Benoist, Christophe

Intersection of population variation and autoimmunity genetics in human T cell activation

Ye, C. J., Feng, T., Kwon, H.-K., Raj, T., Wilson, M. T., Asinovski, N., McCabe, C., Lee, M. H., Frohlich, I., Paik, H.-I., et al. (2014) · Science

T-cell and B-cell ImmunologyGenetic Associations and Epidemiology

Cited by 236

TCR Transgenic Mice Reveal Stepwise, Multi-site Acquisition of the Distinctive Fat-Treg Phenotype

Li, C., DiSpirito, J. R., Zemmour, D., Spallanzani, R. G., Kuswanto, W., Benoist, C., & Mathis, D. (2018) · Cell

T-cell and B-cell ImmunologyAdipokines, Inflammation, and Metabolic Diseases

Cited by 231

Noninvasive imaging of pancreatic islet inflammation in type 1A diabetes patients

Gaglia, J. L., Guimaraes, A. R., Harisinghani, M., Turvey, S. E., Jackson, R., Benoist, C., Mathis, D., & Weissleder, R. (2011) · Journal of Clinical Investigation

Diabetes and associated disordersPancreatic function and diabetes

Cited by 209

Back to central tolerance

Mathis, D., & Benoist, C. (2004) · Immunity

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 198

Appearance and disappearance of the mRNA signature characteristic of T reg cells in visceral adipose tissue: Age, diet, and PPARγ effects

Cipolletta, D., Cohen, P., Spiegelman, B. M., Benoist, C., & Mathis, D. (2015) · Proceedings of the National Academy of Sciences

Adipokines, Inflammation, and Metabolic DiseasesT-cell and B-cell Immunology

Cited by 186

Genetic determinants of co-accessible chromatin regions in activated T cells across humans

Gate, R. E., Cheng, C. S., Aiden, A. P., Siba, A., Tabaka, M., Lituiev, D., Machol, I., Gordon, M. G., Subramaniam, M., Shamim, M., et al. (2018) · Nature Genetics

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 181

Interleukin-6 produced by enteric neurons regulates the number and phenotype of microbe-responsive regulatory T cells in the gut

Yan, Y., Ramanan, D., Rozenberg, M., McGovern, K., Rastelli, D., Vijaykumar, B., Yaghi, O., Voisin, T., Mosaheb, M., Chiu, I., et al. (2021) · Immunity

T-cell and B-cell ImmunologyGastrointestinal motility and disorders

Cited by 165

Nuclear receptor Nr4a1 modulates both regulatory T-cell (Treg) differentiation and clonal deletion

Fassett, M. S., Jiang, W., D'Alise, A. M., Mathis, D., & Benoist, C. (2012) · Proceedings of the National Academy of Sciences

T-cell and B-cell ImmunologyNuclear Receptors and Signaling

Cited by 126

Regulatory T cells in the face of the intestinal microbiota

Ramanan, D., Pratama, A., Zhu, Y., Venezia, O., Sassone-Corsi, M., Chowdhary, K., Galván-Peña, S., Sefik, E., Brown, C., Gélineau, A., et al. (2023) · Nature Reviews Immunology

T-cell and B-cell ImmunologyGut microbiota and health

Cited by 126

The gut microbiota promotes distal tissue regeneration via RORγ+ regulatory T cell emissaries

Hanna, B. S., Wang, G., Galván-Peña, S., Mann, A. O., Ramirez, R. N., Muñoz-Rojas, A. R., Smith, K., Wan, M., Benoist, C., & Mathis, D. (2023) · Immunity

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 126

Accurate measurement of pancreatic islet β-cell mass using a second-generation fluorescent exendin-4 analog

Reiner, T., Thurber, G., Gaglia, J., Vinegoni, C., Liew, C. W., Upadhyay, R., Kohler, R. H., Li, L., Kulkarni, R. N., Benoist, C., et al. (2011) · Proceedings of the National Academy of Sciences

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 120

A dynamic atlas of immunocyte migration from the gut

Galván-Peña, S., Zhu, Y., Hanna, B. S., Mathis, D., & Benoist, C. (2024) · Science Immunology

T-cell and B-cell ImmunologyGut microbiota and health

Cited by 74

Age-related tumor growth in mice is related to integrin α 4 in CD8+ T cells

Oh, J., Magnuson, A., Benoist, C., Pittet, M. J., & Weissleder, R. (2018) · JCI Insight

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 51

FOXP3 recognizes microsatellites and bridges DNA through multimerization

Zhang, W., Leng, F., Wang, X., Ramirez, R. N., Park, J., Benoist, C., & Hur, S. (2023) · Nature

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 42

Fluorescent exendin-4 derivatives for pancreatic β-cell analysis

Clardy, S. M., Keliher, E. J., Mohan, J. F., Sebas, M., Benoist, C., Mathis, D., & Weissleder, R. (2014) · Bioconjugate Chemistry

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 41

Publisher Correction: Single-cell gene expression reveals a landscape of regulatory T cell phenotypes shaped by the TCR

Zemmour, D., Zilionis, R., Kiner, E., Klein, A. M., Mathis, D., & Benoist, C. (2018) · Nature Immunology

T-cell and B-cell ImmunologySingle-cell and spatial transcriptomics

Cited by 5

Regulatory T cells safeguard liver health during metabolic-associated steatohepatitis

Hanna, B. S., Langston, P. K., Marin-Rodero, M., Ramirez, R. N., Wan, M., Benoist, C., & Mathis, D. (2026) · Proceedings of the National Academy of Sciences

Liver Disease Diagnosis and TreatmentLiver Diseases and Immunity

Cited by 1