Dysregulated neuronal–microglial cross-talk during aging, stress and inflammation

Pathogen Recognition and Innate Immunity

Akira, S., Uematsu, S., & Takeuchi, O. (2006) · Cell · doi:10.1016/j.cell.2006.02.015 · Cited by 11,974 · see citing works

From inflammation to sickness and depression: when the immune system subjugates the brain

Dantzer, R., O'Connor, J. C., Freund, G. G., Johnson, R. W., & Kelley, K. W. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2297 · Cited by 7,395 · see citing works

Effects of stress throughout the lifespan on the brain, behaviour and cognition

Lupien, S. J., McEwen, B. S., Gunnar, M. R., & Heim, C. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2639 · Cited by 6,256 · see citing works

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

Nimmerjahn, A., Kirchhoff, F., & Helmchen, F. (2005) · Science · doi:10.1126/science.1110647 · Cited by 5,827 · see citing works

Microglia: a sensor for pathological events in the CNS

Kreutzberg, G. W. (1996) · Trends in Neurosciences · doi:10.1016/0166-2236(96)10049-7 · Cited by 4,396 · see citing works

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

Block, M. L., Zecca, L., & Hong, J.-S. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2038 · Cited by 4,110 · see citing works

ATP mediates rapid microglial response to local brain injury in vivo

Davalos, D., Grutzendler, J., Yang, G., Kim, J. V., Zuo, Y., Jung, S., Littman, D. R., Dustin, M. L., & Gan, W.-B. (2005) · Nature Neuroscience · doi:10.1038/nn1472 · Cited by 3,913 · see citing works

Microglia: Active sensor and versatile effector cells in the normal and pathologic brain

Hanisch, U.-K., & Kettenmann, H. (2007) · Nature Neuroscience · doi:10.1038/nn1997 · Cited by 3,676 · see citing works

Neurotrophins and their receptors: A convergence point for many signalling pathways

Chao, M. V. (2003) · Nature Reviews Neuroscience · doi:10.1038/nrn1078 · Cited by 2,298 · see citing works

Biological basis of the behavior of sick animals

Hart, B. L. (1988) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(88)80004-6 · Cited by 2,223 · see citing works

Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain

Lawson, L. J., Perry, V. H., Dri, P., & Gordon, S. (1990) · Neuroscience · doi:10.1016/0306-4522(90)90229-w · Cited by 2,045 · see citing works

A new class of membrane-bound chemokine with a CX3C motif

Bazan, J. F., Bacon, K. B., Hardiman, G., Wang, W., Soo, K., Rossi, D., Greaves, D. R., Zlotnik, A., & Schall, T. J. (1997) · Nature · doi:10.1038/385640a0 · Cited by 2,013 · see citing works

Microglial physiology: unique stimuli, specialized responses

Ransohoff, R. M., & Perry, V. H. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132528 · Cited by 1,858 · see citing works

Neurotrophins as synaptic modulators

Poo, M.-M. (2001) · Nature Reviews Neuroscience · doi:10.1038/35049004 · Cited by 1,775 · see citing works

Microglia as a source and target of cytokines

Hanisch, U. (2002) · Glia · doi:10.1002/glia.10161 · Cited by 1,645 · cited 1× · see citing works

Resting Microglia Directly Monitor the Functional State of Synapses <i>In Vivo</i> and Determine the Fate of Ischemic Terminals

Wake, H., Moorhouse, A. J., Jinno, S., Kohsaka, S., & Nabekura, J. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.4363-08.2009 · Cited by 1,619 · see citing works

Control of microglial neurotoxicity by the fractalkine receptor

Cardona, A. E., Pioro, E. P., Sasse, M. E., Kostenko, V., Cardona, S. M., Dijkstra, I. M., Huang, D., Kidd, G., Dombrowski, S., Dutta, R., et al. (2006) · Nature Neuroscience · doi:10.1038/nn1715 · Cited by 1,531 · see citing works

Twenty years of research on cytokine-induced sickness behavior

Dantzer, R., & Kelley, K. W. (2007) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2006.09.006 · Cited by 1,420 · see citing works

The Mystery and Magic of Glia: A Perspective on Their Roles in Health and Disease

Barres, B. A. (2008) · Neuron · doi:10.1016/j.neuron.2008.10.013 · Cited by 1,352 · see citing works

Neural mechanisms of ageing and cognitive decline

Bishop, N. A., Lu, T., & Yankner, B. A. (2010) · Nature · doi:10.1038/nature08983 · Cited by 1,323 · see citing works

Role for Neuronally Derived Fractalkine in Mediating Interactions between Neurons and CX3CR1-Expressing Microglia

Harrison, J. K., Jiang, Y., Chen, S., Xia, Y., Maciejewski, D., McNamara, R. K., Streit, W. J., Salafranca, M. N., Adhikari, S., Thompson, D. A., et al. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.18.10896 · Cited by 1,176 · see citing works

Cytokines for psychologists: Implications of bidirectional immune-to-brain communication for understanding behavior, mood, and cognition.

Maier, S. F., & Watkins, L. R. (1998) · Psychological Review · doi:10.1037/0033-295x.105.1.83 · Cited by 1,130 · see citing works

Debris clearance by microglia: an essential link between degeneration and regeneration

Neumann, H., Kotter, M. R., & Franklin, R. J. M. (2008) · Brain · doi:10.1093/brain/awn109 · Cited by 1,111 · see citing works

Ageing and neuronal vulnerability

Mattson, M. P., & Magnus, T. (2006) · Nature reviews. Neuroscience · doi:10.1038/nrn1886 · Cited by 1,075 · see citing works

Gene-expression profile of the ageing brain in mice

Lee, C.-K., Weindruch, R., & Prolla, T. A. (2000) · Nature Genetics · doi:10.1038/77046 · Cited by 1,055 · see citing works

Systemic infections and inflammation affect chronic neurodegeneration

Perry, V. H., Cunningham, C., & Holmes, C. (2007) · Nature Reviews Immunology · doi:10.1038/nri2015 · Cited by 1,027 · see citing works

Down-Regulation of the Macrophage Lineage Through Interaction with OX2 (CD200)

Hoek, R. M., Ruuls, S. R., Murphy, C. A., Wright, G. J., Goddard, R., Zurawski, S. M., Blom, B., Homola, M. E., Streit, W. J., Brown, M. H., et al. (2000) · Science · doi:10.1126/science.290.5497.1768 · Cited by 1,022 · see citing works

Microglia as neuroprotective, immunocompetent cells of the CNS

Streit, W. J. (2002) · Glia · doi:10.1002/glia.10154 · Cited by 919 · see citing works

Enhancing versus Suppressive Effects of Stress on Immune Function: Implications for Immunoprotection and Immunopathology

Dhabhar, F. S. (2009) · Neuroimmunomodulation · doi:10.1159/000216188 · Cited by 903 · see citing works

Cytokine-induced sickness behavior: where do we stand?

Dantzer, R. (2001) · Brain, Behavior, and Immunity · doi:10.1006/brbi.2000.0613 · Cited by 862 · see citing works

Exaggerated neuroinflammation and sickness behavior in aged mice after activation of the peripheral innate immune system

Godbout, J. P., Chen, J., Abraham, J., Richwine, A. F., Berg, B. M., Kelley, K. W., & Johnson, R. W. (2005) · The FASEB Journal · doi:10.1096/fj.05-3776fje · Cited by 813 · see citing works

Neuronal ‘On’ and ‘Off’ signals control microglia

Biber, K., Neumann, H., Inoue, K., & Boddeke, H. W. G. M. (2007) · Trends in Neurosciences · doi:10.1016/j.tins.2007.08.007 · Cited by 787 · see citing works

Central and Systemic Endotoxin Challenges Exacerbate the Local Inflammatory Response and Increase Neuronal Death during Chronic Neurodegeneration

Cunningham, C., Wilcockson, D. C., Campion, S., Lunnon, K., & Perry, V. H. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.2614-05.2005 · Cited by 768 · see citing works

What is immune privilege (not)?

Galea, I., Bechmann, I., & Perry, V. H. (2007) · Trends in Immunology · doi:10.1016/j.it.2006.11.004 · Cited by 768 · see citing works

Macrophages and microglia in the nervous system

Perry, V. H., & Gordon, S. (1988) · Trends in Neurosciences · doi:10.1016/0166-2236(88)90110-5 · Cited by 747 · see citing works

Microglia: biology and pathology

Graeber, M., & Streit, W. (2009) · Acta Neuropathologica · doi:10.1007/s00401-009-0622-0 · Cited by 729 · see citing works

Cytokine-induced sickness behavior

Kelley, K. W., Bluthé, R.-M., Dantzer, R., Zhou, J.-H., Shen, W.-H., Johnson, R. W., & Broussard, S. R. (2003) · Brain, Behavior, and Immunity · doi:10.1016/s0889-1591(02)00077-6 · Cited by 716 · see citing works

Immune activation in brain aging and neurodegeneration: too much or too little?

Lucin, K. M., & Wyss-Coray, T. (2009) · Neuron · doi:10.1016/j.neuron.2009.08.039 · Cited by 679 · see citing works

From Acquisition to Consolidation: On the Role of Brain-Derived Neurotrophic Factor Signaling in Hippocampal-Dependent LearningPreprint

Tyler, W. J., Alonso, M., Bramham, C. R., & Pozzo‐Miller, L. D. (2002) · Learning & Memory · doi:10.1101/lm.51202 · Cited by 679 · see citing works

Neurotransmitter receptors on microglia

Pocock, J. M., & Kettenmann, H. (2007) · Trends in Neurosciences · doi:10.1016/j.tins.2007.07.007 · Cited by 650 · see citing works

Neurotactin, a membrane-anchored chemokine upregulated in brain inflammation

Pan, Y., Lloyd, C. M., Zhou, H., Dolich, S., Deeds, J., Gonzalo, J.-Á., Vath, J., Gosselin, M., Ma, J., Dussault, B. J., et al. (1997) · Nature · doi:10.1038/42491 · Cited by 643 · see citing works

Cytokines and cognition–the case for a head-to-toe inflammatory paradigm.

Wilson, C. J., Finch, C. E., & Cohen, H. J. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50619.x · Cited by 637 · see citing works

Microglia serve as a neuroimmune substrate for stress-induced potentiation of CNS pro-inflammatory cytokine responses

Frank, M. G., Baratta, M. V., Sprunger, D. B., Watkins, L. R., & Maier, S. F. (2007) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2006.03.005 · Cited by 578 · see citing works

New insights into brain BDNF function in normal aging and Alzheimer disease

Tapia‐Arancibia, L., Aliaga, E., Silhol, M., & Arancibia, S. (2008) · Brain Research Reviews · doi:10.1016/j.brainresrev.2008.07.007 · Cited by 571 · see citing works

Gene Microarrays in Hippocampal Aging: Statistical Profiling Identifies Novel Processes Correlated with Cognitive Impairment

Blalock, E. M., Chen, K.-C., Sharrow, K., Herman, J. P., Porter, N. M., Foster, T. C., & Landfield, P. W. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-09-03807.2003 · Cited by 570 · see citing works

Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1β and anti-inflammatory IL-10 cytokines

Henry, C. J., Huang, Y., Wynne, A. M., & Godbout, J. P. (2009) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2008.09.002 · Cited by 565 · see citing works

BDNF in schizophrenia, depression and corresponding animal models

Angelucci, F., Brené, S., & Mathé, A. A. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001637 · Cited by 548 · see citing works

Chronic stress alters the density and morphology of microglia in a subset of stress-responsive brain regions

Tynan, R. J., Naicker, S., Hinwood, M., Nalivaiko, E., Buller, K. M., Pow, D. V., Day, T. A., & Walker, F. R. (2010) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2010.02.001 · Cited by 531 · see citing works

Local distribution of microglia in the normal adult human central nervous system differs by up to one order of magnitude

Mittelbronn, M., Dietz, K., Schluesener, H. J., & Meyermann, R. (2001) · Acta Neuropathologica · doi:10.1007/s004010000284 · Cited by 482 · see citing works

An inflammatory review of glucocorticoid actions in the CNS

Sorrells, S. F., & Sapolsky, R. M. (2006) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2006.11.006 · Cited by 461 · see citing works

Characterization of the CD200 Receptor Family in Mice and Humans and Their Interactions with CD200

Wright, G. J., Cherwinski, H. M., Foster‐Cuevas, M., Brooke, G. P., Puklavec, M. J., Bigler, M., Song, Y., Jenmalm, M. C., Gorman, D., McClanahan, T., et al. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.6.3034 · Cited by 434 · see citing works

Microglial phenotype: is the commitment reversible?

Schwartz, M., Butovsky, O., Brück, W., & Hanisch, U.-K. (2006) · Trends in Neurosciences · doi:10.1016/j.tins.2005.12.005 · Cited by 434 · see citing works

The impact of systemic infection on the progression of neurodegenerative disease

Perry, V. H., Newman, T. A., & Cunningham, C. (2003) · Nature Reviews Neuroscience · doi:10.1038/nrn1032 · Cited by 428 · see citing works

The Stressed CNS: When Glucocorticoids Aggravate Inflammation

Sorrells, S. F., Caso, J. R., Munhoz, C. D., & Sapolsky, R. M. (2009) · Neuron · doi:10.1016/j.neuron.2009.09.032 · Cited by 425 · cited 2× · see citing works

CD200 and membrane protein interactions in the control of myeloid cells

Barclay, A. N., Wright, G. J., Brooke, G. P., & Brown, M. H. (2002) · Trends in Immunology · doi:10.1016/s1471-4906(02)02223-8 · Cited by 416 · see citing works

Interleukin-10 in the brain.

Strle, K., Zhou, J.-H., Shen, W. H., Broussard, S., Johnson, R. W., Freund, G., Dantzer, R., & Kelley, K. (2001) · Critical Reviews in Immunology · doi:10.1615/critrevimmunol.v21.i5.20 · Cited by 408 · see citing works

Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system

Chen, J., Buchanan, J. B., Sparkman, N. L., Godbout, J. P., Freund, G. G., & Johnson, R. W. (2007) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2007.08.014 · Cited by 396 · see citing works

Stress-induced elevation of glucocorticoids increases microglia proliferation through NMDA receptor activation

Nair, A., & Bonneau, R. H. (2006) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2005.09.012 · Cited by 392 · see citing works

Aging, microglial cell priming, and the discordant central inflammatory response to signals from the peripheral immune system

Dilger, R. N., & Johnson, R. W. (2008) · Journal of Leukocyte Biology · doi:10.1189/jlb.0208108 · Cited by 391 · see citing works

Altered antigen expression of microglia in the aged rodent CNS

Perry, V. H., Matyszak, M. K., & Fearn, S. (1993) · Glia · doi:10.1002/glia.440070111 · Cited by 364 · see citing works

Fractalkine and CX3CR1 regulate hippocampal neurogenesis in adult and aged rats

Bachstetter, A. D., Morganti, J. M., Jernberg, J., Schlunk, A., Mitchell, S. H., Brewster, K. W., Hudson, C. E., Cole, M. J., Harrison, J. K., Bickford, P. C., et al. (2011) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2009.11.022 · Cited by 364 · see citing works

An Innate Sense of Danger

Matzinger, P. (2002) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2002.tb03118.x · Cited by 360 · see citing works

Microglia in the Aging Brain

Conde, J. R., & Streit, W. J. (2006) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/01.jnen.0000202887.22082.63 · Cited by 344 · see citing works

Production and neuroprotective functions of fractalkine in the central nervous system

Mizuno, T., Kawanokuchi, J., Numata, K., & Suzumura, A. (2003) · Brain Research · doi:10.1016/s0006-8993(03)02867-1 · Cited by 336 · see citing works

Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function

Njie, E. G., Boelen, E., Stassen, F. R., Steinbusch, H. W. M., Borchelt, D. R., & Streit, W. J. (2012) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2010.05.008 · Cited by 335 · see citing works

Neuroinflammation Associated with Aging Sensitizes the Brain to the Effects of Infection or Stress

Sparkman, N. L., & Johnson, R. W. (2008) · NeuroImmunoModulation · doi:10.1159/000156474 · Cited by 330 · see citing works

Peripheral infection and aging interact to impair hippocampal memory consolidation

Barrientos, R. M., Higgins, E. A., Biedenkapp, J. C., Sprunger, D. B., Wright-Hardesty, K. J., Watkins, L. R., Rudy, J. W., & Maier, S. F. (2006) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.03.010 · Cited by 330 · see citing works

mRNA up-regulation of MHC II and pivotal pro-inflammatory genes in normal brain aging

Frank, M. G., Barrientos, R. M., Biedenkapp, J. C., Rudy, J. W., Watkins, L. R., & Maier, S. F. (2006) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.03.013 · Cited by 327 · see citing works

The Multifaceted Profile of Activated Microglia

Lynch, M. A. (2009) · Molecular Neurobiology · doi:10.1007/s12035-009-8077-9 · Cited by 323 · see citing works

Tumor Necrosis Factor Inhibits Neurite Outgrowth and Branching of Hippocampal Neurons by a Rho-Dependent Mechanism

Neumann, H., Schweigreiter, R., Yamashita, T., Rosenkranz, K., Wekerle, H., & Barde, Y. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-03-00854.2002 · Cited by 323 · see citing works

Control of glial immune function by neurons

Neumann, H. (2001) · Glia · doi:10.1002/glia.1108 · Cited by 319 · see citing works

Interleukin‐6: a cytokine to forget

Balschun, D., Wetzel, W., del Rey, A., Pitossi, F. J., Schneider, H., Zuschratter, W., & Besedovsky, H. O. (2004) · The FASEB Journal · doi:10.1096/fj.04-1625fje · Cited by 317 · see citing works

Cytokine signals propagate through the brain

Vitković, L., Konsman, J. P., Bockaert, J., Dantzer, R., Homburger, V., & Jacque, C. (2000) · Molecular Psychiatry · doi:10.1038/sj.mp.4000813 · Cited by 306 · see citing works

Prior exposure to glucocorticoids sensitizes the neuroinflammatory and peripheral inflammatory responses to E. coli lipopolysaccharide

Frank, M. G., Miguel, Z. D., Watkins, L. R., & Maier, S. F. (2010) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2009.07.008 · Cited by 303 · see citing works

Aging Exacerbates Depressive-like Behavior in Mice in Response to Activation of the Peripheral Innate Immune System

Godbout, J. P., Moreau, M., Lestage, J., Chen, J., Sparkman, N. L., Connor, J. O., Castanon, N., Kelley, K. W., Dantzer, R., & Johnson, R. W. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301649 · Cited by 299 · see citing works

The concept of sickness behavior: a brief chronological account of four key discoveries

Johnson, R. W. (2002) · Veterinary Immunology and Immunopathology · doi:10.1016/s0165-2427(02)00069-7 · Cited by 298 · see citing works

Cascading effects of stressors and inflammatory immune system activation: Implications for major depressive disorder

Anisman, H. (2009) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0902 · Cited by 292 · see citing works

Neurotrophins inhibit major histocompatibility class II inducibility of microglia: Involvement of the p75 neurotrophin receptor

Neumann, H., Misgeld, T., Matsumuro, K., & Wekerle, H. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.10.5779 · Cited by 282 · see citing works

Chronic Unpredictable Stress Exacerbates Lipopolysaccharide-Induced Activation of Nuclear Factor-κB in the Frontal Cortex and Hippocampus via Glucocorticoid Secretion

Munhoz, C. D., Lepsch, L. B., Kawamoto, E. M., Malta, M. B., Lima, L. D. S., Werneck Avellar, M. C., Sapolsky, R. M., & Scavone, C. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.4398-05.2006 · Cited by 274 · see citing works

Neuroinflammation and cognitive function in aged mice following minor surgery

Rosczyk, H. A., Sparkman, N. L., & Johnson, R. W. (2008) · Experimental Gerontology · doi:10.1016/j.exger.2008.06.004 · Cited by 271 · see citing works

Prior Stressor Exposure Sensitizes LPS-Induced Cytokine Production

Johnson, J. D., O'Connor, K. A., Deak, T., Stark, M., Watkins, L. R., & Maier, S. F. (2002) · Brain, Behavior, and Immunity · doi:10.1006/brbi.2001.0638 · Cited by 270 · see citing works

Decreased expression of CD200 and CD200 receptor in Alzheimer's disease: A potential mechanism leading to chronic inflammation

Walker, D. G., Dalsing-Hernandez, J. E., Campbell, N. A., & Lue, L. (2008) · Experimental Neurology · doi:10.1016/j.expneurol.2008.09.003 · Cited by 268 · see citing works

CD200 Ligand–Receptor Interaction Modulates Microglial Activation<i>In Vivo</i>and<i>In Vitro</i>: A Role for IL-4

Lyons, A., Downer, E. J., Crotty, S., Nolan, Y. M., Mills, K. H. G., & Lynch, M. A. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.1781-07.2007 · Cited by 258 · see citing works

Effects of Stress on Neurotrophic Factor Expression in the Rat Brain

SMITH, M. A., Makino, S., Květňanský, R., & Post, R. M. (1995) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1995.tb44684.x · Cited by 255 · see citing works

Brain-Derived Neurotrophic Factor MRNA Downregulation Produced by Social Isolation Is Blocked by Intrahippocampal Interleukin-1 Receptor Antagonist

Barrientos, R. M., Sprunger, D. B., Campeau, S., Higgins, E. A., Watkins, L. R., Rudy, J. W., & Maier, S. F. (2003) · Neuroscience · doi:10.1016/s0306-4522(03)00564-5 · Cited by 251 · see citing works

Peripheral immune activation by lipopolysaccharide decreases neurotrophins in the cortex and hippocampus in rats

Guan, Z., & Fang, J. (2006) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2005.04.005 · Cited by 247 · see citing works

Peripheral and central proinflammatory cytokine response to a severe acute stressor

O'Connor, K. A., Johnson, J. D., Hansen, M. K., Wieseler Frank, J. L., Maksimova, E., Watkins, L. R., & Maier, S. F. (2003) · Brain Research · doi:10.1016/j.brainres.2003.08.006 · Cited by 247 · see citing works

Microglial Expression of MHC Class II Increases in Normal Aging of Nonhuman Primates

Sheffield, L. G., & Berman, N. E. J. (1998) · Neurobiology of Aging · doi:10.1016/s0197-4580(97)00168-1 · Cited by 234 · see citing works

Temporal and spatial relationships between lipopolysaccharide-induced expression of fos, interleukin-1 β and inducible nitric oxide synthase in rat brain

Konsman, J. P., Kelley, K. W., & Dantzer, R. (1999) · Neuroscience · doi:10.1016/s0306-4522(98)00368-6 · Cited by 232 · see citing works

Entry of Blood-Borne Cytokines into the Central Nervous System: Effects on Cognitive Processes

Banks, W. A., Farr, S. A., & Morley, J. E. (2002) · NeuroImmunoModulation · doi:10.1159/000071472 · Cited by 228 · see citing works

Protracted downregulation of CX3CR1 on microglia of aged mice after lipopolysaccharide challenge

Wynne, A. M., Henry, C. J., Huang, Y., Cleland, A., & Godbout, J. P. (2010) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2010.05.011 · Cited by 224 · see citing works

Age and neuroinflammation: a lifetime of psychoneuroimmune consequences

Godbout, J. P., & Johnson, R. W. (2009) · Immunology and Allergy Clinics of North America · doi:10.1016/j.iac.2009.02.007 · Cited by 224 · see citing works

Interleukin‐10 Inhibits Both Production of Cytokines and Expression of Cytokine Receptors in Microglia

Sawada, M., Suzumura, A., Hosoya, H., Marunouchi, T., & Nagatsu, T. (1999) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1999.721466.x · Cited by 223 · see citing works

Interleukin-1β impairs brain derived neurotrophic factor-induced signal transduction

Tong, L., Balazs, R., Soiampornkul, R., Thangnipon, W., & Cotman, C. W. (2008) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2007.02.027 · Cited by 222 · see citing works

Exaggerated sickness behavior and brain proinflammatory cytokine expression in aged mice in response to intracerebroventricular lipopolysaccharide

Huang, Y., Henry, C. J., Dantzer, R., Johnson, R. W., & Godbout, J. P. (2007) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2007.04.012 · Cited by 218 · see citing works

Pro-inflammatory cytokines and their effects in the dentate gyrus

Pickering, M., & O’Connor, J. J. (2007) · Progress in Brain Research · doi:10.1016/s0079-6123(07)63020-9 · Cited by 217 · see citing works

Stress induced morphological microglial activation in the rodent brain: Involvement of interleukin-18

Sugama, S., Fujita, M., Hashimoto, M., & Conti, B. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.02.043 · Cited by 216 · see citing works

Stress increases vulnerability to inflammation in the rat prefrontal cortex

de Pablos, R. M., Villarán, R. F., Argüelles, S., Herrera, A. J., Venero, J. L., Ayala, A., Cano, J., & Machado, A. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.0802-06.2006 · Cited by 215 · see citing works

Role of Interleukin-4 in Regulation of Age-related Inflammatory Changes in the Hippocampus

Nolan, Y. M., Maher, F. O., Martin, D. S. D., Clarke, R. M., Brady, M. T., Bolton, A. E., Mills, K. H. G., & Lynch, M. A. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m412170200 · Cited by 210 · see citing works

An Age-Related Decline in Interleukin-10 May Contribute to the Increased Expression of Interleukin-6 in Brain of Aged Mice

Ye, S.-M., & Johnson, R. W. (2001) · Neuroimmunomodulation · doi:10.1159/000049025 · Cited by 203 · see citing works

Fractalkine‐induced activation of the phosphatidylinositol‐3 kinase pathway attentuates microglial activation <i>in vivo</i> and <i>in vitro</i>

Lyons, A., Lynch, A. M., Downer, E. J., Hanley, R., O’Sullivan, J. B., Smith, A., & Lynch, M. A. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.06253.x · Cited by 202 · see citing works

Distribution of the Immune Inhibitory Molecules CD200 and CD200R in the Normal Central Nervous System and Multiple Sclerosis Lesions Suggests Neuron-Glia and Glia-Glia Interactions

Koning, N., Swaab, D. F., Hoek, R. M., & Huitinga, I. (2009) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e3181964113 · Cited by 188 · see citing works

Downregulation of macrophage inhibitory molecules in multiple sclerosis lesions

Koning, N., Bö, L., Hoek, R. M., & Huitinga, I. (2007) · Annals of Neurology · doi:10.1002/ana.21220 · Cited by 186 · see citing works

Neuronal expression of CD22: Novel mechanism for inhibiting microglial proinflammatory cytokine production

Mott, R. T., Ait‐Ghezala, G., Town, T., Mori, T., Vendrame, M., Zeng, J., Ehrhart, J. C., MULLAN, M. J., & Tan, J. (2004) · Glia · doi:10.1002/glia.20009 · Cited by 171 · see citing works

Activation of microglia in the brains of humans with heart disease and hypercholesterolemic rabbits

Streit, W. J., & Sparks, D. L. (1997) · Journal of Molecular Medicine · doi:10.1007/s001090050097 · Cited by 167 · see citing works

Rapid isolation of highly enriched and quiescent microglia from adult rat hippocampus: Immunophenotypic and functional characteristics

Frank, M. G., Wieseler‐Frank, J., Watkins, L. R., & Maier, S. F. (2005) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2005.06.026 · Cited by 164 · see citing works

Immune-based regulation of adult neurogenesis: Implications for learning and memory

Ziv, Y., & Schwartz, M. (2007) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2007.08.006 · Cited by 158 · see citing works

Downregulation of IL-4-induced signalling in hippocampus contributes to deficits in LTP in the aged rat

Maher, F. O., Nolan, Y. M., & Lynch, M. A. (2004) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2004.07.002 · Cited by 153 · see citing works

Microglial degeneration in the aging brain - bad news for neurons?

Streit, W. (2008) · Frontiers in Bioscience · doi:10.2741/2937 · Cited by 150 · see citing works

Expression and regulation of interleukin-1 receptors in the brain. Role in cytokines-induced sickness behavior

Parnet, P. (2002) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(02)00022-x · Cited by 150 · see citing works

Interleukin (IL)-10 inhibits IL-6 production in microglia by preventing activation of NF-κB

Heyen, J. R. R., Ye, S.-M., Finck, B. N., & Johnson, R. W. (2000) · Molecular Brain Research · doi:10.1016/s0169-328x(00)00042-5 · Cited by 146 · see citing works

Interleukin-1 induces c-Fos immunoreactivity in primary afferent neurons of the vagus nerve

Goehler, L. E., Gaykema, R. P. A., Hammack, S. E., Maier, S. F., & Watkins, L. R. (1998) · Brain Research · doi:10.1016/s0006-8993(98)00685-4 · Cited by 146 · see citing works

Neuronal Control of MHC Class II Inducibility in Rat Astrocytes and Microglia

Neumann, H., Boucraut, J., Hahnel, C., Misgeld, T., & Wekerle, H. (1996) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1996.tb01552.x · Cited by 143 · see citing works

Stress-induced increases in hypothalamic IL-1: a systematic analysis of multiple stressor paradigms

Terrence Deak, B., Bordner, K. A., McElderry, N. K., Barnum, C. J., Blandino, P., Deak, M. M., & Tammariello, S. P. (2004) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2004.11.003 · Cited by 143 · see citing works

Elevated Neuronal Expression of CD200 Protects Wlds Mice from Inflammation-Mediated Neurodegeneration

Chitnis, T., Imitola, J., Wang, Y., Elyaman, W., Chawla, P., Sharuk, M., Raddassi, K., Bronson, R. T., & Khoury, S. J. (2007) · American Journal Of Pathology · doi:10.2353/ajpath.2007.060677 · Cited by 142 · see citing works

Consuming a diet supplemented with resveratrol reduced infection-related neuroinflammation and deficits in working memory in aged mice

Abraham, J., & Johnson, R. W. (2009) · Rejuvenation Research · doi:10.1089/rej.2009.0888 · Cited by 131 · see citing works

Neuronal regulation of immune responses in the central nervous system

Tian, L., Rauvala, H., & Gahmberg, C. G. (2009) · Trends in Immunology · doi:10.1016/j.it.2008.11.002 · Cited by 128 · see citing works

Cognitive and neuroinflammatory consequences of mild repeated stress are exacerbated in aged mice

Buchanan, J. B., Sparkman, N. L., Chen, J., & Johnson, R. W. (2008) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2008.02.013 · Cited by 126 · see citing works

Age and Neuroinflammation: A Lifetime of Psychoneuroimmune Consequences

Godbout, J. P., & Johnson, R. W. (2006) · Neurologic Clinics · doi:10.1016/j.ncl.2006.03.010 · Cited by 120 · see citing works

Localization of Interleukin 1 Type I Receptor mRNA in Rat Brain

Wong, M., & Licinio, J. (2006) · NeuroImmunoModulation · doi:10.1159/000097143 · Cited by 118 · see citing works

Aging sensitizes rapidly isolated hippocampal microglia to LPS ex vivo

Frank, M. G., Barrientos, R. M., Watkins, L. R., & Maier, S. F. (2010) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2010.05.022 · Cited by 109 · see citing works

Early-life infection is a vulnerability factor for aging-related glial alterations and cognitive decline

Bilbo, S. D. (2010) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2010.04.001 · Cited by 108 · see citing works

CNS inflammation and neuronal degeneration is aggravated by impaired CD200–CD200R-mediated macrophage silencing

Meuth, S. G., Simon, O. J., Grimm, A. M., Melzer, N., Herrmann, A. M., Spitzer, P., Landgraf, P., & Wiendl, H. (2008) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2007.11.013 · Cited by 107 · see citing works

The role of IL-1β in stress-induced sensitization of proinflammatory cytokine and corticosterone responses

Johnson, J. D., O’Connor, K., Watkins, L. R., & Maier, S. F. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.05.046 · Cited by 107 · see citing works

Vagotomy attenuates the behavioural but not the pyrogenic effects of interleukin-1 in rats

Luheshi, G. N., Bluthé, R.-M., Rushforth, D. A., MULCAHY, N., Konsman, J. P., Goldbach, M., & Dantzer, R. (2000) · Autonomic Neuroscience · doi:10.1016/s1566-0702(00)00231-9 · Cited by 106 · see citing works

Influence of poly I:C on sickness behaviors, plasma cytokines, corticosterone and central monoamine activity: Moderation by social stressors

Gandhi, R., Hayley, S. P., Gibb, J., Merali, Z., & Anisman, H. (2007) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2006.12.005 · Cited by 104 · see citing works

In vivo neutralization of endogenous brain fractalkine increases hippocampal TNFα and 8-isoprostane production induced by intracerebroventricular injection of LPS

Zujovic, V., Schussler, N., Jourdain, D., Duverger, D., & Taupin, V. (2001) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(01)00259-4 · Cited by 102 · see citing works

Decreased neuronal CD200 expression in IL-4-deficient mice results in increased neuroinflammation in response to lipopolysaccharide

Lyons, A., McQuillan, K., Deighan, B. F., O’Reilly, J.-A., Downer, E. J., Murphy, A. C., Watson, M., Piazza, A., O’Connell, F., Griffin, R., et al. (2009) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2009.05.060 · Cited by 98 · see citing works

Pharmacologic suppression of neuronal oxidative damage and dendritic degeneration following direct activation of glial innate immunity in mouse cerebrum

Milatović, D., Zaja‐Milatovic, S., Montine, K. S., Horner, P. J., & Montine, T. J. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.02120.x · Cited by 96 · see citing works

Exposure to forced swim stress does not alter central production of IL-1

Terrence Deak, B., Bellamy, C., & D’Agostino, L. G. (2003) · Brain Research · doi:10.1016/s0006-8993(03)02485-5 · Cited by 94 · see citing works

Stereological estimation of total microglia number in mouse hippocampus

Long, J. M., Kalehua, A. N., Muth, N. J., Hengemihle, J. M., Jucker, M., Calhoun, M. E., Ingram, D. K., & Mouton, P. R. (1998) · Journal of Neuroscience Methods · doi:10.1016/s0165-0270(98)00100-9 · Cited by 87 · see citing works

Interleukin-4 mediates the neuroprotective effects of rosiglitazone in the aged brain

Loane, D. J., Deighan, B. F., Clarke, R. M., Griffin, R. J., Lynch, A. M., & Lynch, M. A. (2007) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2007.09.001 · Cited by 87 · see citing works

Architectural changes to CA1 pyramidal neurons in adult and aged mice after peripheral immune stimulation

Richwine, A. F., Parkin, A. O., Buchanan, J. B., Chen, J., Markham, J. A., Juraska, J. M., & Johnson, R. W. (2008) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2008.08.003 · Cited by 87 · see citing works

CD200R1 Agonist Attenuates Mechanisms of Chronic Disease in a Murine Model of Multiple Sclerosis

Liu, Y., Bandô, Y., Vargas-Lowy, D., Elyaman, W., Khoury, S. J., Huang, T., Reif, K., & Chitnis, T. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.4272-09.2010 · Cited by 85 · see citing works

Neither acute nor chronic exposure to a naturalistic (predator) stressor influences the interleukin-1β system, tumor necrosis factor-α, transforming growth factor-β1, and neuropeptide mRNAs in specific brain regions

Plata‐Saláman, C. R., Ilyin, S. E., Turrin, N. P., Gayle, D. A., Flynn, M. C., Bedard, T., Merali, Z., & Anisman, H. (2000) · Brain Research Bulletin · doi:10.1016/s0361-9230(99)00204-x · Cited by 84 · see citing works

Functional expression of the fractalkine (CX3C) receptor and its regulation by lipopolysaccharide in rat microglia

Boddeke, E., Meigel, I., Frentzel, S., Biber, K. P. H., Renn, L. Q., & Gebicke‐Haerter, P. J. (1999) · European Journal of Pharmacology · doi:10.1016/s0014-2999(99)00307-6 · Cited by 83 · see citing works

Microglial activation induces cell death, inhibits neurite outgrowth and causes neurite retraction of differentiated neuroblastoma cells

Münch, G. W., Gasic‐Milenkovic, J., Dukić-Stefanović, S., Kuhla, B., Heinrich, K., Riederer, P. F., Huttunen, H. J., Founds, H., & Sajithlal, G. B. (2003) · Experimental Brain Research · doi:10.1007/s00221-003-1389-5 · Cited by 82 · see citing works

Regulation of microglial cell responses in murine Toxoplasma encephalitis by CD200/CD200 receptor interaction

Deckert, M., Sedgwick, J. D., Fischer, E., & Schlüter, D. (2006) · Acta Neuropathologica · doi:10.1007/s00401-006-0062-z · Cited by 82 · see citing works

A novel anti-inflammatory role of NCAM-derived mimetic peptide, FGL

Downer, E. J., Cowley, T. R., Lyons, A., Mills, K. H. G., Berezin, V., Bock, E., & Lynch, M. A. (2008) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2008.03.017 · Cited by 81 · see citing works

Glucocorticoids: Protectors of the Brain during Innate Immune Responses

Glezer, I., & Rivest, S. (2004) · The Neuroscientist · doi:10.1177/1073858404263494 · Cited by 79 · see citing works

Immunity to self and self-maintenance: a unified theory of brain pathologies

Schwartz, M., & Ziv, Y. (2008) · Trends in Immunology · doi:10.1016/j.it.2008.01.003 · Cited by 74 · see citing works

Aging sensitizes mice to behavioral deficits induced by central HIV-1 gp120

Abraham, J., Jang, S., Godbout, J. P., Chen, J., Kelley, K. W., Dantzer, R., & Johnson, R. W. (2006) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2006.11.002 · Cited by 72 · see citing works

Interleukin-1β exerts a myriad of effects in the brain and in particular in the hippocampus: Analysis of some of these actions

Lynch, M. A. (2002) · Vitamins and hormones · doi:10.1016/s0083-6729(02)64006-3 · Cited by 71 · see citing works

A synthetic NCAM‐derived mimetic peptide, FGL, exerts anti‐inflammatory properties via IGF‐1 and interferon‐γ modulation

Downer, E. J., Cowley, T. R., Cox, F., Maher, F. O., Berezin, V., Bock, E., & Lynch, M. A. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.06076.x · Cited by 36 · see citing works

Interleukin-1β interferes with signal transduction induced by neurotrophin-3 in cortical neurons

Soi‐ampornkul, R., Tong, L., Thangnipon, W., Balázs, R., & Cotman, C. W. (2007) · Brain Research · doi:10.1016/j.brainres.2007.10.051 · Cited by 25 · see citing works

Localization of interleukin 1 type I receptor mRNA in rat brain

Licinio, J., & Wong, M. (1994) · Biological Psychiatry · doi:10.1016/0006-3223(94)91078-2 · Cited by 17 · see citing works

Untitled work

Zujovic (2000) · doi:10.1002/(sici)1098-1136(20000215)29:4

Neuroinflammation: The Devil Is in the Details

DiSabato, D. J., Quan, N., & Godbout, J. P. (2016) · Journal of Neurochemistry · doi:10.1111/jnc.13607 · Cited by 1,640 · see citing works

Review: microglia of the aged brain: primed to be activated and resistant to regulation

Norden, D. M., & Godbout, J. P. (2013) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.2012.01306.x · Cited by 792 · see citing works

Integrating neuroimmune systems in the neurobiology of depression

Wohleb, E. S., Franklin, T., Iwata, M., & Duman, R. S. (2016) · Nature Reviews Neuroscience · doi:10.1038/nrn.2016.69 · Cited by 668 · see citing works

Microglial priming and enhanced reactivity to secondary insult in aging, and traumatic CNS injury, and neurodegenerative disease

Norden, D. M., Muccigrosso, M. M., & Godbout, J. P. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.10.028 · Cited by 413 · see citing works

Microglia Priming with Aging and Stress

Niraula, A., Sheridan, J. F., & Godbout, J. P. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2016.185 · Cited by 398 · see citing works

Neuroplastic changes in depression: A role for the immune system

Eyre, H., & Baune, B. T. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.03.019 · Cited by 319 · see citing works

Influenza Infection Induces Neuroinflammation, Alters Hippocampal Neuron Morphology, and Impairs Cognition in Adult Mice

Jurgens, H. A., Amancherla, K., & Johnson, R. W. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.6389-11.2012 · Cited by 243 · see citing works

Lipopolysaccharide-induced interleukin (IL)-4 receptor-α expression and corresponding sensitivity to the M2 promoting effects of IL-4 are impaired in microglia of aged mice

Fenn, A. M., Henry, C. J., Huang, Y., Dugan, A., & Godbout, J. P. (2012) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2011.10.003 · Cited by 198 · see citing works

Microglia: A Central Player in Depression

Deng, S.-L., Chen, J.-G., & Wang, F. (2020) · Current Medical Science · doi:10.1007/s11596-020-2193-1 · Cited by 119 · see citing works

T cell infiltration and upregulation of MHCII in microglia leads to accelerated neuronal loss in an α-synuclein rat model of Parkinson’s disease

Subbarayan, M. S., Hudson, C., Moss, L. D., Nash, K. R., & Bickford, P. C. (2020) · Journal of Neuroinflammation · doi:10.1186/s12974-020-01911-4 · Cited by 107 · see citing works

Potent and multiple regulatory actions of microglial glucocorticoid receptors during CNS inflammation

Carrillo-de Sauvage, M. Á., Maatouk, L., Arnoux, I., Pasco, M., Sanz Diez, A., Delahaye, M., Herrero, M. T., Newman, T. A., Calvo, C. F., Audinat, E., et al. (2013) · Cell Death &amp; Differentiation · doi:10.1038/cdd.2013.108 · Cited by 114 · see citing works

Insensitivity of astrocytes to interleukin 10 signaling following peripheral immune challenge results in prolonged microglial activation in the aged brain

Norden, D. M., Trojanowski, P. J., Walker, F. R., & Godbout, J. P. (2016) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2016.04.014 · Cited by 73 · see citing works

The effect of aged microglia on synaptic impairment and its relevance in neurodegenerative diseases

Triviño, J. J., & von Bernhardi, R. (2021) · Neurochemistry International · doi:10.1016/j.neuint.2021.104982 · Cited by 43 · see citing works

Ageing and recurrent episodes of neuroinflammation promote progressive experimental autoimmune encephalomyelitis in Biozzi <scp>ABH</scp> mice

Peferoen, L. A. N., Breur, M., van de Berg, S., Peferoen‐Baert, R., Boddeke, E. H. W. G. M., van der Valk, P., Pryce, G., van Noort, J. M., Baker, D., & Amor, S. (2016) · Immunology · doi:10.1111/imm.12644 · Cited by 41 · see citing works

Neurogenesis and Neuroinflammation in Dialogue: Mapping Gaps, Modulating Microglia, Rewiring Aging

Tanaka, M. (2026) · Cells · doi:10.3390/cells15010078 · Cited by 11 · see citing works

"Lipopolysaccharide-induced animal models for neuroinflammation – An overview."

Silva, A., Fiadeiro, M. B., Bernardino, L. I., Fonseca, C. P., Baltazar, G., & Cristóvão, A. C. (2023) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2023.578273 · Cited by 76 · see citing works

Characterisation of ReNcells CX and VM stimulated with interleukin-1β and lipopolysaccharide

Cheung, K. A. K., Abeysinghe, P., Vaswani, K., et al. (2022) · Neurochemistry International · doi:10.1016/j.neuint.2022.105326 · Cited by 4 · see citing works

Role of Neuroinflammation in the Trajectory of Alzheimer’s Disease and in vivo Quantification Using PET

Edison, P., & Brooks, D. J. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-179929 · Cited by 62 · see citing works

Alzheimer’s Disease Research Using Human Microglia

Lue, L., Beach, T. G., & Walker, D. G. (2019) · Cells · doi:10.3390/cells8080838 · Cited by 26 · see citing works

A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation

Voet, S., Mc Guire, C., Hagemeyer, N., Martens, A., Schroeder, A., Wieghofer, P., Daems, C., Staszewski, O., Vande Walle, L., Jordao, M. J. C., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-04376-5 · Cited by 227 · see citing works