Schwarzschild, Michael A.

Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine

Huang, Z.-L., Qu, W.-M., Eguchi, N., Chen, J.-F., Schwarzschild, M. A., Fredholm, B. B., Urade, Y., & Hayaishi, O. (2005) · Nature Neuroscience

Adenosine and Purinergic SignalingCoffee research and impacts

Cited by 640

Physical activity and the risk of Parkinson disease

Chen, H., Zhang, S. M., Schwarzschild, M. A., Hernán, M. A., & Ascherio, A. (2005) · Neurology

Parkinson's Disease Mechanisms and TreatmentsPhysical Activity and Health

Cited by 371

Incidence of Parkinson disease in North America

Willis, A. W., Roberts, E., Beck, J. C., Fiske, B., Ross, W., Savica, R., Van Den Eeden, S. K., Tanner, C. M., Marras, C., on behalf of the Parkinson’s Foundation P4 Group, et al. (2022) · npj Parkinson's Disease

Parkinson's Disease Mechanisms and TreatmentsDementia and Cognitive Impairment Research

Cited by 341

Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases

Espay, A. J., Vizcarra, J. A., Marsili, L., Lang, A. E., Simon, D. K., Merola, A., Josephs, K. A., Fasano, A., Morgante, F., Savica, R., et al. (2019) · Neurology

Parkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

Cited by 274

Caffeine and risk of Parkinson’s disease in a large cohort of men and women

Palacios, N., Gao, X., McCullough, M. L., Schwarzschild, M. A., Shah, R., Gapstur, S., & Ascherio, A. (2012) · Movement Disorders

Parkinson's Disease Mechanisms and TreatmentsCoffee research and impacts

Cited by 185

Recreational physical activity and risk of Parkinson's disease

Thacker, E. L., Chen, H., Patel, A. V., McCullough, M. L., Calle, E. E., Thun, M. J., Schwarzschild, M. A., & Ascherio, A. (2008) · Movement Disorders

Parkinson's Disease Mechanisms and TreatmentsPhysical Activity and Health

Cited by 185

Efficacy of Nilotinib in Patients With Moderately Advanced Parkinson Disease: A Randomized Clinical Trial

Simuni, T., Fiske, B., Merchant, K., Coffey, C. S., Klingner, E., Caspell-Garcia, C., Lafontant, D.-E., Matthews, H., Wyse, R. K., Brundin, P., et al. (2021) · JAMA Neurology

Parkinson's Disease Mechanisms and TreatmentsDeep Brain Stimulation and Movement Disorders

Cited by 149

KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients

Quinti, L., Dayalan Naidu, S., Träger, U., Chen, X., Kegel-Gleason, K., Llères, D., Connolly, C., Chopra, V., Low, C., Moniot, S., et al. (2017) · Proceedings of the National Academy of Sciences

Genomics, phytochemicals, and oxidative stressGenetic Neurodegenerative Diseases

Cited by 140

Genome-wide survival study identifies a novel synaptic locus and polygenic score for cognitive progression in Parkinson’s disease

Liu, G., Peng, J., Liao, Z., Locascio, J. J., Corvol, J.-C., Zhu, F., Dong, X., Maple-Grødem, J., Campbell, M. C., Elbaz, A., et al. (2021) · Nature Genetics

Parkinson's Disease Mechanisms and TreatmentsGenetic Associations and Epidemiology

Cited by 127

Genetic determinants of hair color and parkinson's disease risk

Gao, X., Simon, K. C., Han, J., Schwarzschild, M. A., & Ascherio, A. (2009) · Annals of Neurology

Parkinson's Disease Mechanisms and Treatmentsmelanin and skin pigmentation

Cited by 116

A prospective study of bowel movement frequency and risk of Parkinson's disease

Gao, X., Chen, H., Schwarzschild, M. A., & Ascherio, A. (2011) · American Journal of Epidemiology

Parkinson's Disease Mechanisms and TreatmentsGastrointestinal motility and disorders

Cited by 115

Intake of antioxidant vitamins and risk of Parkinson's disease

Hughes, K. C., Gao, X., Kim, I. Y., Rimm, E. B., Wang, M., Weisskopf, M. G., Schwarzschild, M. A., & Ascherio, A. (2016) · Movement Disorders

Parkinson's Disease Mechanisms and TreatmentsAntioxidant Activity and Oxidative Stress

Cited by 110

Parkinson’s disease variant detection and disclosure: PD GENEration, a North American study

Cook, L., Verbrugge, J., Schwantes-An, T.-H., Schulze, J., Foroud, T., Hall, A., Marder, K. S., Mata, I. F., Mencacci, N. E., Nance, M. A., et al. (2024) · Brain

Parkinson's Disease Mechanisms and TreatmentsGenomics and Rare Diseases

Cited by 108

A prospective study of night shift work, sleep duration, and risk of Parkinson's disease

Chen, H., Schernhammer, E., Schwarzschild, M. A., & Ascherio, A. (2006) · American Journal of Epidemiology

Parkinson's Disease Mechanisms and TreatmentsSleep and Work-Related Fatigue

Cited by 85

Metagenomics of the Gut Microbiome in Parkinson's Disease: Prodromal Changes

Palacios, N., Wilkinson, J., Bjornevik, K., Schwarzschild, M. A., McIver, L., Ascherio, A., & Huttenhower, C. (2023) · Annals of Neurology

Parkinson's Disease Mechanisms and TreatmentsGut microbiota and health

Cited by 59

Do caffeine and more selective adenosine A2A receptor antagonists protect against dopaminergic neurodegeneration in Parkinson's disease?

Chen, J.-F., & Schwarzschild, M. A. (2020) · Parkinsonism & Related Disorders

Parkinson's Disease Mechanisms and TreatmentsAdenosine and Purinergic Signaling

Cited by 39