Interferon Consensus sequence-Binding Protein, a Member of the Interferon Regulatory Factor Family, Suppresses Interferon-Induced Gene Transcription

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Chomczynski, P., & Sacchi, N. (1987) · Analytical Biochemistry · doi:10.1006/abio.1987.9999 · Cited by 65,240 · see citing works

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

Chomczyński, P., & Sacchi, N. (1987) · Analytical Biochemistry · doi:10.1016/0003-2697(87)90021-2 · Cited by 47,092 · see citing works

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

Feinberg, A. P., & Vogelstein, B. (1983) · Analytical Biochemistry · doi:10.1016/0003-2697(83)90418-9 · Cited by 24,512 · see citing works

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

Saiki, R. K., Gelfand, D. H., Stoffel, S., Scharf, S. J., Higuchi, R., Horn, G. T., Mullis, K. B., & Erlich, H. A. (1988) · Science · doi:10.1126/science.2448875 · Cited by 17,719 · see citing works

Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity.

Nathan, C. F., Murray, H. W., Wiebe, M. E., & Rubin, B. Y. (1983) · The Journal of experimental medicine · doi:10.1084/jem.158.3.670 · Cited by 1,962 · see citing works

INTERFERONS AND THEIR ACTIONS

Pestka, S., Langer, J. A., Zoon, K. C., & Samuel, C. E. (1987) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.56.070187.003455 · Cited by 1,826 · see citing works

Lymphokine Control of In Vivo Immunoglobulin Isotype Selection

Finkelman, F. D., Holmes, J. M., Katona, I. M., Urban, J. F., Beckmann, M. P., Park, L. S., Schooley, K., Coffman, R. L., Mosmann, T. R., & Paul, W. E. (1990) · Annual Review of Immunology · doi:10.1146/annurev.iy.08.040190.001511 · Cited by 1,301 · see citing works

The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection.

Gorman, C. M., Merlino, G. T., Willingham, M. C., Pastan, I. H., & Howard, B. H. (1982) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.79.22.6777 · Cited by 1,298 · see citing works

The Interferon System

Stewart, W. E. (1979) · Springer eBooks · doi:10.1007/978-3-7091-3432-0 · Cited by 1,165 · see citing works

Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-β gene regulatory elements

Miyamoto, M., Fujita, T., Kimura, Y., Maruyama, M., Harada, H., Sudo, Y., Miyata, T., & Taniguchi, T. (1988) · Cell · doi:10.1016/s0092-8674(88)91307-4 · Cited by 977 · see citing works

Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes

Harada, H., Fujita, T., Miyamoto, M., Kimura, Y., Maruyama, M., Furia, A., Miyata, T., & Taniguchi, T. (1989) · Cell · doi:10.1016/0092-8674(89)90107-4 · Cited by 957 · see citing works

γ-Interferon transcriptionally regulates an early-response gene containing homology to platelet proteins

Luster, A. D., Unkeless, J. C., & Ravetch, J. V. (1985) · Nature · doi:10.1038/315672a0 · Cited by 944 · see citing works

The location of cis-acting regulatory sequences in the human T cell lymphotropic virus type III (HTLV-III/LAV) long terminal repeat

Rosen, C. A., Sodroski, J., & Haseltine, W. A. (1985) · Cell · doi:10.1016/s0092-8674(85)80062-3 · Cited by 824 · see citing works

A human beta-actin expression vector system directs high-level accumulation of antisense transcripts.

Gunning, P. W., Leavitt, J. C., Muscat, G. E. O., Ng, S. Y., & Kedes, L. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.14.4831 · Cited by 739 · see citing works

Retinoic acid induces neuronal differentiation of a cloned human embryonal carcinoma cell line in vitro

Andrews, P. W. (1984) · Developmental Biology · doi:10.1016/0012-1606(84)90316-6 · Cited by 670 · see citing works

The interferon system. A bird's eye view of its biochemistry.

Sen, G. C., & Lengyel, P. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42719-6 · Cited by 633 · see citing works

Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control.Preprint

Levy, D. E., Kessler, D. S., Pine, R. I., Reich, N. C., & Darnell, J. E., Jr. (1988) · Genes & Development · doi:10.1101/gad.2.4.383 · Cited by 559 · see citing works

α-Interferon-induced transcription of HLA and metallothionein genes containing homologous upstream sequences

Friedman, R. L., & Stark, G. R. (1985) · Nature · doi:10.1038/314637a0 · Cited by 491 · see citing works

ISGF3, the transcriptional activator induced by interferon alpha, consists of multiple interacting polypeptide chains.

Fu, X.-Y., Kessler, D. S., Veals, S. A., Levy, D. E., & Darnell, J. E., Jr. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.21.8555 · Cited by 490 · see citing works

Cytoplasmic activation of ISGF3, the positive regulator of interferon-alpha-stimulated transcription, reconstituted in vitro.Preprint

Levy, D. E., Kessler, D. S., Pine, R. I., & Darnell, J. E., Jr. (1989) · Genes & Development · doi:10.1101/gad.3.9.1362 · Cited by 468 · see citing works

The complete sequence of a full length cDNA for human liver glyceraldehyde-3-phosphate dehydrogenase: evidence for multiple mRNA species

Arcari, P., Martinelli, R., & Salvatore, F. (1984) · Nucleic Acids Research · doi:10.1093/nar/12.23.9179 · Cited by 409 · see citing works

Subunit of an Alpha-Interferon-Responsive Transcription Factor Is Related to Interferon Regulatory Factor and Myb Families of DNA-Binding Proteins

Veals, S. A., Schindler, C., Leonard, D. G. B., Fu, X.-Y., Aebersold, R. H., Darnell, J. E., Jr., & Levy, D. E. (1992) · Molecular and Cellular Biology · doi:10.1128/mcb.12.8.3315 · Cited by 389 · see citing works

Use of a Selectable Marker Regulated by Alpha Interferon To Obtain Mutations in the Signaling Pathway

Pellegrini, S., John, J., Shearer, M., Kerr, I. M., & Stark, G. R. (1989) · Molecular and Cellular Biology · doi:10.1128/mcb.9.11.4605 · Cited by 374 · see citing works

Cytoplasmic activation of GAF, an IFN‐gamma‐regulated DNA‐binding factor.

Decker, T., Lew, D. J., Mirkovitch, J., & Darnell, J. E., Jr. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb08026.x · Cited by 369 · see citing works

Absence of the type I IFN system in EC cells: Transcriptional activator (IRF-1) and repressor (IRF-2) genes are developmentally regulated

Harada, H., Willison, K. R., Sakakibara, J., Miyamoto, M., Fujita, T., & Taniguchi, T. (1990) · Cell · doi:10.1016/0092-8674(90)90163-9 · Cited by 368 · see citing works

Interferon gamma plays a critical role in induced cell death of effector T cell: a possible third mechanism of self-tolerance.

Liu, Y., & Janeway, C. A. (1990) · The Journal of Experimental Medicine · doi:10.1084/jem.172.6.1735 · Cited by 361 · see citing works

Induction of endogenous IFN-α and IFN-β genes by a regulatory transcription factor, IRF-1

Fujita, T., Kimura, Y., Miyamoto, M., Barsoumian, E. L., & Taniguchi, T. (1989) · Nature · doi:10.1038/337270a0 · Cited by 358 · see citing works

An interferon gamma-regulated protein that binds the interferon-inducible enhancer element of major histocompatibility complex class I genes.

Driggers, P. H., Ennist, D. L., Gleason, S. L., Mak, W. H., Marks, M. S., Levi, B. Z., Flanagan, J. R., Appella, E., & Ozato, K. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.10.3743 · Cited by 356 · see citing works

Identification and characterization of a novel repressor of beta-interferon gene expression.Preprint

Keller, A., & Maniatis, T. (1991) · Genes & Development · doi:10.1101/gad.5.5.868 · Cited by 345 · see citing works

Purification and Cloning of Interferon-Stimulated Gene Factor 2 (ISGF2): ISGF2 (IRF-1) Can Bind to the Promoters of Both Beta Interferon- and Interferon-Stimulated Genes but Is Not a Primary Transcriptional Activator of Either

Pine, R. I., Decker, T., Kessler, D. S., Levy, D. E., & Darnell, J. E., Jr. (1990) · Molecular and Cellular Biology · doi:10.1128/mcb.10.6.2448 · Cited by 331 · see citing works

Human β-interferon gene expression is regulated by an inducible enhancer element

Goodbourn, S., Zinn, K., & Maniatis, T. (1985) · Cell · doi:10.1016/s0092-8674(85)80024-6 · Cited by 286 · see citing works

Interferon-activated genes

Revel, M., & Chebath, J. (1986) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(86)90134-9 · Cited by 284 · see citing works

Overlapping Elements in the Guanylate-Binding Protein Gene Promoter Mediate Transcriptional Induction by Alpha and Gamma Interferons

Lew, D. J., Decker, T., Strehlow, I., & Darnell, J. E., Jr. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.1.182 · Cited by 280 · see citing works

A single DNA response element can confer inducibility by both alpha- and gamma-interferons.

Reid, L. E., Brasnett, A. H., Gilbert, C. S., Porter, A. C. G., Gewert, D. R., Stark, G. R., & Kerr, I. M. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.3.840 · Cited by 257 · see citing works

Critical role of a common transcription factor, IRF‐1, in the regulation of IFN‐beta and IFN‐inducible genes.

Reis, L. F. L., Harada, H., Wolchok, J. D., Taniguchi, T., & Vilček, J. (1992) · The EMBO Journal · doi:10.1002/j.1460-2075.1992.tb05041.x · Cited by 243 · see citing works

IL-2 and IFN-gamma are two necessary lymphokines in the development of cytolytic T cells.

Maraskovsky, E., Chen, W. F., & Shortman, K. (1989) · The Journal of Immunology · doi:10.4049/jimmunol.143.4.1210 · Cited by 240 · see citing works

The regulation and expression of MHC class I genes

David‐Watine, B., Israël, A., & Kourilsky, P. (1990) · Immunology Today · doi:10.1016/0167-5699(90)90114-o · Cited by 233 · see citing works

Overlapping positive and negative regulatory domains of the human beta-interferon gene.

Goodbourn, S., & Maniatis, T. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.5.1447 · Cited by 232 · see citing works

γ-Interferon is one of several direct B cell-maturing lymphokines

Sidman, C. L., Marshall, J. D., Shultz, L. D., Gray, P. W., & Johnson, H. M. (1984) · Nature · doi:10.1038/309801a0 · Cited by 232 · see citing works

Interferon response sequence potentiates activity of an enhancer in the promoter region of a mouse H–2 gene

Israël, A., Kimura, A., Fournier, A., Fellous, M., & Kourilsky, P. (1986) · Nature · doi:10.1038/322743a0 · Cited by 229 · see citing works

Interferon-β gene regulation: Tandemly repeated sequences of a synthetic 6 bp oligomer function as a virus-inducible enhancer

Fujita, T., Shibuyà, H., Hotta, H., Yamanishi, K., & Taniguchi, T. (1987) · Cell · doi:10.1016/0092-8674(87)90288-1 · Cited by 216 · see citing works

Synergistic interaction between interferon‐alpha and interferon‐gamma through induced synthesis of one subunit of the transcription factor ISGF3.

Levy, D. E., Lew, D. J., Decker, T., Kessler, D. S., & Darnell, J. E., Jr. (1990) · The EMBO Journal · doi:10.1002/j.1460-2075.1990.tb08216.x · Cited by 212 · see citing works

Delimitation and properties of DNA sequence: required for the regulated expression of human interferon-β gene

Fujita, T., Ohno, S., Yasumitsu, H., & Taniguchi, T. (1985) · Cell · doi:10.1016/s0092-8674(85)80022-2 · Cited by 208 · see citing works

Transcriptional induction by interferon. New protein(s) determine the extent and length of the induction.

Larner, A. C., Chaudhuri, A., & Darnell, J. E., Jr. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)42492-6 · Cited by 205 · see citing works

Interferon‐induced binding of nuclear factors to promoter elements of the 2‐5A synthetase gene.

Rutherford, M., Hannigan, G. E., & Williams, B. (1988) · The EMBO Journal · doi:10.1002/j.1460-2075.1988.tb02872.x · Cited by 189 · see citing works

Transcriptional regulation of interferon-stimulated genes.

Williams, B. R. G. (1991) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1991.tb21041.x · Cited by 179 · see citing works

A 46-nucleotide promoter segment from an IFN-α gene renders an unrelated promoter inducible by virus

Ryals, J. A., Dierks, P. M., Ragg, H., & Weissmann, C. (1985) · Cell · doi:10.1016/s0092-8674(85)80023-4 · Cited by 178 · see citing works

Interferon-induced transcription of a major histocompatibility class I gene accompanies binding of inducible nuclear factors to the interferon consensus sequence.

Shirayoshi, Y., Burke, P., Appella, E., & Ozato, K. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.16.5884 · Cited by 163 · see citing works

Different pathways mediate virus inducibility of the human IFN-α1 and IFN-β genes

MacDonald, N. J., Kuhl, D., Maguire, D. J., Näf, D., Gallant, P., Goswamy, A., Hug, H., Büeler, H., Chaturvedi, M. M., de la Fuente, J., et al. (1990) · Cell · doi:10.1016/0092-8674(90)90091-r · Cited by 151 · see citing works

Interferon-Responsive Regulatory Elements in the Promoter of the Human 2′,5′-Oligo(A) Synthetase Gene

Benech, P. D., Vigneron, M., Peretz, D., Revel, M., & Chebath, J. (1987) · Molecular and Cellular Biology · doi:10.1128/mcb.7.12.4498 · Cited by 138 · see citing works

Two distinct alpha-interferon-dependent signal transduction pathways may contribute to activation of transcription of the guanylate-binding protein gene.

Decker, T., Lew, D. J., & Darnell, J. E., Jr. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.10.5147 · Cited by 129 · see citing works

ABSENCE OF SEROLOGICALLY DETECTABLE H-2 ON PRIMITIVE TERATOCARCINOMA CELLS IN CULTURE

Artzt, K., & Jacob, F. (1974) · Transplantation · doi:10.1097/00007890-197406000-00015 · Cited by 126 · see citing works

Overlapping sites for constitutive and induced DNA binding factors involved in interferon‐stimulated transcription.

Dale, T. C., Rosen, J. M., Guille, M., Lewin, A. R., Porter, A., Kerr, I. M., & Stark, G. R. (1989) · The EMBO Journal · doi:10.1002/j.1460-2075.1989.tb03444.x · Cited by 121 · see citing works

Induction of HLA class II genes by IFN-gamma is transcriptional and requires a trans-acting protein.

Amaldi, I., Reith, W., Berte, C. C., & Mach, B. (1989) · The Journal of Immunology · doi:10.4049/jimmunol.142.3.999 · Cited by 111 · see citing works

Involvement of acis-element that binds an H2TF-l/NFxB like factor(s) in the virus-induced interferon-β gene expression

Fujita, T., Miyamoto, M., Kimura, Y., Hammer, J., & Taniguchi, T. (1989) · Nucleic Acids Research · doi:10.1093/nar/17.9.3335 · Cited by 105 · see citing works

Interferons Increase Transcription of a Major Histocompatibility Class I Gene Via a 5′ Interferon Consensus Sequence

Sugita, K., Miyazaki, J., Appella, E., & Ozato, K. (1987) · Molecular and Cellular Biology · doi:10.1128/mcb.7.7.2625 · Cited by 105 · see citing works

Identification of an inducible factor that binds to a positive regulatory element of the human beta-interferon gene.

Keller, A., & Maniatis, T. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.10.3309 · Cited by 104 · see citing works

A gamma‐interferon‐induced factor that binds the interferon response sequence of the MHC class I gene, H‐2Kb.

Blanar, M. A., Baldwin, A. S., Flavell, R. A., & Sharp, P. A. (1989) · The EMBO Journal · doi:10.1002/j.1460-2075.1989.tb03484.x · Cited by 103 · see citing works

Complete nucleotide sequence of the murine H-2kkgene. Comparison of three H-2K locus alleles

Arnold, B., Burgert, H.-G., Archibald, A. L., & Kvist, S. (1984) · Nucleic Acids Research · doi:10.1093/nar/12.24.9473 · Cited by 103 · see citing works

The HLA-AW24 gene: Sequence, surroundings and comparison with the HLA-A2 and HLA-A3 genes

Nguyen, C., Sodoyer, R., Trucy, J., Strachan, T., & Jordan, B. (1985) · Immunogenetics · doi:10.1007/bf00430931 · Cited by 94 · see citing works

Interferon-dependent transcriptional activation: signal transduction without second messenger involvement?

Levy, D. E., & Darnell, J. E., Jr. (1990) · PubMed · Cited by 90 · see citing works

5' regulatory region of a novel cytokine gene mediates selective activation by interferon gamma.

Wright, T. M., & Farber, J. M. (1991) · The Journal of Experimental Medicine · doi:10.1084/jem.173.2.417 · Cited by 80 · see citing works

Sequence of a cDNA coding for human IRF-1

Maruyama, M., Fujita, T., & Taniguchi, T. (1989) · Nucleic Acids Research · doi:10.1093/nar/17.8.3292 · Cited by 77 · see citing works

Occupancy of Upstream Regulatory Sites In Vivo Coincides with Major Histocompatibility Complex Class I Gene Expression in Mouse Tissues

Dey, A., Thornton, A. M., Lonergan, M., Weissman, S. M., Chamberlain, J. W., & Ozato, K. (1992) · Molecular and Cellular Biology · doi:10.1128/mcb.12.8.3590 · Cited by 76 · see citing works

The control of interferon‐inducible gene expression

Kerr, I. M., & Stark, G. R. (1991) · FEBS Letters · doi:10.1016/0014-5793(91)80802-a · Cited by 70 · see citing works

Modulation of interferon consensus sequence binding protein mRNA in murine peritoneal macrophages. Induction by IFN-gamma and down-regulation by IFN-alpha, dexamethasone, and protein kinase inhibitors

Politis, A. D., Sivo, J., Driggers, P. H., Ozato, K., & Vogel, S. N. (1992) · The Journal of Immunology · doi:10.4049/jimmunol.148.3.801 · Cited by 68 · cited 4× · see citing works

Gene induction by interferons: functional complementation between trans-acting factors induced by alpha interferon and gamma interferon.

Bandyopadhyay, S. K., Kalvakolanu, D. V., & Sen, G. C. (1990) · Molecular and Cellular Biology · doi:10.1128/mcb.10.10.5055 · Cited by 67 · see citing works

Interferon synthesis in the early post-implantation mouse embryo

Barlow, D. P., Randle, B. J., & Burke, D. C. (1984) · Differentiation · doi:10.1111/j.1432-0436.1984.tb01433.x · Cited by 66 · see citing works

Interferon induction of gene transcription analyzed by in vivo footprinting.

Mirkovitch, J., Decker, T., & Darnell, J. E. (1992) · Molecular and Cellular Biology · doi:10.1128/mcb.12.1.1 · Cited by 63 · see citing works

Retinoic acid-dependent transactivation of major histocompatibility complex class I promoters by the nuclear hormone receptor H-2RIIBP in undifferentiated embryonal carcinoma cells.

Nagata, T., Segars, J. H., Levi, B. Z., & Ozato, K. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.3.937 · Cited by 60 · see citing works

Interferon‐γ is not an antiviral, but a growth‐promoting factor for t lymphocytes

Landolfo, S., Gariglio, M., Gribaudo, G., Jemma, C., Giovarelli, M., & Cavallo, G. (1988) · European Journal of Immunology · doi:10.1002/eji.1830180403 · Cited by 59 · see citing works

Dissection of the interferon gamma‐MHC class II signal transduction pathway reveals that type I and type II interferon systems share common signalling component(s).

Loh, J. E., Chang, C., Fodor, W. L., & Flavell, R. A. (1992) · The EMBO Journal · doi:10.1002/j.1460-2075.1992.tb05180.x · Cited by 55 · see citing works

Differential effects of type I IFN and IFN-gamma on the binding of tumor necrosis factor to receptors in two human cell lines.

Tsujimoto, M., Feinman, R., & Vilček, J. (1986) · The Journal of Immunology · doi:10.4049/jimmunol.137.7.2272 · Cited by 53 · see citing works

Molecular cloning and characterization of interferon alpha/beta response element binding factors of the murine (2'-5')oligoadenylate synthetase ME-12 gene.

Yan, C., & Tamm, I. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.1.144 · Cited by 49 · see citing works

Negative regulation of the major histocompatibility complex class I promoter in embryonal carcinoma cells.

Flanagan, J. R., Murata, M., Burke, P., Shirayoshi, Y., Appella, E., Sharp, P. A., & Ozato, K. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.8.3145 · Cited by 42 · see citing works

Induction of major histocompatibility class I antigens by interferons in undifferentiated F9 cells

Wan, Y. Y., Orrison, B. M., Lieberman, R., Lazarovici, P., & Ozato, K. (1987) · Journal of Cellular Physiology · doi:10.1002/jcp.1041300214 · Cited by 40 · see citing works

Sequence of a cDNA coding for human IRF-2

Itoh, S., Harada, H., Fujita, T., MIMURA, T., & Taniguchi, T. (1989) · Nucleic Acids Research · doi:10.1093/nar/17.20.8372 · Cited by 37 · see citing works

Enhancer functions andin vitroprotein binding of native and mutated interferon-responsive sequences

Cohen, B., Vaiman, D., & Chebath, J. (1989) · Nucleic Acids Research · doi:10.1093/nar/17.4.1679 · Cited by 30 · see citing works

Induction of class I major histocompatibility complex antigens in human teratocarcinoma cells by interferon without induction of differentiation, growth inhibition, or resistance to viral infection.

Andrews, P. W., Trinchieri, G., PERUSSIA, B., & Baglioni, C. (1987) · PubMed · Cited by 29 · see citing works

Two upstream elements activate transcription of a major histocompatibility complex class I genein vitro

Driggers, P. H., Elenbaas, B., An, J., Lee, I. J., & Ozato, K. (1992) · Nucleic Acids Research · doi:10.1093/nar/20.10.2533 · Cited by 26 · see citing works

Regulation of major histocompatibility complex class I genes.

Burke, P., & Ozato, K. (1989) · PubMed · Cited by 21 · see citing works

Control of β-Interferon Expression in Murine Embryonal Carcinoma F9 Cells

Francis, M. K., & Lehman, J. M. (1989) · Molecular and Cellular Biology · doi:10.1128/mcb.9.8.3553-3556.1989 · Cited by 19 · see citing works

HOW CELLS RESPOND TO INTERFERONS

Stark, G. R., Kerr, I. M., Williams, B. R. G., Silverman, R. H., & Schreiber, R. D. (1998) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.67.1.227 · Cited by 3,932 · see citing works

CELLULAR RESPONSES TO INTERFERON-γ

Boehm, U., Klamp, T., Groot, M., & Howard, J. C. (1997) · Annual Review of Immunology · doi:10.1146/annurev.immunol.15.1.749 · Cited by 2,890 · see citing works

IRF Family of Transcription Factors as Regulators of Host Defense

Taniguchi, T., Ogasawara, K., Takaoka, A., & Tanaka, N. (2001) · Annual Review of Immunology · doi:10.1146/annurev.immunol.19.1.623 · Cited by 1,658 · see citing works

Interferons: cell signalling, immune modulation, antiviral response and virus countermeasures

Goodbourn, S., Didcock, L., & Randall, R. E. (2000) · Journal of General Virology · doi:10.1099/0022-1317-81-10-2341 · Cited by 977 · see citing works

Immunodeficiency and Chronic Myelogenous Leukemia-like Syndrome in Mice with a Targeted Mutation of the ICSBP Gene

Holtschke, T., Löhler, J., Kanno, Y., Fehr, T., Giese, N., Rosenbauer, F., Lou, J., Knobeloch, K.-P., Gabriele, L., Waring, J. F., et al. (1996) · Cell · doi:10.1016/s0092-8674(00)81348-3 · Cited by 644 · see citing works

Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development

Matsuyama, T., Kimura, T., Kitagawa, M., Pfeffer, K., Kawakami, T., Watanabe, N., Kündig, T. M., Amakawa, R., Kishihara, K., Wakeham, A., et al. (1993) · Cell · doi:10.1016/s0092-8674(05)80086-8 · Cited by 649 · see citing works

Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activityPreprint

Ronco, L. V., Karpova, A. Y., Vidal, M., & Howley, P. M. (1998) · Genes & Development · doi:10.1101/gad.12.13.2061 · Cited by 631 · see citing works

Interferon regulatory factors: the next generation

Mamane, Y., Heylbroeck, C., Génin, P., Algarté-Génin, M., Servant, M. J., Page, C. L., DeLuca, C., Kwon, H., Lin, R., & Hiscott, J. B. (1999) · Gene · doi:10.1016/s0378-1119(99)00262-0 · Cited by 570 · see citing works

The growing family of interferon regulatory factors

Nguyen, H., Hiscott, J., & Pitha, P. M. (1997) · Cytokine & Growth Factor Reviews · doi:10.1016/s1359-6101(97)00019-1 · Cited by 480 · see citing works

Pip, a novel IRF family member, is a lymphoid-specific, PU.1-dependent transcriptional activator.

Eisenbeis, C. F., Singh, H., & Storb, U. (1995) · Genes & Development · doi:10.1101/gad.9.11.1377 · Cited by 447 · see citing works

Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes.

Au, W.-C., Moore, P. A., Lowther, W. J., Juang, Y., & Pitha, P. M. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.25.11657 · Cited by 388 · see citing works

Regulation of Macrophage Chemokine Expression by Lipopolysaccharide In Vitro and In Vivo

Kopydlowski, K. M., Salkowski, C. A., Cody, M. J., van Rooijen, N., Major, J. A., Hamilton, T. A., & Vogel, S. N. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.163.3.1537 · Cited by 311 · see citing works

Regulation of Type I Interferon Gene Expression by Interferon Regulatory Factor-3

Schafer, S. L., Lin, R., Moore, P. A., Hiscott, J. B., & Pitha, P. M. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.5.2714 · Cited by 266 · see citing works

Review: Activities of IRF-1

Kröger, A., Köster, M., Schroeder, K., Häuser, H., & Mueller, P. P. (2002) · Journal of Interferon & Cytokine Research · doi:10.1089/107999002753452610 · Cited by 265 · see citing works

Pip, a lymphoid-restricted IRF, contains a regulatory domain that is important for autoinhibition and ternary complex formation with the Ets factor PU.1.

Brass, A. L., Kehrli, E., Eisenbeis, C. F., Storb, U., & Singh, H. (1996) · Genes & Development · doi:10.1101/gad.10.18.2335 · Cited by 242 · see citing works

PU.1 and Interferon Consensus Sequence-binding Protein Regulate the Myeloid Expression of the Human Toll-like Receptor 4 Gene

Rehli, M., Poltorak, A., Schwarzfischer, L., Krause, S. W., Andreesen, R., & Beutler, B. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.13.9773 · Cited by 233 · see citing works

Molecular cloning ofLSIRF, a lymphoid-specific member of the interferon regulatory factor family that binds the interferon-stimulated response element (ISRE)

Matsuyama, T., Grossman, A., Mittrücker, H.-W., Siderovski, D. P., Kiefer, F., Kawakami, T., Richardson, C. D., Taniguchi, T., Yoshinaga, S. K., & Mak, T. W. (1995) · Nucleic Acids Research · doi:10.1093/nar/23.12.2127 · Cited by 232 · see citing works

Interleukin‐4 and Interferon‐γ: The Quintessence of a Mutual Antagonistic Relationship

Paludan (1998) · Scandinavian Journal of Immunology · doi:10.1046/j.1365-3083.1998.00435.x · Cited by 219 · see citing works

Interferon Consensus Sequence Binding Protein–deficient Mice Display Impaired Resistance to Intracellular Infection Due to a Primary Defect in Interleukin 12 p40 Induction

Scharton-Kersten, T., Contursi, C., Masumi, A., Sher, A., & Ozato, K. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.186.9.1523 · Cited by 217 · see citing works

Roles of interferon-regulatory factors in T-helper-cell differentiation

Lohoff, M. D., & Mak, T. W. (2005) · Nature reviews. Immunology · doi:10.1038/nri1552 · Cited by 214 · see citing works

Functional Analysis of Human Herpesvirus 8-Encoded Viral Interferon Regulatory Factor 1 and Its Association with Cellular Interferon Regulatory Factors and p300

Burýšek, L., Yeow, W.-S., Lubyová, B., Kellum, M. J., Schafer, S. L., Huang, Y. Q., & Pitha, P. M. (1999) · Journal of Virology · doi:10.1128/jvi.73.9.7334-7342.1999 · Cited by 212 · see citing works

Assembly requirements of PU.1–Pip (IRF‐4) activator complexes: inhibiting function in vivo using fused dimers

Brass, A. L., Zhu, A. Q., & Singh, H. (1999) · The EMBO Journal · doi:10.1093/emboj/18.4.977 · Cited by 207 · see citing works

The Multiple Roles of Interferon Regulatory Factor family in Health and Disease

Wang, L., Zhu, Y., Zhang, N., Xian, Y., Tang, Y., Ye, J., Reza, F., He, G., Wen, X., & Jiang, X. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01980-4 · Cited by 178 · see citing works

A Novel Interferon Regulatory Factor Family Transcription Factor, ICSAT/Pip/LSIRF, That Negatively Regulates the Activity of Interferon-Regulated Genes

Yamagata, T., Nishida, J., Tanaka, T., Sakai, R., Mitani, K., Yoshida, M., Taniguchi, T., Yazaki, Y., & Hirai, H. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.4.1283 · Cited by 196 · see citing works

An IFN-γ-Inducible Transcription Factor, IFN Consensus Sequence Binding Protein (ICSBP), Stimulates IL-12 p40 Expression in Macrophages

Wang, I.-M., Contursi, C., Masumi, A., Ma, X., Trinchieri, G., & Ozato, K. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.165.1.271 · Cited by 187 · see citing works

Review: ICSBP/IRF-8: Its Regulatory Roles in the Development of Myeloid Cells

Tamura, T., & Ozato, K. (2002) · Journal of Interferon & Cytokine Research · doi:10.1089/107999002753452755 · Cited by 183 · see citing works

The genomic structure of the murine ICSBP gene reveals the presence of the gamma interferon-responsive element, to which an ISGF3 alpha subunit (or similar) molecule binds.

Kanno, Y., Kozak, C. A., Schindler, C., Driggers, P. H., Ennist, D. L., Gleason, S. L., Darnell, J. E., & Ozato, K. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.7.3951 · Cited by 180 · see citing works

Deficiency in the Transcription Factor Interferon Regulatory Factor (Irf)-2 Leads to Severely Compromised Development of Natural Killer and T Helper Type 1 Cells

Lohoff, M. D., Duncan, G. S., Ferrick, D. A., Mittrücker, H., Bischof, S., Prechtl, S., Röllinghoff, M., Schmitt, E., Pahl, A. M., & Mak, T. W. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.3.325 · Cited by 174 · see citing works

Characterization of a Novel Human Herpesvirus 8-Encoded Protein, vIRF-3, That Shows Homology to Viral and Cellular Interferon Regulatory Factors

Lubyová, B., & Pitha, P. M. (2000) · Journal of Virology · doi:10.1128/jvi.74.17.8194-8201.2000 · Cited by 174 · see citing works

Kaposi’s Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor

Li, M., Lee, H., Guo, J., Neipel, F., Ozato, K., Jung, J. U., Fleckenstein, B., Jae, & Jung, U. (1997) · Cited by 171 · see citing works

Molecular interactions between interferon consensus sequence binding protein and members of the interferon regulatory factor family.

Bovolenta, C., Driggers, P. H., Marks, M. S., Medin, J. A., Politis, A. D., Vogel, S. N., Levy, D. E., Sakaguchi, K., Appella, E., & Coligan, J. E. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.11.5046 · Cited by 167 · see citing works

Crucial Role of Interferon Consensus Sequence Binding Protein, but neither of Interferon Regulatory Factor 1 nor of Nitric Oxide Synthesis for Protection Against Murine Listeriosis

Fehr, T., Schoedon, G., Odermatt, B., Holtschke, T., Schneemann, M., Bachmann, M. F., Mak, T. W., Horak, I., & Zinkernagel, R. M. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.185.5.921 · Cited by 162 · see citing works

Phosphorylation Events Modulate the Ability of Interferon Consensus Sequence Binding Protein to Interact with Interferon Regulatory Factors and to Bind DNA

Sharf, R., Meraro, D., Azriel, A., Thornton, A. M., Ozato, K., Petricoin, E. F., Larner, A. C., Schaper, F., Hauser, H., & Levi, B.-Z. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.15.9785 · Cited by 162 · see citing works

Interferon (IFN) Consensus Sequence-binding Protein, a Transcription Factor of the IFN Regulatory Factor Family, Regulates Immune Responses In Vivo through Control of Interleukin 12 Expression

Giese, N. A., Gabriele, L., Doherty, T. M., Klinman, D. M., Tadesse-Heath, L., Contursi, C., Epstein, S. L., & Morse, H. C. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.186.9.1535 · Cited by 160 · see citing works

Interferon Regulatory Factor-2 Is a Transcriptional Activator in Muscle Where It Regulates Expression of Vascular Cell Adhesion Molecule-1

Jesse, T. L., LaChance, R., Iademarco, M. F., & Dean, D. C. (1998) · Journal of Cell Biology · doi:10.1083/jcb.140.5.1265 · Cited by 167 · see citing works

Cytomegalovirus Activates Interferon Immediate-Early Response Gene Expression and an Interferon Regulatory Factor 3-Containing Interferon-Stimulated Response Element-Binding Complex

Navarro, L., Mowen, K., Rodems, S. M., Weaver, B. K., Reich, N., Spector, D., & David, M. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.7.3796 · Cited by 191 · see citing works

Regulation of LMP2 and TAP1 Genes by IRF-1 Explains the Paucity of CD8+ T Cells in IRF-1−/− Mice

White, L. C., Wright, K. L., Felix, N. J., Ruffner, H., Reis, L. F. L., Pine, R. I., & Ting, J. P. ‐. (1996) · Immunity · doi:10.1016/s1074-7613(00)80262-9 · Cited by 157 · see citing works

Kaposi’s Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor

Li, M., Lee, H., Guo, J., Neipel, F., Fleckenstein, B., Ozato, K., & Jung, J. U. (1998) · Journal of Virology · doi:10.1128/jvi.72.7.5433-5440.1998 · Cited by 151 · see citing works

Regulation of MHC class I and II gene transcription: differences and similarities

van den Elsen, P. J., Gobin, S. J. P., van Eggermond, M. C. J. A., & Peijnenburg, A. (1998) · Immunogenetics · doi:10.1007/s002510050425 · Cited by 150 · see citing works

Interferon regulatory factor family of transcription factors and regulation of oncogenesis

Takaoka, A., Tamura, T., & Taniguchi, T. (2008) · Cancer Science · doi:10.1111/j.1349-7006.2007.00720.x · Cited by 150 · see citing works

IRF8 inhibits C/EBPα activity to restrain mononuclear phagocyte progenitors from differentiating into neutrophils

Kurotaki, D., Yamamoto, M., Nishiyama, A., Uno, K., Ban, T., Ichino, M., Sasaki, H., Matsunaga, S., Yoshinari, M., Ryo, A., et al. (2014) · Nature Communications · doi:10.1038/ncomms5978 · Cited by 149 · see citing works

Protein-Protein and DNA-Protein Interactions Affect the Activity of Lymphoid-Specific IFN Regulatory Factors

Meraro, D., Hashmueli, S., Koren, B., Azriel, A., Oumard, A., Kirchhoff, S., Hauser, H., Nagulapalli, S., Atchison, M. L., & Levi, B.-Z. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.163.12.6468 · Cited by 147 · see citing works

Molecular virology of Kaposi's sarcoma–associated herpesvirus

Moore, P. S., & Chang, Y. (2001) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2000.0777 · Cited by 147 · see citing works

Expression of Interferon Consensus Sequence Binding Protein (ICSBP) Is Downregulated in Bcr-Abl-Induced Murine Chronic Myelogenous Leukemia-Like Disease, and Forced Coexpression of ICSBP Inhibits Bcr-Abl-Induced Myeloproliferative Disorder

Hao, S. X., & Ren, R. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.4.1149-1161.2000 · Cited by 143 · see citing works

An overview of the interferon system: signal transduction and mechanisms of action.

Kalvakolanu, D., & Borden, E. (1996) · Cancer Investigation · doi:10.3109/07357909609018435 · Cited by 143 · see citing works

IFN-γ-Induced TNF-α Expression Is Regulated by Interferon Regulatory Factors 1 and 8 in Mouse Macrophages

Sol, V. V., Punzón, C., & Fresno, M. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.181.7.4461 · Cited by 138 · see citing works

Interleukin-10 Inhibits Tumor Metastasis, Downregulates MHC Class I, and Enhances NK Lysis

Kundu, N., & Fulton, A. M. (1997) · Cellular Immunology · doi:10.1006/cimm.1997.1176 · Cited by 141 · see citing works

IRF-8/Interferon (IFN) Consensus Sequence-binding Protein Is Involved in Toll-like Receptor (TLR) Signaling and Contributes to the Cross-talk between TLR and IFN-γ Signaling Pathways

Zhao, J., Kong, H. J., Li, H., Huang, B., Yang, M., Zhu, C. Y., Bogunovic, M., Zheng, F., Mayer, L., Ozato, K., et al. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m507788200 · Cited by 140 · see citing works

Interferon regulatory factor 1 (IRF-1) mediates cell growth inhibition by transactivation of downstream target genes

Kirchhoff, S., Schaper, F., & Häuser, H. (1993) · Nucleic Acids Research · doi:10.1093/nar/21.12.2881 · Cited by 138 · see citing works

Impaired Innate Host Defense Causes Susceptibility to Respiratory Virus Infections in Cystic Fibrosis

Zheng, S., De, B. P., Choudhary, S., Comhair, S. A. A., Goggans, T., Slee, R., Williams, B. R. G., Pilewski, J., Haque, S. J., & Erzurum, S. C. (2003) · Immunity · doi:10.1016/s1074-7613(03)00114-6 · Cited by 125 · see citing works

The Histone Acetylase PCAF Is a Phorbol-Ester-Inducible Coactivator of the IRF Family That Confers Enhanced Interferon Responsiveness

Masumi, A., Wang, I.-M., Lefebvre, B., Yang, X.-J., Nakatani, Y., & Ozato, K. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.3.1810 · Cited by 124 · see citing works

IL-12 Is Dysregulated in Macrophages from IRF-1 and IRF-2 Knockout Mice

Salkowski, C. A., Kopydlowski, K., Blanco, J., Cody, M. J., McNally, R., & Vogel, S. N. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.163.3.1529 · Cited by 119 · see citing works

Regulation of Apoptosis in Myeloid Cells by Interferon Consensus Sequence–Binding Protein

Gabriele, L., Phung, J., Fukumoto, J., Segal, D., Wang, I.-M., Giannakakou, P., Giese, N. A., Ozato, K., & Morse, H. C. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.190.3.411 · Cited by 114 · see citing works

Genomic response to interferon-α in chimpanzees: Implications of rapid downregulation for hepatitis C kinetics

Lanford, R. E., Guerra, B., Lee, H., Chavez, D., Brasky, K. M., & Bigger, C. B. (2006) · Hepatology · doi:10.1002/hep.21167 · Cited by 112 · see citing works

PU.1 and Multiple IFN Regulatory Factor Proteins Synergize to Mediate Transcriptional Activation of the Human IL-1β Gene

Marecki, S., Riendeau, C. J., Liang, M. D., & Fenton, M. J. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.11.6829 · Cited by 111 · see citing works

Alternate interferon signaling pathways

Kalvakolanu, D. V. (2003) · Pharmacology & Therapeutics · doi:10.1016/s0163-7258(03)00070-6 · Cited by 106 · see citing works

Why Do So Many Cancer Patients Fail to Respond to Interferon Therapy?

Einhorn, S., & Grandér, D. (1996) · Journal of Interferon & Cytokine Research · doi:10.1089/jir.1996.16.275 · Cited by 101 · see citing works

Functional Domain Analysis of Interferon Consensus Sequence Binding Protein (ICSBP) and Its Association with Interferon Regulatory Factors

Sharf, R., Azriel, A., Lejbkowicz, F., Winograd, S. S., Ehrlich, R., & Levi, B.-Z. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.22.13063 · Cited by 100 · see citing works

Functional domains of interferon regulatory factor I (IRF-1)

Schaper, F., KIRCHHOFF, S., Posern, G., Köster, M., Oumard, A., Sharf, R., Levi, B.-Z., & Häuser, H. (1998) · Biochemical Journal · doi:10.1042/bj3350147 · Cited by 94 · see citing works

A unique palindromic element mediates gamma interferon induction of mig gene expression.

Wong, P., Severns, C. W., Guyer, N. B., & Wright, T. M. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.2.914 · Cited by 88 · see citing works

Differential Expression and Distinct Functions of IFN Regulatory Factor 4 and IFN Consensus Sequence Binding Protein in Macrophages

Marecki, S., Atchison, M. L., & Fenton, M. J. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.163.5.2713 · Cited by 87 · see citing works

IRF‐8/ICSBP and IRF‐1 cooperatively stimulate mouse IL‐12 promoter activity in macrophages

Masumi, A., Tamaoki, S., Wang, I., Ozato, K., & Komuro, K. (2002) · FEBS Letters · doi:10.1016/s0014-5793(02)03556-1 · Cited by 87 · see citing works

PU.1/Pip and Basic Helix Loop Helix Zipper Transcription Factors Interact With Binding Sites in the CD20 Promoter to Help Confer Lineage- and Stage-Specific Expression of CD20 in B Lymphocytes

Himmelmann, A. W., Riva, A., Wilson, G. L., Lucas, B. P., Thévenin, C., & Kehrl, J. H. (1997) · Blood · doi:10.1182/blood.v90.10.3984 · Cited by 84 · see citing works

Differential expression of interferon regulatory factor 1 (IRF-1), IRF-2, and interferon consensus sequence binding protein genes in lipopolysaccharide (LPS)-responsive and LPS-hyporesponsive macrophages

Barber, S. A., Fultz, M. J., Salkowski, C. A., & Vogel, S. N. (1995) · Infection and Immunity · doi:10.1128/iai.63.2.601-608.1995 · Cited by 84 · see citing works

Type I interferons: expression and signalization

Doly, J., Civas, A., Navarro, S., & Uzé, G. (1998) · Cellular and Molecular Life Sciences · doi:10.1007/s000180050240 · Cited by 82 · see citing works

IFN Regulatory Factor 3 in Health and Disease

Petro, T. M. (2020) · The Journal of Immunology · doi:10.4049/jimmunol.2000462 · Cited by 77 · see citing works

Transcriptional regulation of HLA-A and -B: differential binding of members of the Rel and IRF families of transcription factors.

Girdlestone, J., Isamat, M., Gewert, D. R., & Milstein, C. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.24.11568 · Cited by 78 · see citing works

Interferon regulatory factor 8/interferon consensus sequence binding protein is a critical transcription factor for the physiological phenotype of microglia

Horiuchi, M., Wakayama, K., Itoh, A., Kawai, K., Pleasure, D., Ozato, K., & Itoh, T. (2012) · Journal of Neuroinflammation · doi:10.1186/1742-2094-9-227 · Cited by 76 · see citing works

Retinoic acid induces signal transducer and activator of transcription (STAT) 1, STAT2, and p48 expression in myeloid leukemia cells and enhances their responsiveness to interferons.

Matikainen, S., Ronni, T., Lehtonen, A., Sareneva, T., Melén, K., Nordling, S., Levy, D. E., & Julkunen, I. (1997) · PubMed · Cited by 77 · see citing works

PU.1/Interferon Regulatory Factor Interactions; Mechanisms of Transcriptional Regulation

Marecki, S., & Fenton, M. J. (2000) · Cell Biochemistry and Biophysics · doi:10.1385/cbb:33:2:127 · Cited by 74 · see citing works

Drosophila Immunity: A Comparative Analysis of the Rel Proteins Dorsal and Dif in the Induction of the Genes Encoding Diptericin and Cecropin

Groß, I., Georgel, P., Kappler, C., Reichhart, J., & Hoffmann, J. A. (1996) · Nucleic Acids Research · doi:10.1093/nar/24.7.1238 · Cited by 76 · see citing works

Negative regulation of transcription in eukaryotes

Clark, A. R., & Docherty, K. (1993) · Biochemical Journal · doi:10.1042/bj2960521 · Cited by 76 · see citing works

Interferon Consensus Sequence Binding Protein and Interferon Regulatory Factor-4/Pip Form a Complex That Represses the Expression of the Interferon-Stimulated Gene-15 in Macrophages

Rosenbauer, F., Waring, J. F., Foerster, J., Wietstruk, M., Philipp, D., & Horak, I. (1999) · Blood · doi:10.1182/blood.v94.12.4274 · Cited by 76 · see citing works

A complex element regulates IFN-gamma-stimulated monocyte chemoattractant protein-1 gene transcription.

Valente, A. J., Xie, J. F., Abramova, M. A., Wenzel, U. O., Abboud, H. E., & Graves, D. T. (1998) · PubMed · Cited by 74 · see citing works

Constitutive activation of Epstein-Barr virus (EBV) nuclear antigen 1 gene transcription by IRF1 and IRF2 during restricted EBV latency

Schaefer, B. C., Paulson, E. J., Strominger, J., & Speck, S. H. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.2.873 · Cited by 82 · see citing works

IFN consensus sequence binding protein potentiates STAT1-dependent activation of IFNγ-responsive promoters in macrophages

Contursi, C., Wang, I.-M., Gabriele, L., Gadina, M., O'Shea, J., Morse, H. C., & Ozato, K. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.1.91 · Cited by 72 · see citing works

Review: ICSBP/IRF-8 Transactivation: A Tale of Protein-Protein Interaction

Levi, B.-Z., Hashmueli, S., Gleit-Kielmanowicz, M., Azriel, A., & Meraro, D. (2002) · Journal of Interferon & Cytokine Research · doi:10.1089/107999002753452764 · Cited by 70 · see citing works

Gamma Interferon Triggers Interaction between ICSBP (IRF-8) and TEL, Recruiting the Histone Deacetylase HDAC3 to the Interferon-Responsive Element

Kuwata, T., Gongora, C., Kanno, Y., Sakaguchi, K., Tamura, T., Kanno, T., Basrur, V., Martinez, R., Appella, E., Golub, T., et al. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.21.7439-7448.2002 · Cited by 69 · see citing works

A Complex Element Regulates IFN-γ-Stimulated Monocyte Chemoattractant Protein-1 Gene Transcription

Valente, A. J., Xie, J. F., Abramova, M. A., Wenzel, U. O., Abboud, H. E., & Graves, D. T. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.161.7.3719 · Cited by 68 · see citing works

Review: The Role of IRF-4 in Transcriptional Regulation

Marecki, S., & Fenton, M. J. (2002) · Journal of Interferon & Cytokine Research · doi:10.1089/107999002753452737 · Cited by 67 · see citing works

Transcription Factor Pip Can Enhance DNA Binding by E47, Leading to Transcriptional Synergy Involving Multiple Protein Domains

Nagulapalli, S., & Atchison, M. L. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.8.4639 · Cited by 66 · see citing works

Complex Formation of the Interferon (IFN) Consensus Sequence-binding Protein with IRF-1 Is Essential for Murine Macrophage IFN-γ-induced iNOS Gene Expression

Xiong, H., Zhu, C. Y., Li, H., Chen, F., Mayer, L., Ozato, K., Unkeless, J. C., & Plevy, S. E. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m209583200 · Cited by 64 · see citing works

Interferon Regulatory Factors and TFIIB Cooperatively Regulate Interferon-Responsive Promoter Activity In Vivo and In Vitro

Wang, I.-M., Blanco, J. C. G., Tsai, S. Y., Tsai, M.-J., & Ozato, K. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.11.6313 · Cited by 64 · see citing works

IRF8: Mechanism of Action and Health Implications

Moorman, H. R., Reategui-Almonacid, Y., Poschel, D. B., & Liu, K. (2022) · Cells · doi:10.3390/cells11172630 · Cited by 63 · see citing works

Review: The Role of IRF-4 in B and T Cell Activation and Differentiation

Pernis, A. B. (2002) · Journal of Interferon & Cytokine Research · doi:10.1089/107999002753452728 · Cited by 62 · see citing works

Regulation of IFN Consensus Sequence Binding Protein Expression in Murine Macrophages

Kantakamalakul, W., Politis, A. D., Marecki, S., Sullivan, T., Ozato, K., Fenton, M. J., & Vogel, S. N. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.162.12.7417 · Cited by 61 · see citing works

The Genetic Association of Variants in CD6, TNFRSF1A and IRF8 to Multiple Sclerosis: A Multicenter Case-Control Study

The International Multiple Sclerosis Genetics Consortium (2011) · PLoS ONE · doi:10.1371/journal.pone.0018813 · Cited by 74 · see citing works

Interferon and Malignant Disease - How Does it Work and Why Doesn't it Always?

Grandér, D., & Einhorn, S. (1998) · Acta Oncologica · doi:10.1080/028418698430548 · Cited by 58 · see citing works

PU.1, Interferon Regulatory Factor (IRF) 2, and the Interferon Consensus Sequence-binding Protein (ICSBP/IRF8) Cooperate to Activate NF1 Transcription in Differentiating Myeloid Cells

Huang, W., Horvath, E., & Eklund, E. A. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m607760200 · Cited by 58 · see citing works

Deciphering of the Human Interferon-Regulated Proteome by Mass Spectrometry-Based Quantitative Analysis Reveals Extent and Dynamics of Protein Induction and Repression

Megger, D. A., Philipp, J., Le‐Trilling, V. T. K., Sitek, B., & Trilling, M. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01139 · Cited by 56 · see citing works

clRF-3, a new member of the interferon regulatory factor (IRF) family that is rapidly and transiently induced by dsRNA

Grant, C. E., Vasa, M. Z., & Deeley, R. G. (1995) · Nucleic Acids Research · doi:10.1093/nar/23.12.2137 · Cited by 56 · see citing works

Interferon Regulatory Factor 5 in the Pathogenesis of Systemic Lupus Erythematosus

Cham, C. M., Ko, K., & Niewold, T. B. (2012) · Clinical and Developmental Immunology · doi:10.1155/2012/780436 · Cited by 55 · see citing works

The Interferon Consensus Sequence-binding Protein (ICSBP/IRF8) Represses PTPN13 Gene Transcription in Differentiating Myeloid Cells

Huang, W., Zhu, C., Wang, H., Horvath, E., & Eklund, E. A. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m706710200 · Cited by 54 · see citing works

Molecular Characterization ofIn VivoAdjuvant Activity in Ferrets Vaccinated against Influenza Virus

Yuan, F., Rowe, T., Leon, A. J., Banner, D., Danesh, A., Xu, L., Ran, L., Bosinger, S. E., Guan, Y., Chen, H., et al. (2010) · Journal of Virology · doi:10.1128/jvi.02305-09 · Cited by 52 · see citing works

Preferential binding sites for interferon regulatory factors 3 and 7 involved in interferon-A gene transcription

Morin, P., Bragança, J., Bandu, M., Lin, R., Hiscott, J. B., Doly, J., & Civas, A. (2002) · Journal of Molecular Biology · doi:10.1006/jmbi.2001.5401 · Cited by 52 · see citing works

Constitutive activation of SHP2 in mice cooperates with ICSBP deficiency to accelerate progression to acute myeloid leukemia

Konieczna, I. M., Horvath, E., Wang, H., Lindsey, S. C., Saberwal, G. S., Bei, L., Huang, W., Platanias, L. C., & Eklund, E. A. (2008) · Journal of Clinical Investigation · doi:10.1172/jci33742 · Cited by 53 · see citing works

Kaposi’s Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor Confers Resistance to the Antiproliferative Effect of Interferon-α

Flowers, C. C., Flowers, S. P., & Nabel, G. J. (1998) · Molecular Medicine · doi:10.1007/bf03401747 · Cited by 51 · see citing works

Expression of interferon consensus sequence binding protein induces potent immunity against BCR/ABL-induced leukemia

Deng, M., & Daley, G. Q. (2001) · Blood · doi:10.1182/blood.v97.11.3491 · Cited by 50 · see citing works

Virus-mediated induction of interferon A gene requires cooperation between multiple binding factors in the interferon alpha promoter region.

Au, W. C., Su, Y., Raj, N. B., & Pitha, P. M. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)80488-8 · Cited by 50 · see citing works

Co-occupancy of the interferon regulatory element of the class II transactivator (CIITA) Type IV promoter by interferon regulatory factors 1 and 2

Xi, H., Eason, D. D., Ghosh, D., Dovhey, S. E., Wright, K. L., & Blanck, G. (1999) · Oncogene · doi:10.1038/sj.onc.1202969 · Cited by 48 · see citing works

Human interferon consensus sequence binding protein is a negative regulator of enhancer elements common to interferon-inducible genes.

Weisz, A., Marx, P., Sharf, R., Appella, E., Driggers, P. H., Ozato, K., & Levi, B. Z. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)74081-2 · Cited by 152 · see citing works

Molecular interactions between interferon consensus sequence binding protein and members of the interferon regulatory factor family.

Bovolenta, C., Driggers, P. H., Marks, M. S., Medin, J. A., Politis, A. D., Vogel, S. N., Levy, D. E., Sakaguchi, K., Appella, E., & Coligan, J. E. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.11.5046 · Cited by 167 · see citing works

IFN consenus sequence binding protein (ICSBP) is a conditional repressor of IFN inducible promoters

Welsz, A., Kirchhoff, S., & Levi, B.-Z. (1994) · International Immunology · doi:10.1093/intimm/6.8.1125 · Cited by 50 · see citing works

Functional Domain Analysis of Interferon Consensus Sequence Binding Protein (ICSBP) and Its Association with Interferon Regulatory Factors

Sharf, R., Azriel, A., Lejbkowicz, F., Winograd, S. S., Ehrlich, R., & Levi, B.-Z. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.22.13063 · Cited by 100 · see citing works

A Novel Interferon Regulatory Factor Family Transcription Factor, ICSAT/Pip/LSIRF, That Negatively Regulates the Activity of Interferon-Regulated Genes

Yamagata, T., Nishida, J., Tanaka, T., Sakai, R., Mitani, K., Yoshida, M., Taniguchi, T., Yazaki, Y., & Hirai, H. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.4.1283 · Cited by 196 · see citing works