Ben-Nissan, G., Listov, D., Fridmann Sirkis, Y., Hayouka, Z., Fleishman, S., & Sharon, M. (2023) · Life Science Alliance

Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors

Cited by 5

The C-terminal tail of CSNAP attenuates the CSN complex

Füzesi-Levi, M. G., Ben-Nissan, G., Listov, D., Hayouka, Z., Fleishman, S., & Sharon, M. (2022) · Life Science Alliance

Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors

Cited by 5

Protein Quaternary Structures in Solution are a Mixture of Multiple forms

Marciano, S., Dey, D., Listov, D., Fleishman, S. J., Sonn-Segev, A., Mertens, H., Busch, F., Kim, Y., Harvey, S. R., Wysocki, V. H., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory)

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 3

Optimizing stability in dynamic small-molecule binding proteins

Scherer, M., Kriegel, M., Höcker, B., & Fleishman, S. J. (2025) · Journal of the American Chemical Society

Protein Structure and DynamicsBiochemical and Structural Characterization

Cited by 2

Optimizing Stability in Dynamic Small-Molecule Binding Proteins

Scherer, M., Kriegel, M., Höcker, B., & Fleishman, S. J. (2026) · Journal of the American Chemical Society

Protein Structure and DynamicsBiochemical and Structural Characterization

Cited by 2

Combinatorial assembly and design of enzymes

Lipsh-Sokolik, R., Khersonsky, O., Schröder, S. P., de Boer, C., Hoch, S.-Y., Davies, G. J., Overkleeft, H. S., & Fleishman, S. J. (2022) · bioRxiv (Cold Spring Harbor Laboratory)

Protein Structure and DynamicsEnzyme Catalysis and Immobilization

Cited by 2