Koonin, Eugene V.

Origin and evolution of the genetic code: The universal enigma

Koonin, E. V., & Novozhilov, A. S. (2009) · IUBMB Life

RNA and protein synthesis mechanismsOrigins and Evolution of Life

Cited by 392

Algorithms for computing parsimonious evolutionary scenarios for genome evolution, the last universal common ancestor and dominance of horizontal gene transfer in the evolution of prokaryotes

Mirkin, B. G., Fenner, T. I., Galperin, M. Y., & Koonin, E. V. (2003) · BMC Evolutionary Biology

Genomics and Phylogenetic StudiesGenome Rearrangement Algorithms

Cited by 368

Did DNA replication evolve twice independently?

Leipe, D. D., Aravind, L., & Koonin, E. V. (1999) · Nucleic Acids Research

Origins and Evolution of LifeGenomics and Phylogenetic Studies

Cited by 351

The origin and early evolution of eukaryotes in the light of phylogenomics

Koonin, E. V. (2010) · Genome Biology

Protist diversity and phylogenyGenomics and Phylogenetic Studies

Cited by 345

Comparative Genomics, Evolution and Origins of the Nuclear Envelope and Nuclear Pore Complex

Mans, B., Anantharaman, V., Aravind, L., & Koonin, E. V. (2004) · Cell Cycle

Nuclear Structure and FunctionChromosomal and Genetic Variations

Cited by 304

A universal trend of amino acid gain and loss in protein evolution

Jordan, I. K., Kondrashov, F. A., Adzhubei, I. A., Wolf, Y. I., Koonin, E. V., Kondrashov, A. S., & Sunyaev, S. (2005) · Nature

RNA and protein synthesis mechanismsEvolution and Genetic Dynamics

Cited by 297

A korarchaeal genome reveals insights into the evolution of the Archaea

Elkins, J. G., Podar, M., Graham, D. E., Makarova, K. S., Wolf, Y., Randau, L., Hedlund, B. P., Brochier-Armanet, C., Kunin, V., Anderson, I., et al. (2008) · Proceedings of the National Academy of Sciences

Genomics and Phylogenetic StudiesMicrobial Community Ecology and Physiology

Cited by 296

Programmable RNA targeting with the single-protein CRISPR effector Cas7-11

Özcan, A., Krajeski, R., Ioannidi, E., Lee, B., Gardner, A., Makarova, K. S., Koonin, E. V., Abudayyeh, O. O., & Gootenberg, J. S. (2021) · Nature

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 263

The origins of phagocytosis and eukaryogenesis

Yutin, N., Wolf, M. Y., Wolf, Y. I., & Koonin, E. V. (2009) · Biology Direct

Protist diversity and phylogenyCellular transport and secretion

Cited by 247

On the origin of the translation system and the genetic code in the RNA world by means of natural selection, exaptation, and subfunctionalization

Wolf, Y. I., & Koonin, E. V. (2007) · Biology Direct

RNA and protein synthesis mechanismsOrigins and Evolution of Life

Cited by 235

Genomes in turmoil: quantification of genome dynamics in prokaryote supergenomes

Puigbò, P., Lobkovsky, A. E., Kristensen, D. M., Wolf, Y. I., & Koonin, E. V. (2014) · BMC Biology

Genomics and Phylogenetic StudiesChromosomal and Genetic Variations

Cited by 232

Evolution of diverse cell division and vesicle formation systems in Archaea

Makarova, K. S., Yutin, N., Bell, S. D., & Koonin, E. V. (2010) · Nature Reviews Microbiology

Bacterial Genetics and BiotechnologyCellular transport and secretion

Cited by 228

Inventing the dynamo machine: the evolution of the F-type and V-type ATPases

Mulkidjanian, A. Y., Makarova, K. S., Galperin, M. Y., & Koonin, E. V. (2007) · Nature Reviews Microbiology

ATP Synthase and ATPases ResearchRNA and protein synthesis mechanisms

Cited by 210

Origin and Evolution of the Universal Genetic Code

Koonin, E. V., & Novozhilov, A. S. (2017) · Annual Review of Genetics

RNA and protein synthesis mechanismsOrigins and Evolution of Life

Cited by 200

Distribution of Protein Folds in the Three Superkingdoms of Life

Wolf, Y. I., Brenner, S. E., Bash, P. A., & Koonin, E. V. (1999) · Genome Research

Protein Structure and DynamicsGenomics and Phylogenetic Studies

Cited by 183

The Tree and Net Components of Prokaryote Evolution

Puigbò, P., Wolf, Y. I., & Koonin, E. V. (2010) · Genome Biology and Evolution

Genomics and Phylogenetic StudiesProtist diversity and phylogeny

Cited by 181

Compact RNA editors with small Cas13 proteins

Kannan, S., Altae-Tran, H., Jin, X., Madigan, V. J., Oshiro, R., Makarova, K. S., Koonin, E. V., & Zhang, F. (2022) · Nature Biotechnology

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 176

Co-evolution of primordial membranes and membrane proteins

Mulkidjanian, A. Y., Galperin, M. Y., & Koonin, E. V. (2009) · Trends in Biochemical Sciences

Origins and Evolution of LifeATP Synthase and ATPases Research

Cited by 169

Evolutionary primacy of sodium bioenergetics

Mulkidjanian, A. Y., Galperin, M. Y., Makarova, K. S., Wolf, Y. I., & Koonin, E. V. (2008) · Biology Direct

ATP Synthase and ATPases ResearchIon Transport and Channel Regulation

Cited by 163

Viruses and mobile elements as drivers of evolutionary transitions

Koonin, E. V. (2016) · Philosophical Transactions of the Royal Society B: Biological Sciences

Evolution and Genetic DynamicsOrigins and Evolution of Life

Cited by 161

Monophyly of class I aminoacyl tRNA synthetase, USPA, ETFP, photolyase, and PP‐ATPase nucleotide‐binding domains: implications for protein evolution in the RNA world

Aravind, L., Anantharaman, V., & Koonin, E. V. (2002) · Proteins: Structure, Function, and Bioinformatics

RNA and protein synthesis mechanismsProtein Structure and Dynamics

Cited by 153

Horizontal gene transfer: essentiality and evolvability in prokaryotes, and roles in evolutionary transitions

Koonin, E. V. (2016) · F1000Research

Genomics and Phylogenetic StudiesProtist diversity and phylogeny

Cited by 152

Trends in protein evolution inferred from sequence and structure analysis

Aravind, L., Mazumder, R., Vasudevan, S., & Koonin, E. V. (2002) · Current Opinion in Structural Biology

Protein Structure and DynamicsGenomics and Phylogenetic Studies

Cited by 148

Origin of eukaryotes from within archaea, archaeal eukaryome and bursts of gene gain: eukaryogenesis just made easier?

Koonin, E. V. (2015) · Philosophical Transactions of the Royal Society B: Biological Sciences

Protist diversity and phylogenyOrigins and Evolution of Life

Cited by 145