Ozato, Keiko

Immunodeficiency and Chronic Myelogenous Leukemia-like Syndrome in Mice with a Targeted Mutation of the ICSBP Gene

Holtschke, T., Löhler, J., Kanno, Y., Fehr, T., Giese, N., Rosenbauer, F., Lou, J., Knobeloch, K.-P., Gabriele, L., Waring, J. F., et al. (1996) · Cell

interferon and immune responsesImmunodeficiency and Autoimmune Disorders

Cited by 644

An interferon gamma-regulated protein that binds the interferon-inducible enhancer element of major histocompatibility complex class I genes.

Driggers, P. H., Ennist, D. L., Gleason, S. L., Mak, W. H., Marks, M. S., Levi, B. Z., Flanagan, J. R., Appella, E., & Ozato, K. (1990) · Proceedings of the National Academy of Sciences

interferon and immune responsesCytokine Signaling Pathways and Interactions

Cited by 356

IRF8 Is a Critical Transcription Factor for Transforming Microglia into a Reactive Phenotype

Masuda, T., Tsuda, M., Yoshinaga, R., Tozaki-Saitoh, H., Ozato, K., Tamura, T., & Inoue, K. (2012) · Cell Reports

Neuroinflammation and Neurodegeneration MechanismsPain Mechanisms and Treatments

Cited by 338

Neurophysin in the hypothalamo-neurohypophysial system. I. Production and characterization of monoclonal antibodies

Ben-Barak, Y., Russell, J., Whitnall, M., Ozato, K., & Gainer, H. (1985) · The Journal of Neuroscience

Neuroendocrine regulation and behaviorNeuropeptides and Animal Physiology

Cited by 313

Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation

Kurotaki, D., Osato, N., Nishiyama, A., Yamamoto, M., Ban, T., Sato, H., Nakabayashi, J., Umehara, M., Miyake, N., Matsumoto, N., et al. (2013) · Blood

Genomics and Chromatin DynamicsKruppel-like factors research

Cited by 252

Interferon Consensus Sequence Binding Protein–deficient Mice Display Impaired Resistance to Intracellular Infection Due to a Primary Defect in Interleukin 12 p40 Induction

Scharton-Kersten, T., Contursi, C., Masumi, A., Sher, A., & Ozato, K. (1997) · The Journal of Experimental Medicine

Toxoplasma gondii Research StudiesImmune Response and Inflammation

Cited by 217

Neurophysin in the hypothalamo-neurohypophysial system. II. Immunocytochemical studies of the ontogeny of oxytocinergic and vasopressinergic neurons

Whitnall, M., Key, S., Ben-Barak, Y., Ozato, K., & Gainer, H. (1985) · The Journal of Neuroscience

Neuroendocrine regulation and behaviorNeuropeptides and Animal Physiology

Cited by 209

Induction of MHC Class I Expression by the MHC Class II Transactivator CIITA

Martin, B. K., Chin, K.-C., Olsen, J. C., Skinner, C. A., Dey, A., Ozato, K., & Ting, J. P.-Y. (1997) · Immunity

Genomics and Chromatin DynamicsImmunotherapy and Immune Responses

Cited by 208

Interferon Consensus sequence-Binding Protein, a Member of the Interferon Regulatory Factor Family, Suppresses Interferon-Induced Gene Transcription

Nelson, N., Marks, M. S., Driggers, P. H., & Ozato, K. (1993) · Molecular and Cellular Biology

interferon and immune responsesCytokine Signaling Pathways and Interactions

Cited by 192

Interferon consensus sequence-binding protein, a member of the interferon regulatory factor family, suppresses interferon-induced gene transcription.

Nelson, N., Marks, M. S., Driggers, P. H., & Ozato, K. (1993) · Molecular and Cellular Biology

interferon and immune responsesCytokine Signaling Pathways and Interactions

Cited by 192

An IFN-γ-Inducible Transcription Factor, IFN Consensus Sequence Binding Protein (ICSBP), Stimulates IL-12 p40 Expression in Macrophages

Wang, I.-M., Contursi, C., Masumi, A., Ma, X., Trinchieri, G., & Ozato, K. (2000) · The Journal of Immunology

interferon and immune responsesCytokine Signaling Pathways and Interactions

Cited by 187

IRF family proteins and type I interferon induction in dendritic cells

Tailor, P., Tamura, T., & Ozato, K. (2006) · Cell Research

interferon and immune responsesImmune Response and Inflammation

Cited by 186

Review: ICSBP/IRF-8: Its Regulatory Roles in the Development of Myeloid Cells

Tamura, T., & Ozato, K. (2002) · Journal of Interferon & Cytokine Research

interferon and immune responsesAcute Myeloid Leukemia Research

Cited by 183

The genomic structure of the murine ICSBP gene reveals the presence of the gamma interferon-responsive element, to which an ISGF3 alpha subunit (or similar) molecule binds.

Kanno, Y., Kozak, C. A., Schindler, C., Driggers, P. H., Ennist, D. L., Gleason, S. L., Darnell, J. E., & Ozato, K. (1993) · Molecular and Cellular Biology

interferon and immune responsesCytokine Signaling Pathways and Interactions

Cited by 180

Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction

Konishi, H., Okamoto, T., Hara, Y., Komine, O., Tamada, H., Maeda, M., Osako, F., Kobayashi, M., Nishiyama, A., Kataoka, Y., et al. (2020) · The EMBO Journal

Neuroinflammation and Neurodegeneration MechanismsPhagocytosis and Immune Regulation

Cited by 179

Phosphorylation Events Modulate the Ability of Interferon Consensus Sequence Binding Protein to Interact with Interferon Regulatory Factors and to Bind DNA

Sharf, R., Meraro, D., Azriel, A., Thornton, A. M., Ozato, K., Petricoin, E. F., Larner, A. C., Schaper, F., Hauser, H., & Levi, B.-Z. (1997) · Journal of Biological Chemistry

interferon and immune responsesCytokine Signaling Pathways and Interactions

Cited by 162

Human interferon consensus sequence binding protein is a negative regulator of enhancer elements common to interferon-inducible genes.

Weisz, A., Marx, P., Sharf, R., Appella, E., Driggers, P. H., Ozato, K., & Levi, B. Z. (1992) · Journal of Biological Chemistry

interferon and immune responsesGenomics and Chromatin Dynamics

Cited by 152

Inhibition of p300 Histone Acetyltransferase by Viral Interferon Regulatory Factor

Li, M., Damania, B., Alvarez, X., Ogryzko, V., Ozato, K., & Jung, J. U. (2000) · Molecular and Cellular Biology

Viral-associated cancers and disordersGenomics and Chromatin Dynamics

Cited by 142

Immune cell-specific amplification of interferon signaling by the IRF-4/8-PU. 1 complex

Kanno, Y., Levi, B.-Z., Tamura, T., & Ozato, K. (2005) · Journal of Interferon & Cytokine Research

interferon and immune responsesCytokine Signaling Pathways and Interactions

Cited by 128

The Histone Acetylase PCAF Is a Phorbol-Ester-Inducible Coactivator of the IRF Family That Confers Enhanced Interferon Responsiveness

Masumi, A., Wang, I.-M., Lefebvre, B., Yang, X.-J., Nakatani, Y., & Ozato, K. (1999) · Molecular and Cellular Biology

interferon and immune responsesGenomics and Chromatin Dynamics

Cited by 124

Regulation of Apoptosis in Myeloid Cells by Interferon Consensus Sequence–Binding Protein

Gabriele, L., Phung, J., Fukumoto, J., Segal, D., Wang, I.-M., Giannakakou, P., Giese, N. A., Ozato, K., & Morse, H. C. (1999) · The Journal of Experimental Medicine

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 114

Expression of IFN regulatory factor family proteins in lymphocytes. Induction of Stat-1 and IFN consensus sequence binding protein expression by T cell activation

Nelson, N., Kanno, Y., Hong, C., Contursi, C., Fujita, T., Fowlkes, B. J., O’Connell, E., Hu-Li, J., Paul, W. E., Jankovic, D., et al. (1996) · The Journal of Immunology

interferon and immune responsesCytokine Signaling Pathways and Interactions

Cited by 110

Transcription factors that regulate growth and differentiation of myeloid cells.

Nagamura-Inoue, T., Tamura, T., & Ozato, K. (2001) · International Reviews of Immunology

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 94

IFN consensus sequence binding protein potentiates STAT1-dependent activation of IFNγ-responsive promoters in macrophages

Contursi, C., Wang, I.-M., Gabriele, L., Gadina, M., O'Shea, J., Morse, H. C., & Ozato, K. (2000) · Proceedings of the National Academy of Sciences

Cytokine Signaling Pathways and Interactionsinterferon and immune responses

Cited by 72