Nuutila, Pirjo

Functional Brown Adipose Tissue in Healthy Adults

Virtanen, K. A., Lidell, M. E., Orava, J., Heglind, M., Westergren, R., Niemi, T., Taittonen, M., Laine, J., Savisto, N.-J., Enerbäck, S., et al. (2009) · New England Journal of Medicine

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 3,058

Effect of Laparoscopic Sleeve Gastrectomy vs Laparoscopic Roux-en-Y Gastric Bypass on Weight Loss at 5 Years Among Patients With Morbid Obesity: The SLEEVEPASS Randomized Clinical Trial

Salminen, P., Helmiö, M., Ovaska, J., Juuti, A., Leivonen, M., Peromaa-Haavisto, P., Hurme, S., Soinio, M., Nuutila, P., & Victorzon, M. (2018) · JAMA

Bariatric Surgery and OutcomesMinimally Invasive Surgical Techniques

Cited by 946

Exercise Training Modulates Gut Microbiota Profile and Improves Endotoxemia

MOTIANI, K. K., COLLADO, M. C., ESKELINEN, J.-J., VIRTANEN, K. A., LÖYTTYNIEMI, E., SALMINEN, S., NUUTILA, P., KALLIOKOSKI, K. K., & HANNUKAINEN, J. C. (2020) · Medicine & Science in Sports & Exercise

Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases

Cited by 333

A Prospective Diagnostic Accuracy Study of 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography, Multidetector Row Computed Tomography, and Magnetic Resonance Imaging in Primary Diagnosis and Staging of Pancreatic Cancer

Kauhanen, S. P., Komar, G., Seppänen, M. P., Dean, K. I., Minn, H. R., Kajander, S. A., Rinta-Kiikka, I., Alanen, K., Borra, R. J., Puolakkainen, P. A., et al. (2009) · Annals of Surgery

Pancreatic and Hepatic Oncology ResearchMedical Imaging Techniques and Applications

Cited by 317

Glucose Uptake and Perfusion in Subcutaneous and Visceral Adipose Tissue during Insulin Stimulation in Nonobese and Obese Humans

Virtanen, K. A., Lönnroth, P., Parkkola, R., Peltoniemi, P., Asola, M., Viljanen, T., Tolvanen, T., Knuuti, J., Rönnemaa, T., Huupponen, R., et al. (2002) · The Journal of Clinical Endocrinology & Metabolism

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 315

The SGLT2 inhibitor dapagliflozin reduces liver fat but does not affect tissue insulin sensitivity: a randomized, double-blind, placebo-controlled study with 8-week treatment in type 2 diabetes patients

Latva-Rasku, A., Honka, M.-J., Kullberg, J., Mononen, N., Lehtimäki, T., Saltevo, J., Kirjavainen, A. K., Saunavaara, V., Iozzo, P., Johansson, L., et al. (2019) · Diabetes Care

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 253

Gender and Insulin Sensitivity in the Heart and in Skeletal Muscles: Studies Using Positron Emission Tomography

Nuutila, P., Knuuti, M. J., Mäki, M., Laine, H., Ruotsalainen, U., Teräs, M., Haaparanta, M., Solin, O., & Yki-Järvinen, H. (1995) · Diabetes

Diabetes, Cardiovascular Risks, and LipoproteinsMetabolism, Diabetes, and Cancer

Cited by 253

Secretin-Activated Brown Fat Mediates Prandial Thermogenesis to Induce Satiation

Li, Y., Schnabl, K., Gabler, S.-M., Willershäuser, M., Reber, J., Karlas, A., Laurila, S., Lahesmaa, M., u Din, M., Bast-Habersbrunner, A., et al. (2018) · Cell

Adipose Tissue and MetabolismRegulation of Appetite and Obesity

Cited by 228

Dorsal Striatum and Its Limbic Connectivity Mediate Abnormal Anticipatory Reward Processing in Obesity

Nummenmaa, L., Hirvonen, J., Hannukainen, J. C., Immonen, H., Lindroos, M. M., Salminen, P., & Nuutila, P. (2012) · PLoS ONE

Neural and Behavioral Psychology StudiesNeurotransmitter Receptor Influence on Behavior

Cited by 220

TGF-β2 is an exercise-induced adipokine that regulates glucose and fatty acid metabolism

Takahashi, H., Alves, C. R. R., Stanford, K. I., Middelbeek, R. J. W., Nigro, P., Ryan, R. E., Xue, R., Sakaguchi, M., Lynes, M. D., So, K., et al. (2019) · Nature Metabolism

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 204

Postprandial Oxidative Metabolism of Human Brown Fat Indicates Thermogenesis

U Din, M., Saari, T., Raiko, J., Kudomi, N., Maurer, S. F., Lahesmaa, M., Fromme, T., Amri, E.-Z., Klingenspor, M., Solin, O., et al. (2018) · Cell Metabolism

Adipose Tissue and MetabolismLipid metabolism and biosynthesis

Cited by 196

High intensity exercise decreases global brain glucose uptake in humans.

Kemppainen, J., Aalto, S., Fujimoto, T., Kalliokoski, K. K., Långsjö, J., Oikonen, V., Rinne, J., Nuutila, P., & Knuuti, J. (2005) · The Journal of Physiology

Cardiovascular and exercise physiologyPhysical Activity and Health

Cited by 179

Exercise training decreases pancreatic fat content and improves beta cell function regardless of baseline glucose tolerance: a randomised controlled trial

Heiskanen, M. A., Motiani, K. K., Mari, A., Saunavaara, V., Eskelinen, J.-J., Virtanen, K. A., Koivumäki, M., Löyttyniemi, E., Nuutila, P., Kalliokoski, K. K., et al. (2018) · Diabetologia

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 142

Insulin-stimulated glucose uptake in skeletal muscle, adipose tissue and liver: a positron emission tomography study

Honka, M.-J., Latva-Rasku, A., Bucci, M., Virtanen, K. A., Hannukainen, J. C., Kalliokoski, K. K., & Nuutila, P. (2018) · European Journal of Endocrinology

Diabetes, Cardiovascular Risks, and LipoproteinsDiet, Metabolism, and Disease

Cited by 140

Brain White Matter Expansion in Human Obesity and the Recovering Effect of Dieting

Haltia, L. T., Viljanen, A., Parkkola, R., Kemppainen, N., Rinne, J. O., Nuutila, P., & Kaasinen, V. (2007) · The Journal of Clinical Endocrinology & Metabolism

Advanced Neuroimaging Techniques and ApplicationsRegulation of Appetite and Obesity

Cited by 139

Human brown adipose tissue is phenocopied by classical brown adipose tissue in physiologically humanized mice

de Jong, J. M. A., Sun, W., Pires, N. D., Frontini, A., Balaz, M., Jespersen, N. Z., Feizi, A., Petrovic, K., Fischer, A. W., Bokhari, M. H., et al. (2019) · Nature Metabolism

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 137

Adult attachment style is associated with cerebral μ‐opioid receptor availability in humans

Nummenmaa, L., Manninen, S., Tuominen, L., Hirvonen, J., Kalliokoski, K. K., Nuutila, P., Jääskeläinen, I. P., Hari, R., Dunbar, R. I. M., & Sams, M. (2015) · Human Brain Mapping

Neuroendocrine regulation and behaviorAttachment and Relationship Dynamics

Cited by 133

Brain glucose metabolism in health, obesity, and cognitive decline-does insulin have anything to do with it? A narrative review

Rebelos, E., Rinne, J. O., Nuutila, P., & Ekblad, L. L. (2021) · Journal of Clinical Medicine

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 66

Exercise training improves adipose tissue metabolism and vasculature regardless of baseline glucose tolerance and sex.

Honkala, S. M., Motiani, P., Kivelä, R., Hemanthakumar, K. A., Tolvanen, E., Motiani, K. K., Eskelinen, J.-J., Virtanen, K. A., Kemppainen, J., Heiskanen, M. A., et al. (2020) · BMJ Open Diabetes Research & Care

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 37

Binge eating disorder and morbid obesity are associated with lowered mu-opioid receptor availability in the brain

Joutsa, J., Karlsson, H. K., Majuri, J., Nuutila, P., Helin, S., Kaasinen, V., & Nummenmaa, L. (2018) · Psychiatry Research Neuroimaging

Eating Disorders and BehaviorsRegulation of Appetite and Obesity

Cited by 35

Liver uptake of free fatty acids in vivo in humans as determined with 14( R , S )-[ 18 F]fluoro-6-thia-heptadecanoic acid and PET

Iozzo, P., Turpeinen, A. K., Takala, T., Oikonen, V., Solin, O., Ferrannini, E., Nuutila, P., & Knuuti, J. (2003) · European Journal of Nuclear Medicine and Molecular Imaging

Medical Imaging Techniques and ApplicationsLiver Disease Diagnosis and Treatment

Cited by 30

F-18 fluorodeoxyglucose uptake and water-perfusable tissue fraction in assessment of myocardial viability.

Iida, H., Ruotsalainen, U., Mäki, M., Haaparnata, M., Bergman, J., Voipio-Pulkki, L.-M., Nuutila, P., Koshino, K., & Knuuti, J. (2012) · Annals of Nuclear Medicine

Cardiac Imaging and DiagnosticsMedical Imaging Techniques and Applications

Cited by 15