Perkins, Guy

NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria

Zhong, Z., Umemura, A., Sanchez-Lopez, E., Liang, S., Shalapour, S., Wong, J., He, F., Boassa, D., Perkins, G., Ali, S. R., et al. (2016) · Cell

Inflammasome and immune disordersNF-κB Signaling Pathways

Cited by 1,197

Mitochondrial fragmentation in neurodegeneration.

Knott, A. B., Perkins, G., Schwarzenbacher, R., & Bossy-Wetzel, E. (2008) · Nature Reviews Neuroscience

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 1,002

Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies

Lee, J. H., Budanov, A. V., Park, E. J., Birse, R., Kim, T. E., Perkins, G. A., Ocorr, K., Ellisman, M. H., Bodmer, R., Bier, E., et al. (2010) · Science

Genetics, Aging, and Longevity in Model OrganismsPI3K/AKT/mTOR signaling in cancer

Cited by 570

Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3

Lee, J. H., Budanov, A. V., Talukdar, S., Park, E. J., Park, H. L., Park, H.-W., Bandyopadhyay, G., Li, N., Aghajan, M., Jang, I., et al. (2012) · Cell Metabolism

Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer

Cited by 295

Cerium oxide nanoparticles protect against Aβ-induced mitochondrial fragmentation and neuronal cell death

Dowding, J. M., Song, W., Bossy, K., Karakoti, A., Kumar, A., Kim, A., Bossy, B., Seal, S., Ellisman, M. H., Perkins, G., et al. (2014) · Cell Death & Differentiation

Mitochondrial Function and PathologyAlzheimer's disease research and treatments

Cited by 221

(–)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle

Nogueira, L., Ramirez‐Sanchez, I., Perkins, G. A., Murphy, A., Taub, P. R., Ceballos, G., Villarreal, F. J., Hogan, M. C., & Malek, M. H. (2011) · The Journal of Physiology

Exercise and Physiological ResponsesCardiovascular and exercise physiology

Cited by 205

The Fractalkine/CX3CR1 System Regulates β Cell Function and Insulin Secretion

Lee, Y. S., Morinaga, H., Kim, J. J., Lagakos, W., Taylor, S., Keshwani, M., Perkins, G., Dong, H., Kayali, A. G., Sweet, I. R., et al. (2013) · Cell

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 141

Alterations in skeletal muscle indicators of mitochondrial structure and biogenesis in patients with type 2 diabetes and heart failure: effects of epicatechin rich cocoa

Taub, P. R., Ramirez‐Sanchez, I., Ciaraldi, T. P., Perkins, G., Murphy, A. N., Naviaux, R., Hogan, M., Maisel, A. S., Henry, R. R., Ceballos, G., et al. (2012) · Clinical and Translational Science

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 122

Impact of chromogranin a deficiency on catecholamine storage, catecholamine granule morphology and chromaffin cell energy metabolism in vivo

Pasqua, T., Mahata, S., Bandyopadhyay, G. K., Biswas, A., Perkins, G. A., Sinha-Hikim, A. P., Goldstein, D. S., Eiden, L. E., & Mahata, S. K. (2016) · Cell and Tissue Research

Cellular transport and secretionPancreatic function and diabetes

Cited by 53