Johnson, Rodney W.

From inflammation to sickness and depression: when the immune system subjugates the brain

Dantzer, R., O'Connor, J. C., Freund, G. G., Johnson, R. W., & Kelley, K. W. (2008) · Nature Reviews Neuroscience

Tryptophan and brain disordersStress Responses and Cortisol

Cited by 7,395

Exaggerated neuroinflammation and sickness behavior in aged mice after activation of the peripheral innate immune system

Godbout, J. P., Chen, J., Abraham, J., Richwine, A. F., Berg, B. M., Kelley, K. W., & Johnson, R. W. (2005) · The FASEB Journal

Neuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders

Cited by 813

Cytokine-induced sickness behavior

Kelley, K. W., Bluthé, R.-M., Dantzer, R., Zhou, J.-H., Shen, W.-H., Johnson, R. W., & Broussard, S. R. (2003) · Brain, Behavior, and Immunity

Tryptophan and brain disordersStress Responses and Cortisol

Cited by 716

Butyrate and Dietary Soluble Fiber Improve Neuroinflammation Associated With Aging in Mice

Matt, S. M., Allen, J. M., Lawson, M. A., Mailing, L. J., Woods, J. A., & Johnson, R. W. (2018) · Frontiers in Immunology

Neuroinflammation and Neurodegeneration MechanismsGut microbiota and health

Cited by 330

Perinatal iron deficiency and neurocognitive development

Radlowski, E. C., & Johnson, R. W. (2013) · Frontiers in Human Neuroscience

Iron Metabolism and DisordersTrace Elements in Health

Cited by 315

Interleukin-6 Facilitates Lipopolysaccharide-Induced Disruption in Working Memory and Expression of Other Proinflammatory Cytokines in Hippocampal Neuronal Cell Layers

Sparkman, N. L., Buchanan, J. B., Heyen, J. R. R., Chen, J., Beverly, J. L., & Johnson, R. W. (2006) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders

Cited by 307

Aging Exacerbates Depressive-like Behavior in Mice in Response to Activation of the Peripheral Innate Immune System

Godbout, J. P., Moreau, M., Lestage, J., Chen, J., Sparkman, N. L., Connor, J. O., Castanon, N., Kelley, K. W., Dantzer, R., & Johnson, R. W. (2008) · Neuropsychopharmacology

Tryptophan and brain disordersStress Responses and Cortisol

Cited by 299

Influenza Infection Induces Neuroinflammation, Alters Hippocampal Neuron Morphology, and Impairs Cognition in Adult Mice

Jurgens, H. A., Amancherla, K., & Johnson, R. W. (2012) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsInfectious Encephalopathies and Encephalitis

Cited by 243

Regulation of IGF-I function by proinflammatory cytokines: At the interface of immunology and endocrinology

O’Connor, J. C., McCusker, R. H., Strle, K., Johnson, R. W., Dantzer, R., & Kelley, K. W. (2008) · Cellular Immunology

Growth Hormone and Insulin-like Growth FactorsCytokine Signaling Pathways and Interactions

Cited by 238

Inhibition of inflammatory microglia by dietary fiber and short-chain fatty acids

Caetano-Silva, M. E., Rund, L., Hutchinson, N. T., Woods, J. A., Steelman, A. J., & Johnson, R. W. (2023) · Scientific Reports

Neuroinflammation and Neurodegeneration MechanismsGut microbiota and health

Cited by 225

Age and neuroinflammation: a lifetime of psychoneuroimmune consequences

Godbout, J. P., & Johnson, R. W. (2009) · Immunology and Allergy Clinics of North America

Neuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders

Cited by 224

An Age-Related Decline in Interleukin-10 May Contribute to the Increased Expression of Interleukin-6 in Brain of Aged Mice

Ye, S.-M., & Johnson, R. W. (2001) · Neuroimmunomodulation

Neuroinflammation and Neurodegeneration MechanismsNF-κB Signaling Pathways

Cited by 203

Dysregulated neuronal–microglial cross-talk during aging, stress and inflammation

Jurgens, H. A., & Johnson, R. W. (2012) · Experimental Neurology

Neuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders

Cited by 179

Interleukin (IL)-10 inhibits IL-6 production in microglia by preventing activation of NF-κB

Heyen, J. R. R., Ye, S.-M., Finck, B. N., & Johnson, R. W. (2000) · Molecular Brain Research

NF-κB Signaling PathwaysNeuroinflammation and Neurodegeneration Mechanisms

Cited by 146

Consuming a diet supplemented with resveratrol reduced infection-related neuroinflammation and deficits in working memory in aged mice

Abraham, J., & Johnson, R. W. (2009) · Rejuvenation Research

Sirtuins and Resveratrol in MedicineNeuroinflammation and Neurodegeneration Mechanisms

Cited by 131

IL-1β-Mediated Innate Immunity Is Amplified in the db/db Mouse Model of Type 2 Diabetes

O’Connor, J. C., Satpathy, A., Hartman, M. E., Horvath, E. M., Kelley, K. W., Dantzer, R., Johnson, R. W., & Freund, G. G. (2005) · The Journal of Immunology

Adipokines, Inflammation, and Metabolic DiseasesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 86

Dietary Luteolin Reduces Proinflammatory Microglia in the Brain of Senescent Mice

Burton, M. D., Rytych, J. L., Amin, R., & Johnson, R. W. (2016) · Rejuvenation Research

Neuroinflammation and Neurodegeneration MechanismsFlavonoids in Medical Research

Cited by 69

Novel activity of an anti-inflammatory cytokine: IL-10 prevents TNFα-induced resistance to IGF-I in myoblasts

Strle, K., McCusker, R. H., Tran, L., King, A., Johnson, R. W., Freund, G. G., Dantzer, R., & Kelley, K. W. (2007) · Journal of Neuroimmunology

Muscle Physiology and DisordersCytokine Signaling Pathways and Interactions

Cited by 43

A neurotoxic regimen of methamphetamine exacerbates the febrile and neuroinflammatory response to a subsequent peripheral immune stimulus

Buchanan, J. B., Sparkman, N. L., & Johnson, R. W. (2010) · Journal of Neuroinflammation

Neuroinflammation and Neurodegeneration MechanismsThermal Regulation in Medicine

Cited by 35

Prototypical anti-inflammatory cytokine IL-10 prevents loss of IGF-I-induced myogenin protein expression caused by IL-1β

Strle, K., McCusker, R. H., Johnson, R. W., Zunich, S. M., Dantzer, R., & Kelley, K. W. (2008) · American Journal of Physiology-Endocrinology and Metabolism

Cytokine Signaling Pathways and InteractionsMuscle Physiology and Disorders

Cited by 32