Hanaoka, Fumio

The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η

Masutani, C., Kusumoto, R., Yamada, A., Dohmae, N., Yokoi, M., Yuasa, M., Araki, M., Iwai, S., Takio, K., & Hanaoka, F. (1999) · Nature

DNA Repair MechanismsGenetic factors in colorectal cancer

Cited by 1,292

Xeroderma Pigmentosum Group C Protein Complex Is the Initiator of Global Genome Nucleotide Excision Repair

Sugasawa, K., Ng, J. M. Y., Masutani, C., Iwai, S., van der Spek, P. J., Eker, A. P. M., Hanaoka, F., Bootsma, D., & Hoeijmakers, J. H. J. (1998) · Molecular Cell

DNA Repair MechanismsNuclear Structure and Function

Cited by 899

UV-Induced Ubiquitylation of XPC Protein Mediated by UV-DDB-Ubiquitin Ligase Complex

Sugasawa, K., Okuda, Y., Saijo, M., Nishi, R., Matsuda, N., Chu, G., Mori, T., Iwai, S., Tanaka, K., Tanaka, K., et al. (2005) · Cell

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 576

Mechanisms of accurate translesion synthesis by human DNA polymerase η

Masutani, C., Kusumoto, R., Iwai, S., & Hanaoka, F. (2000) · The EMBO Journal

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 504

The Molecular Basis of CRL4DDB2/CSA Ubiquitin Ligase Architecture, Targeting, and Activation

Fischer, E. S., Scrima, A., Böhm, K., Matsumoto, S., Lingaraju, G. M., Faty, M., Yasuda, T., Cavadini, S., Wakasugi, M., Hanaoka, F., et al. (2011) · Cell

Ubiquitin and proteasome pathwaysDNA Repair Mechanisms

Cited by 460

The comings and goings of nucleotide excision repair factors on damaged DNA

Riedl, T., Hanaoka, F., & Egly, J. (2003) · The EMBO Journal

DNA Repair MechanismsNuclear Structure and Function

Cited by 439

A multistep damage recognition mechanism for global genomic nucleotide excision repair

Sugasawa, K., Okamoto, T., Shimizu, Y., Masutani, C., Iwai, S., & Hanaoka, F. (2001) · Genes & Development

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 435

Low fidelity DNA synthesis by human DNA polymerase-η

Matsuda, T., Bebenek, K., Masutani, C., Hanaoka, F., & Kunkel, T. A. (2000) · Nature

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 372

Preferential cis–syn thymine dimer bypass by DNA polymerase η occurs with biased fidelity

McCulloch, S. D., Kokoska, R. J., Masutani, C., Iwai, S., Hanaoka, F., & Kunkel, T. A. (2004) · Nature

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 246

Two-step recognition of DNA damage for mammalian nucleotide excision repair: Directional binding of the XPC complex and DNA strand scanning

Sugasawa, K., Akagi, J.-I., Nishi, R., Iwai, S., & Hanaoka, F. (2009) · Molecular Cell

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 205

DNA Repair Protein XPA Binds Replication Protein A (RPA)

Matsuda, T., Saijo, M., Kuraoka, I., Kobayashi, T., Nakatsu, Y., Nagai, A., Enjoji, T., Masutani, C., Sugasawa, K., Hanaoka, F., et al. (1995) · Journal of Biological Chemistry

DNA Repair MechanismsNuclear Structure and Function

Cited by 174

Error rate and specificity of human and murine DNA polymerase η

Matsuda, T., Bebenek, K., Masutani, C., Rogozin, I. B., Hanaoka, F., & Kunkel, T. A. (2001) · Journal of Molecular Biology

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 170

HHR23B, a Human Rad23 Homolog, Stimulates XPC Protein in Nucleotide Excision Repair In Vitro

Sugasawa, K., Masutani, C., Uchida, A., Maekawa, T., Spek, P. J. V. D., Bootsma, D., Hoeijmakers, J. H. J., & Hanaoka, F. (1996) · Molecular and Cellular Biology

DNA Repair MechanismsNuclear Structure and Function

Cited by 164

Correlation of somatic hypermutation specificity and A-T base pair substitution errors by DNA polymerase η during copying of a mouse immunoglobulin κ light chain transgene

Pavlov, Y. I., Rogozin, I. B., Galkin, A. P., Aksenova, A. Y., Hanaoka, F., Rada, C., & Kunkel, T. A. (2002) · Proceedings of the National Academy of Sciences

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 120

In situ visualization of ultraviolet-light-induced DNA damage repair in locally irradiated human fibroblasts

Katsumi, S., Kobayashi, N., Imoto, K., Nakagawa, A., Yamashina, Y., Muramatsu, T., Shirai, T., Miyagawa, S., Sugiura, S., Hanaoka, F., et al. (2001) · Journal of Investigative Dermatology

DNA Repair MechanismsNuclear Structure and Function

Cited by 119

The XPC-HR23B complex displays high affinity and specificity for damaged DNA in a true-equilibrium fluorescence assay

Hey, T., Lipps, G., Sugasawa, K., Iwai, S., Hanaoka, F., & Krauss, G. (2002) · Biochemistry

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 114

Identification and Characterization of XPC-Binding Domain of hHR23B

Masutani, C., Araki, M., Sugasawa, K., van der Spek, P. J., Yamada, A., Uchida, A., Maekawa, T., Bootsma, D., Hoeijmakers, J. H. J., & Hanaoka, F. (1997) · Molecular and Cellular Biology

DNA Repair MechanismsNuclear Structure and Function

Cited by 100

UV-DDB-dependent regulation of nucleotide excision repair kinetics in living cells

Nishi, R., Alekseev, S., Dinant, C., Hoogstraten, D., Houtsmuller, A. B., Hoeijmakers, J. H. J., Vermeulen, W., Hanaoka, F., & Sugasawa, K. (2009) · DNA Repair

DNA Repair MechanismsNuclear Structure and Function

Cited by 76

Proofreading of DNA Polymerase η-dependent Replication Errors

Bebenek, K., Matsuda, T., Masutani, C., Hanaoka, F., & Kunkel, T. A. (2001) · Journal of Biological Chemistry

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 76

USP7 is a suppressor of PCNA ubiquitination and oxidative-stress-induced mutagenesis in human cells.

Kashiwaba, S.-I., Kanao, R., Masuda, Y., Kusumoto-Matsuo, R., Hanaoka, F., & Masutani, C. (2015) · Cell Reports

Ubiquitin and proteasome pathwaysDNA Repair Mechanisms

Cited by 71

Genomic structure, chromosomal localization and identification of mutations in the xeroderma pigmentosum variant (XPV) gene

Yuasa, M., Masutani, C., Eki, T., & Hanaoka, F. (2000) · Oncogene

DNA Repair MechanismsGenetic factors in colorectal cancer

Cited by 61

Exploration of ‘over kill effect’ of high-LET Ar- and Fe-ions by evaluating the fraction of non-hit cell and interphase death

MEHNATI, P., MORIMOTO, S., YATAGAI, F., FURUSAWA, Y., KOBAYASHI, Y., WADA, S., KANAI, T., HANAOKA, F., & SASAKI, H. (2005) · Journal of Radiation Research

Radiation Therapy and DosimetryEffects of Radiation Exposure

Cited by 40