Rudolph, Uwe

Benzodiazepine actions mediated by specific γ-aminobutyric acidA receptor subtypes

Rudolph, U., Crestani, F., Benke, D., Brünig, I., Benson, J. A., Fritschy, J.-M., Martin, J. R., Bluethmann, H., & Möhler, H. (1999) · Nature

Neuroscience and Neuropharmacology ResearchNicotinic Acetylcholine Receptors Study

Cited by 1,172

Molecular and neuronal substrate for the selective attenuation of anxiety

Löw, K., Crestani, F., Keist, R., Benke, D., Brünig, I., Benson, J. A., Fritschy, J.-M., Rülicke, T., Bluethmann, H., Möhler, H., et al. (2000) · Science

Neuroscience and Neuropharmacology ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 946

Beyond classical benzodiazepines: novel therapeutic potential of GABAA receptor subtypes

Rudolph, U., & Knoflach, F. (2011) · Nature Reviews Drug Discovery

Neuroscience and Neuropharmacology ResearchNicotinic Acetylcholine Receptors Study

Cited by 733

A new benzodiazepine pharmacology

Möhler, H., Fritschy, J. M., & Rudolph, U. (2002) · The Journal of Pharmacology and Experimental Therapeutics

Neuroscience and Neuropharmacology ResearchSynthesis and pharmacology of benzodiazepine derivatives

Cited by 716

General anesthetic actions in vivo strongly attenuated by a point mutation in the GABA A receptor β3 subunit

Jurd, R., Arrasa, M., Lambert, S., Drexler, B., Siegwart, R., Crestani, F., Zaugg, M., Vogt, K. E., Ledermann, B., Antkowiak, B., et al. (2003) · The FASEB Journal

Anesthesia and Sedative AgentsNeuroscience and Neuropharmacology Research

Cited by 558

Trace fear conditioning involves hippocampal α 5 GABA A receptors

Crestani, F., Keist, R., Fritschy, J.-M., Benke, D., Vogt, K., Prut, L., Blüthmann, H., Möhler, H., & Rudolph, U. (2002) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 528

GABA-based therapeutic approaches: GABAA receptor subtype functions

RUDOLPH, U., & MOHLER, H. (2006) · Current Opinion in Pharmacology

Neuroscience and Neuropharmacology ResearchReceptor Mechanisms and Signaling

Cited by 499

Specific GABA A Circuits for Visual Cortical Plasticity

Fagiolini, M., Fritschy, J.-M., Löw, K., Möhler, H., Rudolph, U., & Hensch, T. K. (2004) · Science

Neuroscience and Neuropharmacology ResearchVisual perception and processing mechanisms

Cited by 471

Reversal of pathological pain through specific spinal GABAA receptor subtypes

Knabl, J., Witschi, R., Hösl, K., Reinold, H., Zeilhofer, U. B., Ahmadi, S., Brockhaus, J., Sergejeva, M., Hess, A., Brune, K., et al. (2008) · Nature

Pain Mechanisms and TreatmentsNeuroscience and Neuropharmacology Research

Cited by 438

Neural bases for addictive properties of benzodiazepines

Tan, K. R., Brown, M., Labouèbe, G., Yvon, C., Creton, C., Fritschy, J.-M., Rudolph, U., & Lüscher, C. (2010) · Nature

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 397

GABA A Receptor Subtypes: Therapeutic Potential in Down Syndrome, Affective Disorders, Schizophrenia, and Autism

Rudolph, U., & Möhler, H. (2014) · Annual Review of Pharmacology and Toxicology

Neuroscience and Neuropharmacology ResearchReceptor Mechanisms and Signaling

Cited by 319

An emerging circuit pharmacology of GABAA receptors

Engin, E., Benham, R. S., & Rudolph, U. (2018) · Trends in Pharmacological Sciences

Neuroscience and Neuropharmacology ResearchNicotinic Acetylcholine Receptors Study

Cited by 225

A schizophrenia-related sensorimotor deficit links α3-containing GABA A receptors to a dopamine hyperfunction

Yee, B. K., Keist, R., von Boehmer, L., Studer, R., Benke, D., Hagenbuch, N., Dong, Y., Malenka, R. C., Fritschy, J.-M., Bluethmann, H., et al. (2005) · Proceedings of the National Academy of Sciences

Schizophrenia research and treatmentNeuroscience and Neuropharmacology Research

Cited by 201

Regulating anxiety with extrasynaptic inhibition

Botta, P., Demmou, L., Kasugai, Y., Markovic, M., Xu, C., Fadok, J. P., Lu, T., Poe, M. M., Xu, L., Cook, J. M., et al. (2015) · Nature Neuroscience

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 192

Requirement of α5-GABAAReceptors for the Development of Tolerance to the Sedative Action of Diazepam in Mice

van Rijnsoever, C., Täuber, M., Choulli, M. K., Keist, R., Rudolph, U., Mohler, H., Fritschy, J. M., & Crestani, F. (2004) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchReceptor Mechanisms and Signaling

Cited by 144

Antidepressant-like properties of α2-containing GABAA receptors

Vollenweider, I., Smith, K. S., Keist, R., & Rudolph, U. (2011) · Behavioural Brain Research

Neuroscience and Neuropharmacology ResearchTreatment of Major Depression

Cited by 96

Benzodiazepine-induced anxiolysis and reduction of conditioned fear are mediated by distinct GABAA receptor subtypes in mice

Smith, K. S., Engin, E., Meloni, E. G., & Rudolph, U. (2012) · Neuropharmacology

Neuroscience and Neuropharmacology ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 94

Modulation of anxiety and fear via distinct intrahippocampal circuits

Engin, E., Smith, K. S., Gao, Y., Nagy, D., Foster, R. A., Tsvetkov, E., Keist, R., Crestani, F., Fritschy, J.-M., Bolshakov, V. Y., et al. (2016) · eLife

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 91

Tonic Inhibitory Control of Dentate Gyrus Granule Cells by α5-Containing GABAAReceptors Reduces Memory Interference

Engin, E., Zarnowska, E. D., Benke, D., Tsvetkov, E., Sigal, M., Keist, R., Bolshakov, V. Y., Pearce, R. A., & Rudolph, U. (2015) · The Journal of Neuroscience

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 79

Sleep EEG changes after zolpidem in mice

Kopp, C., Rudolph, U., & Tobler, I. (2004) · NeuroReport

Sleep and Wakefulness ResearchNeuroscience and Neuropharmacology Research

Cited by 66

Diazepam‐induced adaptive plasticity revealed by α1 GABAA receptor‐specific expression profiling

Huopaniemi, L., Keist, R., Randolph, A., Certa, U., & Rudolph, U. (2004) · Journal of Neurochemistry

Neuroscience and Neuropharmacology ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 58

A Pharmacogenetic ‘Restriction-of-Function’ Approach Reveals Evidence for Anxiolytic-Like Actions Mediated by α5-Containing GABAA Receptors in Mice

Behlke, L. M., Foster, R. A., Liu, J., Benke, D., Benham, R. S., Nathanson, A. J., Yee, B. K., Zeilhofer, H. U., Engin, E., & Rudolph, U. (2016) · Neuropsychopharmacology

Neuroscience and Neuropharmacology ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 57

Differential roles of GABAA receptor subtypes in benzodiazepine-induced enhancement of brain-stimulation reward

Reynolds, L. M., Engin, E., Tantillo, G., Lau, H. M., Muschamp, J. W., Carlezon, W. A., & Rudolph, U. (2012) · Neuropsychopharmacology

Neuroscience and Neuropharmacology ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 49

Hippocampal α5 subunit-containing GABAA receptors are involved in the development of the latent inhibition effect

Gerdjikov, T. V., Rudolph, U., Keist, R., Möhler, H., Feldon, J., & Yee, B. K. (2008) · Neurobiology of Learning and Memory

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 43