Nave, Klaus-Armin

Multiple Sclerosis: An Immune or Neurodegenerative Disorder?

Trapp, B. D., & Nave, K.-A. (2008) · Annual Review of Neuroscience

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 1,724

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

Fünfschilling, U., Supplie, L. M., Mahad, D., Boretius, S., Saab, A. S., Edgar, J., Brinkmann, B. G., Kassmann, C. M., Tzvetanova, I. D., Möbius, W., et al. (2012) · Nature

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 1,523

Myelination and support of axonal integrity by glia

Nave, K.-A. (2010) · Nature

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 1,062

Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination

Lappe-Siefke, C., Goebbels, S., Gravel, M., Nicksch, E., Lee, J., Braun, P. E., Griffiths, I. R., & Nave, K.-A. (2003) · Nature Genetics

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 1,036

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

Cunnane, S. C., Trushina, E., Morland, C., Prigione, A., Casadesus, G., Andrews, Z. B., Beal, M. F., Bergersen, L. H., Brinton, R. D., de la Monte, S., et al. (2020) · Nature Reviews Drug Discovery

Mitochondrial Function and PathologyAlzheimer's disease research and treatments

Cited by 1,003

New Horizons in Diabetic Neuropathy: Mechanisms, Bioenergetics, and Pain

Feldman, E. L., Nave, K.-A., Jensen, T. S., & Bennett, D. L. H. (2017) · Neuron

Pain Mechanisms and TreatmentsPeripheral Neuropathies and Disorders

Cited by 915

Neurotransmitter-Triggered Transfer of Exosomes Mediates Oligodendrocyte–Neuron Communication

Frühbeis, C., Fröhlich, D., Kuo, W. P., Amphornrat, J., Thilemann, S., Saab, A. S., Kirchhoff, F., Möbius, W., Goebbels, S., Nave, K.-A., et al. (2013) · PLoS Biology

Extracellular vesicles in diseaseCellular transport and secretion

Cited by 902

Axonal Swellings and Degeneration in Mice Lacking the Major Proteolipid of Myelin

Griffiths, I., Klugmann, M., Anderson, T., Yool, D., Thomson, C., Schwab, M. H., Schneider, A., Zimmermann, F., McCulloch, M., Nadon, N., et al. (1998) · Science

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 889

High cholesterol level is essential for myelin membrane growth

Saher, G., Brügger, B., Lappe-Siefke, C., Möbius, W., Tozawa, R.-I., Wehr, M. C., Wieland, F., Ishibashi, S., & Nave, K.-A. (2005) · Nature Neuroscience

Neurogenesis and neuroplasticity mechanismsCholesterol and Lipid Metabolism

Cited by 799

The Endocannabinoid System Controls Key Epileptogenic Circuits in the Hippocampus

Monory, K., Massa, F., Egertová, M., Eder, M., Blaudzun, H., Westenbroek, R., Kelsch, W., Jacob, W., Marsch, R., Ekker, M., et al. (2006) · Neuron

Cannabis and Cannabinoid ResearchEpilepsy research and treatment

Cited by 706

Myelination and the trophic support of long axons

Nave, K.-A. (2010) · Nature Reviews Neuroscience

Nerve injury and regenerationNeuroinflammation and Neurodegeneration Mechanisms

Cited by 648

Neuroinflammation in Alzheimer disease

Heneka, M. T., van der Flier, W. M., Jessen, F., Hoozemanns, J., Thal, D. R., Boche, D., Brosseron, F., Teunissen, C., Zetterberg, H., Jacobs, A. H., et al. (2025) · Nature Reviews Immunology

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 638

Oligodendroglial NMDA receptors regulate glucose import and axonal energy metabolism

Saab, A. S., Tzvetavona, I. D., Trevisiol, A., Baltan, S., Dibaj, P., Kusch, K., Möbius, W., Goetze, B., Jahn, H. M., Huang, W., et al. (2016) · Neuron

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 590

Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease

Depp, C., Sun, T., Sasmita, A. O., Spieth, L., Berghoff, S. A., Nazarenko, T., Overhoff, K., Steixner-Kumar, A. A., Subramanian, S., Arinrad, S., et al. (2023) · Nature

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 493

Neurod1 is essential for the survival and maturation of adult-born neurons

Gao, Z., Ure, K., Ables, J. L., Lagace, D. C., Nave, K.-A., Goebbels, S., Eisch, A. J., & Hsieh, J. (2009) · Nature Neuroscience

Neurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology Research

Cited by 473

Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes

Kassmann, C. M., Lappe-Siefke, C., Baes, M., Brügger, B., Mildner, A., Werner, H. B., Natt, O., Michaelis, T., Prinz, M., Frahm, J., et al. (2007) · Nature Genetics

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 357

Neuropsychiatric disease relevance of circulating anti-NMDA receptor autoantibodies depends on blood–brain barrier integrity

Hammer, C., Stepniak, B., Schneider, A., Papiol, S., Tantra, M., Begemann, M., Sirén, A.-L., Pardo, L. A., Sperling, S., Mohd Jofrry, S., et al. (2014) · Molecular Psychiatry

Autoimmune Neurological Disorders and TreatmentsSystemic Lupus Erythematosus Research

Cited by 342

Lipid metabolism in myelinating glial cells: lessons from human inherited disorders and mouse models

Chrast, R., Saher, G., Nave, K.-A., & Verheijen, M. H. G. (2011) · Journal of Lipid Research

Lipid metabolism and biosynthesisSphingolipid Metabolism and Signaling

Cited by 314

Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis

Berghoff, S. A., Spieth, L., Sun, T., Hosang, L., Schlaphoff, L., Depp, C., Düking, T., Winchenbach, J., Neuber, J., Ewers, D., et al. (2021) · Nature Neuroscience

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 307

Oligodendroglial myelination requires astrocyte-derived lipids

Camargo, N., Goudriaan, A., van Deijk, A.-L. F., Otte, W. M., Brouwers, J. F., Lodder, H., Gutmann, D. H., Nave, K.-A., Dijkhuizen, R. M., Mansvelder, H. D., et al. (2017) · PLOS Biology

Neurogenesis and neuroplasticity mechanismsLipid metabolism and biosynthesis

Cited by 296

The Axon-Myelin Unit in Development and Degenerative Disease

Stassart, R. M., Möbius, W., Nave, K.-A., & Edgar, J. M. (2018) · Frontiers in Neuroscience

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 246

Glial Biology in Learning and Cognition

Fields, R. D., Araque, A., Johansen-Berg, H., Lim, S.-S., Lynch, G., Nave, K.-A., Nedergaard, M., Perez, R., Sejnowski, T., & Wake, H. (2014) · The Neuroscientist

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 232

Notch1 control of oligodendrocyte differentiation in the spinal cord

Genoud, S., Lappe-Siefke, C., Goebbels, S., Radtke, F., Aguet, M., Scherer, S. S., Suter, U., Nave, K.-A., & Mantei, N. (2002) · The Journal of Cell Biology

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 211

Pyramidal neurons of upper cortical layers generated by NEX-positive progenitor cells in the subventricular zone

Wu, S.-X., Goebbels, S., Nakamura, K., Nakamura, K., Kometani, K., Minato, N., Kaneko, T., Nave, K.-A., & Tamamaki, N. (2005) · Proceedings of the National Academy of Sciences

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 198