Balasubramanian, Shankar

Accurate whole human genome sequencing using reversible terminator chemistry

Bentley, D. R., Balasubramanian, S., Swerdlow, H. P., Smith, G. P., Milton, J., Brown, C. G., Hall, K. P., Evers, D. J., Barnes, C. L., Bignell, H. R., et al. (2008) · Nature

Genomics and Phylogenetic StudiesGenomics and Rare Diseases

Cited by 3,684

Early Detection of Cancer

Crosby, D., Bhatia, S., Brindle, K. M., Coussens, L. M., Dive, C., Emberton, M., Esener, S., Fitzgerald, R. C., Gambhir, S. S., Kuhn, P., et al. (2022) · Science

Global Cancer Incidence and ScreeningCancer Genomics and Diagnostics

Cited by 1,379

G-quadruplex structures mark human regulatory chromatin

Hänsel-Hertsch, R., Beraldi, D., Lensing, S. V., Marsico, G., Zyner, K., Parry, A., Di Antonio, M., Pike, J., Kimura, H., Narita, M., et al. (2016) · Nature Genetics

DNA and Nucleic Acid ChemistryGenomics and Chromatin Dynamics

Cited by 964

The Structure and Function of DNA G-Quadruplexes

Spiegel, J., Adhikari, S., & Balasubramanian, S. (2020) · Trends in Chemistry

DNA and Nucleic Acid ChemistryAdvanced biosensing and bioanalysis techniques

Cited by 920

An RNA G-quadruplex in the 5′ UTR of the NRAS proto-oncogene modulates translation

Kumari, S., Bugaut, A., Huppert, J. L., & Balasubramanian, S. (2007) · Nature Chemical Biology

DNA and Nucleic Acid ChemistryRNA and protein synthesis mechanisms

Cited by 822

Small-molecule–induced DNA damage identifies alternative DNA structures in human genes

Rodriguez, R., Miller, K. M., Forment, J. V., Bradshaw, C. R., Nikan, M., Britton, S., Oelschlaegel, T., Xhemalce, B., Balasubramanian, S., & Jackson, S. P. (2012) · Nature Chemical Biology

DNA and Nucleic Acid ChemistryMetal complexes synthesis and properties

Cited by 741

A Novel Small Molecule That Alters Shelterin Integrity and Triggers a DNA-Damage Response at Telomeres

Rodriguez, R., Müller, S., Yeoman, J. A., Trentesaux, C., Riou, J.-F., & Balasubramanian, S. (2008) · Journal of the American Chemical Society

Telomeres, Telomerase, and SenescenceDNA and Nucleic Acid Chemistry

Cited by 517

METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation

Pandolfini, L., Barbieri, I., Bannister, A. J., Hendrick, A., Andrews, B., Webster, N., Murat, P., Mach, P., Brandi, R., Robson, S. C., et al. (2019) · Molecular Cell

RNA modifications and cancerRNA regulation and disease

Cited by 491

FANCJ Is a Structure-specific DNA Helicase Associated with the Maintenance of Genomic G/C Tracts

London, T. B. C., Barber, L. J., Mosedale, G., Kelly, G. P., Balasubramanian, S., Hickson, I. D., Boulton, S. J., & Hiom, K. (2008) · Journal of Biological Chemistry

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 252

Landscape of G-quadruplex DNA structural regions in breast cancer

Hänsel-Hertsch, R., Simeone, A., Shea, A., Hui, W. W. I., Zyner, K. G., Marsico, G., Rueda, O. M., Bruna, A., Martin, A., Zhang, X., et al. (2020) · Nature Genetics

DNA and Nucleic Acid ChemistryGenomics and Chromatin Dynamics

Cited by 223

Elevated Levels of G-Quadruplex Formation in Human Stomach and Liver Cancer Tissues

Biffi, G., Tannahill, D., Miller, J., Howat, W. J., & Balasubramanian, S. (2014) · PLoS ONE

DNA and Nucleic Acid ChemistryAdvanced biosensing and bioanalysis techniques

Cited by 223

Rudimentary G-quadruplex-based telomere capping in Saccharomyces cerevisiae

Smith, J. S., Chen, Q., Yatsunyk, L. A., Nicoludis, J. M., Garcia, M. S., Kranaster, R., Balasubramanian, S., Monchaud, D., Teulade-Fichou, M.-P., Abramowitz, L., et al. (2011) · Nature Structural & Molecular Biology

Telomeres, Telomerase, and SenescenceDNA and Nucleic Acid Chemistry

Cited by 135

NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence

Parry, A. J., Hoare, M., Bihary, D., Hänsel-Hertsch, R., Smith, S., Tomimatsu, K., Mannion, E., Smith, A., D’Santos, P., Russell, I. A., et al. (2018) · Nature Communications

Telomeres, Telomerase, and SenescenceGenomics and Chromatin Dynamics

Cited by 102

Single-cell mapping of DNA G-quadruplex structures in human cancer cells

Hui, W. W. I., Simeone, A., Zyner, K. G., Tannahill, D., & Balasubramanian, S. (2021) · Scientific Reports

DNA and Nucleic Acid ChemistryGenomics and Chromatin Dynamics

Cited by 85

Sequencing abasic sites in DNA at single-nucleotide resolution

Liu, Z. J., Martínez Cuesta, S., van Delft, P., & Balasubramanian, S. (2019) · Nature Chemistry

DNA and Nucleic Acid ChemistryDNA Repair Mechanisms

Cited by 83

An Epigenetics‐Inspired DNA‐Based Data Storage System

Mayer, C., McInroy, G. R., Murat, P., Van Delft, P., & Balasubramanian, S. (2016) · Angewandte Chemie

DNA and Biological ComputingAdvanced biosensing and bioanalysis techniques

Cited by 19

Identification of putative reader proteins of 5-methylcytosine and its derivatives in Caenorhabditis elegans RNA

Navarro, I. C., Suen, K. M., Bensaddek, D., Tanpure, A., Lamond, A., Balasubramanian, S., & Miska, E. A. (2022) · Wellcome Open Research

RNA modifications and cancerRNA regulation and disease

Cited by 3